7,188 research outputs found
Automated model structure variation and policy robustness testing: A procedure for innovation diffusion models
No full textn this paper we present a procedure that enables a systematic and partially automated parameterization and selection of agent-based models of the diffusion of innovations and policies to support diffusion processes. A prototype on the diffusion of water saving shower heads is presented. Our results suggest that the presented approach can adequately and systematically evaluate different sets of parameters and model structures against known diffusion data.Energie and Industri
Author Checklist - Full - Ahmed Essa_ 135540.pdf
No full textAttached is a required author checklist for animal research </p
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Modification data for the end of term American Foreign Policy essay
No full textDataset and do file used for the end of term essa
Connections between Author and Narrator-protagonist: Autofiction in Essa gente, by Chico Buarque de Holanda
No full textO presente artigo propõe uma análise do romance Essa gente (2019), de Chico Buarque de Holanda, visando examinar aspectos da obra que evidenciam intersecções entre a vida do escritor e a história narrada. Parte-se do pressuposto de que o romance, escrito em primeira pessoa pelo protagonista, se situa no limiar entre autobiografia e ficção, no tipo de narrativa conhecido como autoficção, muito difundido atualmente. O hibridismo desse tipo de escrita de si convida o leitor a um constante questionamento sobre o que pertence à vida do autor e o que é construção ficcional. O aporte teórico para a discussão sobre a natureza da narrativa autoficcional será retirado dos estudos de Leyla Perrone-Moisés (2016), Karl Erik Schollhammer (2009), Serge Doubrovsky (2014), Luciene Azevedo (2008), Diana Klinger (2006) e Anna Faedrich (2015). O autor constrói um texto ambíguo e irônico no qual elementos autobiográficos e fictícios se entrelaçam possibilitando uma reflexão profunda sobre conflitos afetivos, declínios sociais, cicatrizes históricas e sobre a turbulenta conjuntura política brasileira de 2016 a 2019.
PALAVRAS-CHAVE: Essa gente; Chico Buarque; autoficção.This article offers an analysis of the novel Essa Gente (2019) by Chico Buarque de Holanda and seeks to examine aspects of the narrative that show possible intersections between the author’s life and the story told. The assumption is that the novel, told in the first person by the main character, stands on the threshold between autobiography and fiction, falling into the category known as autofiction, a form of narrative quite popular nowadays. The hybridity of this type of self-writing invites the reader to a constant questioning about what belongs to the author’s life and what is fictional creation. The theoretical support for the discussion on the nature of the autofictional text will be taken from the work of Leyla Perrone-Moisés (2016), Karl Erik Schollhammer (2009), Serge Doubrovsky (2014), Luciene Azevedo (2008), Diana Klinger (2006), and Anna Faedrich (2015). The author creates an ambiguous and ironic story in which autobiographical and fictional elements intertwine, promoting a deep reflection on affective conflicts, social declines, historical scars, and on the turbulent Brazilian political situation from 2016 to 2019.
KEYWORDS: Essa gente; Chico Buarque; autofiction
Placebo and Nocebo Responses in Gabapentin Enacarbil and Pregabalin Trials for Restless Legs Syndrome:Time-Course Model-Based Network Meta-Analysis and Meta-analysis of Proportions
No full textPurpose:Placebo responses are often stronger in randomized controlled trials (RCT) on conditions that measure subjective improvement in symptoms, such as restless legs syndrome (RLS). This meta-analysis sought to quantify both placebo and nocebo responses in published RCTs of gabapentin enacarbil (GEn) and pregabalin.Methods:In the first meta-analytic approach, we evaluated the time-courses taken by the participants randomized to the different doses of GEn and pregabalin and to placebo in their responses in International RLS Study Group Rating Scale (IRLS) scores. This was primarily evaluated by estimating the posterior median ET50s, the time (days) at which 50% of maximum response was achieved in IRLS scores for these participants. In a second meta-analytic approach, one-arm meta-analyses estimated proportions of participants on placebo considered “responders” on the investigator-initiated Clinical Global Impression-Improvement (CGI-I) scale, and separately of those who developed somnolence and dizziness. Results:A total of 16 RCTs were included in this meta-analysis. Relative differences in ET50s (median and 95% credible intervals) between GEn 600, 900, 1200, 1800, 2400 mg/d doses and placebo were 1.09 (0.07; 2.92), 1.35 (0.05; 5.85), 0.56 (0.02; 1.79), 0.62 (0.03; 2.34) and 1.61 (0.10; 5.22) days, respectively, and between pregabalin mean doses of 107.8 and 337.5 mg/d and placebo were 21.75 (0.89; 145.26) and 2.54 (0.12; 8.41) days, respectively, indicating largely clinically insignificant differences. Pooled proportion of CGI-I responders amongst the participants randomized to placebo was 0.40 [(95% confidence intervals (CI): 0.31; 0.49), I2=84%]. Duration of RCTs and previous RLS treatment were associated with CGI-I response based on meta-regression analyses. Pooled proportions of participants randomized to placebo who developed somnolence and dizziness were 0.05 [(95%CIs: 0.03; 0.08), I2=75%], and 0.02 [(95%CIs: 0.01; 0.04), I2=62%], respectively. Conclusions:GEn and pregabalin showed substantial placebo responses in RCTs. Further studies are needed that would identify predictor variables for placebo responders or non-responders
A Rare Intrascrotal Metastases From Renal Cell Carcinoma: A Case Report
No full textAbstractMetastatic renal cell carcinoma is potentially a lethal disease with in some cases aggressive behavior. The given fact that the patterns of metastases from RCC are not clearly identified, which may involve some rare metastatic locations. We present a case of 58 years old male presented with painless left scrotal mass, which was discovered to be an intrascrotal metastases appeared 3 years after nephrectomy for ipsilateral renal cell carcinoma. We believe that the rarity of the metastatic site and the intriguing possible mechanism of spread make an interesting case for clinicians and could add more follow-up measures for patients treated from renal cell carcinoma
Second language word processing in sentence contexts: Pre-lexical prediction versus post-lexical integration
No full textThis study investigated the effects of sentence contexts on the second language (L2) word recognition process. It aims at finding whether second language (L2) learners of English perform similar to English native speakers in terms of using the sentence context to predict upcoming word in their L2. A group of L2 participants and a control group of native speakers (L1) participants performed a cross-modal priming task in which they were asked to make a lexical decision on a visually presented word while listening to a semantically related or non- related English sentence. The test was conducted to determine whether both groups of participants were able to predict an upcoming word based on the context of the preceding sentence that is auditorily presented. The study is conducted using PsychoPy software whereas the data was analyzed using linear-mixed effects modeling in RStudio software. The results showed that the L1 speakers were able to predict an upcoming word based on the context of the preceding sentence. That is, a significantly faster recognition of the related word was observed compared to the less related words. On other hand, the English second language participants were not as able to predict an upcoming word as quickly as the English native speaker participants were. However, the L2 participants showed post-access lexical processing or what is called an integrating process of the presented word to the previous sentence context. That is, an effect of the sentence context was observed with L2 participants, yet only after reading the presented word, they decide whether it is appropriate to the preceding sentence context or not.
Acknowledgments
The author is thankful to the Deanship of Scientific Research at Najran University for funding this work under the National Research Priorities funding program.
Author: Essa Qurbi,
0000-0002-7073-0602 [email protected]
The 'true use of reading' : Sarah Fielding and mid eighteenth-century literary strategies.
No full textPhDThe aim of this thesis is to explore, by examining her life and
works, how Sarah Fielding (1710-68) established her identity as an author.
The definition of her role involves her notions of the functions of
writing and reading.
Sarah Fielding attempts to invite readers to form a sense of ties
by tacit understanding of her messages. As she believes that a work
of literature is produced through collaboration between the writer and
the reader, it is an important task in her view to show her attentiveness
toward reading practice. In her consideration of reading, she has two
distinct, even opposite views of her audience: on the one hand a familiar
and limited circle of readers with shared moral and cultural values and
on the other potential readers among the unknown mass of people. The
dual targets direct her to devise various strategies. She tries to
appeal to those who can endorse and appreciate her moral values as well
as her learning. Her writings and letters testify that she is sensitive
to the demands of the literary market, trying to lead the taste of readers
by inventing new forms.
The thesis opens with an overview of Sarah Fielding's career,
followed by a consideration of her critical attention to the roles of
reading. I go on to examine the narrative structures and strategies
she deploys, with a particular emphasis on her use of the epistolary
method. The following chapter deals with her attention to the reading
of the moral message tangibly embodied in her educational writing. It
is followed by an analysis of the activity which earned her a reputation
as a learned woman. Various as the forms of her works are, they invariably
reflect her attempt to balance herself between the two demands of
inventiveness and familiarity
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