196,874 research outputs found
Anti-Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre-Clinical Evidence
No full textOtitis media (OM), a common infection of the middle ear, remains a leading cause of preventable hearing loss globally. Chronic inflammation underpins its pathophysiology, driving persistent mucosal damage and complications such as cholesteatoma. Key inflammatory mediators contribute to sustained neutrophilic infiltration and mucosal thickening, making them attractive therapeutic targets. Flavonoids, a diverse group of hydroxylated polyphenols with established anti-inflammatory and antioxidant properties, have shown efficacy in a range of diseases, including cancer, metabolic disorders, and neurodegeneration. However, their potential role in modulating inflammation in OM has not been systematically explored. Here, we conducted a systematic review of rodent models of OM treated with flavonoids, adhering to PRISMA guidelines and searching PubMed, Scopus, Cochrane, MEDLINE, and CINAHL Complete. Outcomes included serum and mRNA expression of TNF-α, IL-1β, IL-4, IL-6, and VEGF, as well as neutrophil counts and mucosal thickness. Across studies, flavonoid treatment was associated with downregulation of pro-inflammatory markers, reduced neutrophilic infiltration, and attenuation of mucosal thickening. These findings highlight the potential of flavonoids as adjunctive agents in OM, warranting further investigation into their mechanistic pathways and translational relevance.Full Tex
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
Characteristic study of the internal target for the Double Hypernuclei physics at PANDA
No full textThe case of the internal target for the hypernuclear experiment of the PANDA (antiproton Annihilation at Darmstadt) Collaboration at the HESR (High Energy Storage Ring) of FAIR (Facility for Antiproton and Ion Research) is illustrated. The main aspects of the experiment designed for the production of Double Hypernuclei are initially summarized. The problems arising from the interaction of a solid internal target with an antiproton beam inside a ring are briefly discussed, together with the constraints in making such a set up. The design of material, shape and size of a target satisfying the experimental requirements is presented. The techniques used to produce a prototype of this target are illustrated. Then the results of the tests performed on the prototype to investigate the properties (purity, radiation hardness, structure modifications after shaping) are reported and the plan of the future activity is presented
Simulation of thermal plant optimization and hydraulic aspects of thermal distribution loops for large campuses
No full textFollowing an introduction, the author describes Texas A&M University and its utilities system. After that, the author presents how to construct simulation models for chilled water and heating hot water distribution systems. The simulation model was used in a $2.3 million Ross Street chilled water pipe replacement project at Texas A&M University. A second project conducted at the University of Texas at San Antonio was used as an example to demonstrate how to identify and design an optimal distribution system by using a simulation model. The author found that the minor losses of these closed loop thermal distribution systems are significantly higher than potable water distribution systems. In the second part of the report, the author presents the latest development of software called the Plant Optimization Program, which can simulate cogeneration plant operation, estimate its operation cost and provide optimized operation suggestions. The author also developed detailed simulation models for a gas turbine and heat recovery steam generator and identified significant potential savings. Finally, the author also used a steam turbine as an example to present a multi-regression method on constructing simulation models by using basic statistics and optimization algorithms. This report presents a survey of the author??s working experience at the Energy Systems Laboratory (ESL) at Texas A&M University during the period of January 2002 through March 2004. The purpose of the above work was to allow the author to become familiar with the practice of engineering. The result is that the author knows how to complete a project from start to finish and understands how both technical and nontechnical aspects of a project need to be considered in order to ensure a quality deliverable and bring a project to successful completion. This report concludes that the objectives of the internship were successfully accomplished and that the requirements for the degree of Degree of Engineering have been satisfied
Unpacking choices: a study on food package information use among wellness seekers and those managing long-term illnesses
No full textIntroduction: Nutrition labels were designed to help consumers choose foods according to their health status. Detailed nutritional tagging is essential to help buyer be informed about the component of the food and enabling consumers to make healthy choices according to their health status. Therefore, this study aims to assess and compare usage nutrition labels among healthy individuals and individuals with chronic diseases.
Methodology: A validated questionnaire was used to collect data from the sample of 410 participants through convenient sampling technique. Subjects recruited were healthy individuals and individuals with chronic diseases, aged ≥ 18 years. Version 20 of SPSS was used to analyzed the obtained data. Chi square test (level of significance 0.05) was used to determine the current knowledge and usage of food and nutrition labels among study participants.
Results: The results revealed that majority of the study participants (52%) were healthy, while (48%) are diagnosed with chronic disease. Additionally, results show that 85% individuals with chronic diseases read food and nutrition label. However, on contrary statistically no significant difference was identified (p = 0.192) in usage of nutritional labels among healthy individuals and individuals with chronic diseases.
Conclusion: The usage of food label and nutrition facts information is common among population and the information consumers focus on food and nutrition labels is halal certification and date of expiry.Full Tex
Understanding Psychological Connections to Dietary Behavior: A Study of Future Medical Professionals' Knowledge and Insights
No full textBackground: Eating disorders are not a lifestyle of choice rather illnesses that are of serious concern. Eating disorders pose a huge global burden. Body dissatisfaction, overweight in childhood and various other factors has increased the risk of having eating disorders. Different studies conducted in Pakistan conclude that a significant fraction of medical university students is at risk of having Eating Disorders. Methods: A cross-sectional study was conducted among 834 participants from Dow medical college and Dow international medical of Karachi. Participants of the study were recruited through convenient sampling technique, by signing an informed consent. Data was collected using self-administered questionnaire, which included 26 items in total. Initial questions were about the demographic details of the participants and there were twenty questions to assess participants’ knowledge about eating disorders. This data was analyzed and presented using SPSS version 16 along with Office word format and excel. Results: Overall, the average number of correct responses to eating disorders terminology and characteristics related questions was 6.88 ± 1.94 (out of 10 questions). Mean score for knowledge about eating disorders assessment and terminology was 6.55 (out of 10 questions) with a standard deviation of ±1.68. Participants’ sex, age, and level of education were found to be significantly associated with their knowledge about eating disorders. Conclusion: Eating disorders are serious medical conditions, yet students lack adequate understanding regardless of gender or university. While higher study levels show a slight positive impact, attention must be given to curriculum, teaching hours, and clinical exposure for eating disorders.Full Tex
Intern experience at CH���M Hill, Inc.: an internship report
No full textIncludes author's vita"Submitted to the College of Engineering of Texas A&M University in partial
fulfillment of the requirement for the degree of Doctor of Engineering."Includes bibliographical referencesA review of the author's internship experience with CH���M HILL, Inc.
during the period September 1975 through May 1976 is presented. During this nine month
internship the author worked as an Engineer II in the Industrial Processes discipline of this
large consulting engineering firm... The author's prime responsibility was as one of three
lead design engineers on the design of a large wastewater treatment facility for a pulp mill
in Hoquiam, Washington owned by ITT Rayonier Inc. The work generally consisted of the design
of individual treatment units and associated piping and pumping. The purpose of the project
was to provide wastewater treatment capabilities that would satisfy the effluent limitations
(standards) imposed upon the mill by the State of Washington Department of Ecology and the
U.S. Environmental Protection Agency. The author's assignment also entailed necessary
interaction with the project manager and other CH���M HILL design engineers and support staff
members, the client's representatives, and representatives of two other consulting engineering
firms working on the project. Thus, the internship position at CH���M HILL provided considerable
experience coordinating the author's work with the work of other engineers, guiding the design
and administrative efforts of a support staff, and interacting regularly with the client and
other consulting firms. This broad exposure to a variety of engineering and organizational
problems provided a valuable educational experience
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