1,720,970 research outputs found
Role of MR Spectroscopy (H1-MRS) of the Testis in Men with Semen Analysis Altered
Purpose:
Proton magnetic resonance spectroscopy (1 H-MRS) has been proposed as a tool to assess male
infertility providing metabolic signatures related to the spermatogenesis in the testis. This study sought to identify the
role of 1 H-MRS in the diagnosis of infertility in patients with semen analysis altered.
Materials and Methods:
14 patients (27 testicles) with fertility problems and with an altered semen analysis (5
oligospermia, 3 asthenospermia, 6 oligoasthenospermia) and 9 controls (18 testicles) with normal spermatogenesis
assessed (men with prior paternity and normal semen analysis) and normal testicles at magnetic resonance (MR)
and ultrasonography (US) with colour Doppler (CD) examination were included. All patients underwent testis US and
CD investigation, conventional MR examination at 1.5T including T1 and T2 weighted images in three orthogonal
planes and proton magnetic resonance spectroscopy (1 H-MRS) with single-voxel PRESS (TR 2000 ms / TE 31
ms). Major metabolites peaks (choline, creatine, lipids, lactate) were calculated and compared between the patients
and controls.
Results:
Mean choline peak in the semen analysis altered group was statistically significantly lower than the
normal group (0.69 vs 1.34, 95% CI: 0.52 - 0.85; p < 0.001). 18 testicles within semen analysis altered group
(66,7%) had both MR and US examination negative but mean choline peak lower then controls (1.09 vs 1.34, p <
0.001). 7 testicles of those presented also varicocele at CD investigation.
Conclusion:
1 H-MRS revealed a significant shift towards lower choline peak in patients with semen analysis
altered compared to controls with normal spermatogenesis. Moreover 1 HMRS provided to find out spermatogenesis
disorder in patients with normal testis at MR and US examination
Multi-Focal Endometriosis in a Young Woman with Adnexal Para-Mesonephric Cyst: Role of MRI in Surgical Planning
We present a case of a young woman with several cystic lesions of different origin in both ovaries. The MRI played
a crucial role for the pre-operative characterization of the lesions helping to define the possible malformative origin
of one of those then confirmed by the laparoscopy as hydatid of Morgagni in a multifocal endometriosis patient. A
discussion of the MR imaging findings is provided as follow
Extraosseus Ewing sarcoma: An uncommon periclavicular location
AbstractA rapidly enlarging right sternoclavicular mass in a young male was labeled as a nonspecific mass. MRI played a crucial role in characterizing the lesion, helping to define the possible mesenchymal origin and the relative involvement of the surrounding structures. We also discuss the differential diagnosis of an extraosseus Ewing sarcoma (ES), with its imaging findings
Ruolo dell'imaging termografico digitale ad infrarossi (DITI) e dell'ultrasonografia (US) nella sindrome da "colpo di frusta"
Scopo del lavoro è stato rilevare eventuali correlazioni tra DITI e US nei pazienti con sindrome da "colpo di frusta" per la valutazione del danno biologico ai tessuti molli del rachide cervico dorsal
Ruolo della Risonanza Magnetica Spettroscopica (1H-MRS) dei testicoli in pazienti con spermiogramma alterato
La 1H MRS del testicolo è stata proposta come indagine alternativa per studiare l'infertiliutà maschile attraverso l'analisi dei principali metaboliti correlati alla spermatogenesi. Si valuta il suo ruolo nei pazienti con spermiogramma alterato
Diagnostic Imaging of the Diffuse Hepatic Epithelioid Hemangioendothelioma's Type: A Case Report
We present the case of 35 years old female patient who came to our Institute with an unspecified abdominal pain,
hepatosplenomegaly and a previous alleged diagnosis of Budd-Chiari syndrome. Magnetic resonance imaging (MRI) was crucial to identify a diffuse and infiltrating mass involving the liver in a misleading diagnosis. A discussion about the imaging findings and differential diagnosis of a rare case of diffuse epithelioid hemangioendothelioma (EHE) is provided as follows. MRI was the most important instrument to guide the diagnostic and therapeutic path, helping to define the typical signal intensity of EHE, mainly with a hepatobiliary contrast agent. The differentiating between other primary tumors, however, remains a complicated issue. Our purpose was to highlight the radiologic and MR characteristics of this rare tumor in order to evaluate the diffuse EHE in the diagnostic process
Testicular Microlithiasis and Testicular Germ Cell Tumors: A Seven Year Retrospective Study
Purpose
To evaluate the association between grade II and III testicular Microlithiasis (TM) and Testicular Germ Cell Tumor (TGCT), reporting disease-free survival over 7 years.
Materials and Methods:
The association between TM and TGCT was studied in 7,320 male patients referred to the radiology department of an Italian hospital for several scrotal disease. TM associated with TCGT was diagnosed in all men by ultrasound (US) and by testicular histology specimens. All patients with TM were followed-up annually with US. Chi-square, Kaplan-Meyer and Fisher’s exact test were used for statistical analysis.
Results:
The incidence of TM was 1.4% (98 of 7320). Twenty eight patients with TGCT (28 of 58, 48.2%) had associated TM. During the follow-up, testicular cancer was detected in six patients (incidence 6.12%, 95%
confidence interval from 2.8 to 12.7); four of these were recurrences of TGCT, while the other two patients were
ex novo TGCT. There was a significant difference (p < 0.001) between the rate of TGCT in men with TM (28 of 98,
28.5%) and that in men without TM (30 of 7222, 0.4%) with an odds ratio of 95.89 [95% CI 42.7 - 110.5].
Conclusion:
The association found between TGCT and TM addresses microlithiasis as a prospective marker for testicular tumor. Yearly follow-up with US should be taken into consideration, encouraging self-examination in the meantime
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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