1,721,404 research outputs found
Complexation Stabilized Conformational Regulation of Ferrocene Bearing Podand Dipeptide Chains (-l-Ala-l-Pro-NHPy)
No full textThe structural characterization of the palladium complex of the ferrocene 1 bearing podand
dipeptide chains (-l-Ala-l-Pro-NHPy) was demonstrated. The ferrocene 1 forms the 1:1 trans
complex 2 with PdCl2(MeCN)2 to stabilize the intramolecular conformational regulation in
both solution and solid states. The crystal structure of 2 revealed a pseudohelical
conformation through palladium binding and chirality organization via sterically constrained
moieties (Pro) and intramolecular hydrogen bondings between CO (Ala) and NH (another
Ala) of each podand dipeptide chain (N(1)···O(2*), 2.88 Å; N(1*)···O(2), 2.97 Å), giving a
10-membered hydrogen-bonded ring. Such an ordered conformation was supported by the
induced circular dichroism. Another noteworthy feature of the ferrocene 1 is its strong
tendency to self-assemble through participation of all available hydrogen-bonding donors
in the solid state
Complexation Stabilized Conformational Regulation of Ferrocene Bearing Podand Dipeptide Chains (-l-Ala-l-Pro-NHPy)
No full textThe structural characterization of the palladium complex of the ferrocene 1 bearing podand
dipeptide chains (-l-Ala-l-Pro-NHPy) was demonstrated. The ferrocene 1 forms the 1:1 trans
complex 2 with PdCl2(MeCN)2 to stabilize the intramolecular conformational regulation in
both solution and solid states. The crystal structure of 2 revealed a pseudohelical
conformation through palladium binding and chirality organization via sterically constrained
moieties (Pro) and intramolecular hydrogen bondings between CO (Ala) and NH (another
Ala) of each podand dipeptide chain (N(1)···O(2*), 2.88 Å; N(1*)···O(2), 2.97 Å), giving a
10-membered hydrogen-bonded ring. Such an ordered conformation was supported by the
induced circular dichroism. Another noteworthy feature of the ferrocene 1 is its strong
tendency to self-assemble through participation of all available hydrogen-bonding donors
in the solid state
KONSEP D{ALA>L DALAM AL-QUR’AN (Kajian Semantik al-Qur’an)
Full text linkTesis dengan Judul “KONSEP D{ALA>L DALAM AL-QUR’AN (Kajian Semantik al-Qur’an)” ini ditulis oleh Ahmad Saddad, 175315002, dibimbing oleh Dr. Ahmad Zainal Abidin, MA, dan Dr. Salamah Noorhidayati, M. Ag.
Kata Kunci: D{ala>l, Semantik al-qur’an.
Penelitian dalam Tesis ini dilatarbelakangi oleh pengamatan penulis terhadap adanya sikap truth claim di kalangan internal kaum muslim, sehingga kelompok tersebut menganggap kelompok muslim lain sebagai sesat. Hal tersebut tentu akan berimplikasi pada terpecah belahnya umat. Istilah sesat dalam bahasa Arab sering ditujukan pada term d{ala>l, dan dalam al-qur’an term tersebut terulang 191 kali. Dalam Qs. al-D{uh{a ayat 7, Nabi Muhammad disebut-sebut sebagai d{ala>l, demikian pula dalam Qs. al-Syu’ara>’ ayat 20, nabi Musa as mengatakan dirinya d{ala>l. Hal tersebut menarik untuk diteliti dengan menggunakan pendekatan semantik. Sehingga dapat diketahui pandangan dunia (weltanscahuung) al-qur’an tentang d{ala>l.
Rumusan masalah dalam tesis ini adalah: 1) bagaimana makna dasar dan makna relasional kata d{ala>l? 2) Bagaimana perkembangan makna d{ala>l ditinjau dari aspek sinkronik dan diakroniknya?Sedangkan tujuan dari penulisan tesis ini adalah untuk mengetahui makna dasar dan makna relasional kata d{ala>l, begitu pula perkembangan maknanya baik dari sisi sinkronik maupun diakronik, sehingga bisa terungkap bagaimana pandangan dunia (weltanscahuung) al-qur’an tentang d{ala>l.
Jenis penelitian Tesis ini adalah studi kepustakaan (library research) dengan sumber data terbagi menjadi dua, yaitu 1) sumber data primer yakni al-qur’an, di>wa>n yang memuat syair-syair Arab Jahili, dan kitab-kitab tafsir. 2) sumber data sekunder yakni setiap buku, tesis, skripsi, atau artikel yang menjadikan semantik sebagai fokus kajiannya. Teknik pengumpulan data dengan menginventarisasi data yang diperoleh dari sumber primer maupun sumber sekunder. Sementara teknik analisa data yang digunakan adalah analisis semantik.
Penelitian ini menyimpulkan: 1) makna dasar d{ala>l adalah hilang, sementara makna relasionalnya menunjuk beberapa arti: a) bermakna sesat manakala: i) diiringi kata kufr, syirk, muna>fiq, z{a>lim, dan fa>siq, ii) diiringi mubi>n, ba’i>d, dan kabi>r, iii) diiringi kata syait{a>n, dan hawa>’. b) kekeliruan, saat membincang orang-orang saleh. c) lupa, saat membincang masalah persaksian. D{ala>l memiliki beberapa padanan kata yakni gayy, gaflah, zaig, t{ugya>n, dan ‘amhan, sementara lawan katanya adalah huda>. 2) Perkembangan makna d{ala>l ditinjau dari aspek sinkronik diakronik menunjuk pada tiga periode. a) periode pra qur’anik menunjuk pada kondisi kerugian, kemalangan, dan kesia-siaan. b) periode qur’anik membawa makna d{ala>l pra qur’anik menuju makna religius. c) Periode pasca qur’anik d{ala>l mengalami penyempitan makna, yakni takfir dan bid’ah
The Mode of Action of Cyclo(l-Ala-l-Pro) in Inhibiting Aflatoxin Production of Aspergillus flavus
No full textCyclo(l-Ala-l-Pro) inhibits aflatoxin production in aflatoxigenic fungi without affecting fungal growth. The mode of action of cyclo(l-Ala-l-Pro) in inhibiting aflatoxin production of Aspergillus flavus was investigated. A glutathione S-transferase (GST) of the fungus, designated AfGST, was identified as a binding protein of cyclo(l-Ala-l-Pro) in an experiment performed using cyclo(l-Ala-l-Pro)-immobilized Sepharose beads. Cyclo(l-Ala-l-Pro) specifically bound to recombinant AfGST and inhibited its GST activity. Ethacrynic acid, a known GST inhibitor, inhibited the GST activity of recombinant AfGST and aflatoxin production of the fungus. Ethacrynic acid reduced the expression level of AflR, a key regulatory protein for aflatoxin production, similar to cyclo(l-Ala-l-Pro). These results suggest that cyclo(l-Ala-l-Pro) inhibits aflatoxin production by affecting GST function in A. flavus, and that AfGST inhibitors are possible candidates as selective aflatoxin production inhibitors
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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