47,360 research outputs found
ADAM SMITH'S OPTIMISTIC TELEOLOGICAL VIEW OF HISTORY
No full textAdam Smith's four-stage theory provides the framework for his writings on history. The fourth stage is the commercial epoch; the culmination of history in this stage is a key component in the conventional interpretation of Adam Smith as a prophet of commercialism. In two historical case studies Smith shows the capacity of commercial society to regenerate itself. This potent capacity suggests that commercial society is inevitable. At a certain point in time it also overcomes the major obstacles to its permanence. Smith's philosophy of history anticipates the end of history views of Kant and Hegel.Political Economy,
Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature
No full textHuman polymorphonuclear leukocytes adhesion to endothelial cells during the early stage of inflammation leads to cell surface externalization of Annexin A1 (AnxA1), an effector of endogenous anti-inflammation. The antiadhesive properties of AnxA1 become operative to finely tune polymorphonuclear leukocytes transmigration to the site of inflammation. Membrane bound proteinase 3 (PR3) plays a key role in this microenvironment by cleaving the N terminus bioactive domain of AnxA1. In the present study, we generated a PR3-resistant human recombinant AnxA1-named superAnxA1 (SAnxA1)-and tested its in vitro and in vivo properties in comparison to the parental protein. SAnxA1 bound and activated formyl peptide receptor 2 in a similar way as the parental protein, while showing a resistance to cleavage by recombinant PR3. SAnxA1 retained anti-inflammatory activities in the murine inflamed microcirculation (leukocyte adhesion being the readout) and in skin trafficking model. When longer-lasting models of inflammation were applied, SAnxA1 displayed stronger anti-inflammatory effect over time compared with the parental protein. Together these results indicate that AnxA1 cleavage is an important process during neutrophilic inflammation and that controlling the balance between AnxA1/PR3 activities might represent a promising avenue for the discovery of novel therapeutic approaches
Cloning, purification and characterisation of human and mouse ADAM 8 sheddase activity
No full textAl-Riyami H. Cloning, purification and characterisation of human and mouse ADAM 8 sheddase activity. Bielefeld (Germany): Bielefeld University; 2006
How Might Adam Smith Pay Professors Today?
No full textAdam Smith’s proposal for paying professors was intended to induce increased faculty knowledge. If students have imperfect information about what they learn, and universities can only imperfectly measure the input of faculty time in student learning, publications may be used to measure faculty knowledge. If professors’ ability to publish is positively related to their ability to produce student learning, which universities can imperfectly measure, publications may be necessary to attract more able professors. Since research signals faculty knowledge, schools that do not value publications per se could require higher publication standards and pay higher wages than schools that value only publications.
ADAM SMITH'S VIEW OF HISTORY: CONSISTENT OR PARADOXICAL?
No full textThe conventional interpretation of Adam Smith is that he is a prophet of commercialism. The liberal capitalist reading of Smith is consistent with the view that history culminates in commercial society. The first part of the article develops this optimistic interpretation of Smith's view of history. Smith implies that commercial society is the end of history because 1) it supplies the ends of nature that he identifies; 2) it is inevitable; and 3) it is permanent. The second part of the article shows that Smith has some dark moments in his writings where he seems to reject completely such teleological notions. In this more civic humanist mood he confesses that commercial society does not supply the ends of nature, nor is it inevitable, nor is it permanent. Both views exist in Smith and the commentator is forced to choose between passages in Smith's work in order to support a particular interpretation of the former's view of history.Political Economy,
Sejarah islam : sejak zaman nabi adam hingga abad xx tahun 2003
No full textBuku sejarah islam ini membicarakan tentang sejarah masa lampau, sejak zaman nabi adam as. yang diturunkan oleh Allah swt. ke dunia, lalu berlanjut dengan kisah para nabi yang mulia.xiii, 566 hlm, 21,6 x 14,2 c
Adam Smith and Roman Servitudes
No full textThis essay is a preprint of an article that appeared at: Tijdschrift voor Rechstsgeschiedenis, 72 (2004), 327–57.This essay discusses Adam Smith historical jurisprudence and his use of Roman law materials in his Lectures on Jurisprudence. It argues that Smith found it difficult to maintain his theory of legal development in the face of a highly developed body of Roman law literature
An evalution of the use subject based information gateways: case Study ADAM
No full textNowadays, end-users have quick and direct access to a massive amount of information available on the net. However, this information is unorganised expecting users to be able to identify and evaluate it in accordance with their information needs. Subject Based Information Gateways (SBIGs), organised collections of networked information, provide users with a catalogue of authoritative Internet resources, which can be searched or/and browsed. This paper provides an evaluation of one such gateway - the Art, Design, Architecture & Media Gateway (ADAM). It provides information on who these digital users are, how often they use the service, what their reasons for use are, which search methods and services provided they prefer, and what are the advantages and/or disadvantages of an online information service
The Black Londoner Experience: Exploring Black Life through Records of the Court, 1720-1840
No full textBlack Londoners have lived in the city for centuries. This collection brings 10 Black London lives together in an accessible volume to share the diversity of their experiences in the eighteenth and early nineteenth centuries with new readers.
Drawing on the records of the Old Bailey criminal courthouse, these ten carefully selected trials have been chosen to show some of the breadth of Black experience in London during the age of enslavement (c. 1720-1840). The volume includes Black victims, witnesses, and defendants; men, women, and children; sailors, servants, and entertainers; locals, immigrants, and visitors. Some were treated well by the justice system, and others were met with cruelty. Each had their own experience.
While the volume contains details of crime and conflict, crime is not the sole focus. The sources also give us glimpses into the daily lives of these Black individuals as they interacted with the city and its inhabitants. We learn where these Black people spent their time, with whom, doing what, and sometimes even what they had in their pockets.
Each of the ten cases has been accessibly formatted for classroom use or personal study, and features illustrations by Manon Wright. The sources are arranged like plays, making them easy to read aloud as a means of better understanding the theatre of the courtroom and the power dynamics at play. Dr Crymble offers notes and reflections on tricky or foreign concepts in each case, as well as issues that he has noted through experience that students often misinterpret by making modern assumptions about the past.
John Humphreys, 1727
John Cross, 1749
Elizabeth Gift, 1755
Esther Allingham, 1782
John Thomas, 1786
James Wallis, 1801
Dolby Jackson, 1808
Thomas Johnson, 1818
'The Busker' 1831
Louis James Grant, 1840
For serious scholars of Black experience in 18th/19th century London criminal records, the author also recommends the following works:
Tim Hitchcock, Robert Shoemaker, Clive Emsley, Sharon Howard, Jamie McLaughlin, et al, the Old Bailey Proceedings Online, 1674-1913 (www.oldbaileyonline.org, version 8, 2018.
Adam Crymble and Emma Azid, 'Black Lives, British Justice: Black People in London Criminal Justice Records, 1720-1841' Journal of Slavery and Data Preservation vol. 2, no 2. (2021): 1-11.
Kathleen Chater. Untold Histories: Black People in England and Wales during the Period of the British Slave Trade, c. 1660-1807 (Manchester, 2011).
Norma Myers, Reconstructing the Black Past (Frank Cass, 1996).
Marika Sherwood. ‘Blacks in the Gordon Riots’, History Today, vol. 47 (1997), 24-28
- …
