212 research outputs found

    Implementation of “Make a Match” Type of Cooperative Learning Model Assisted With Student Worksheets (Lkpd) to Improve VII Grade Students' Learning Competences in Natural Science Subject in SMPN 5 Padang

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    The purpose of the research was to know the improvement of students' cognitive competence in learning IPA by implementing “make a match” type of cooperative learning model assisted by student worksheets (LKPD) in SMPN 5 Padang. This research was a Classroom Action Research. It consisted of two cycles. Each cycle included planning, acting, observing and reflecting stages. The subject of the research was 32 students of grade VII7 in SMPN 5 Padang in academic year 2017/2018. The instruments used were students' test, camera recordings and field notes. The data of the research were analyzed in descriptive qualitative method.The research finding showed that the implementation of “make a match” type of cooperative learning model assisted by LKPD can improve students' cognitive competences from cycle I to cycle II. The percentage of cognitive competence mastery in cycle I was 78% (good enough). Meanwhile, in cycle II, the percentage of cognitive competence mastery was 94% (very good). So, it can be concluded that through implementing “make a match” type of cooperative learning model assisted by LKPD, it can improve VII7 grade students' cognitive competences in learning IPA in SMPN 5 Padang

    An Analysis of Scientific Literacy of Students of SMPN 4 Tanjung Pinang and of SMPN 6 Tanjung Pinang

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    This study aimed to describe the results of the analysis of scientific literacy skills of students of SMPN 4 Tanjung Pinang and SMPN 6 Tanjung Pinang. This research is descriptive research. The technique of sampling was purposive sampling. The data collection technique used the PISA scientific literacy questions of 2015 and was supported by interviews between students and a teacher. The data analysis technique was carried out by calculating the average value of the students’ scientific literacy test results. The technique of checking the validity of the data used triangulation. The results showed that the achievement of students’ scientific literacy was in the low category. The conclusion of this study is the achievement of the result of the scientific literacy test of students of SMPN 4 Tanjung Pinang and SMPN 6 Tanjung Pinang based on the total score showed that the ability of students of SMPN 4 Tanjung Pinang in answering scientific literacy questions is higher than the students of SMPN 6 Tanjung Pinang

    An Analysis of the Biological Learning Quality of Grade X Sman Unggul, Dharmasraya, Assessed from the Teachers and the Student Aspects

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    This study was aimed at analyzing the biological learning based on the Minister of Education Regulation No. 41 of 2007 concerning the standard of the educational process which includes planning, implementation, and assessment of learning in grade X SMAN Unggul Dharmasraya. This study was a descriptive study with a qualitative approach. The informants of this study were the biology teachers of grade X, deputy headmasters and students of grade X MIPA SMAN Unggul Dharmasraya. The data collection techniques used in this study were interviews, study documentation, observation, recording of the learning process. The instruments used were interview sheets and assessment sheets adopted from UNP 106 area PLPG Learning Implementation Assessment Instrument, observation sheets, interview sheets, camcorders, and field notes. The data analysis technique in this study was quantitative data in the form of numbers obtained from the RPP assessment sheet and observation sheet analyzed by using statistical calculations. The data obtained from observations, documentation studies, interviews were processed by describing and analyzing the data until conclusions were obtained. The results of this study indicated that the planning made by the teachers obtained low result. The implementation of learning carried out received on the low criteria, as well as the assessment conducted by the teachers obtaining on the low criteria. Furthermore, the teachers had problems in terms of knowledge of planning making that fits the K13 curriculum. In the implementation of learning the teachers had not fully understood in applying the recommended learning model in the K13 curriculum. In terms of assessment the teachers did not carry out an affective and psychomotor assessment because the instruments were too many and the teachers did not know it. Thus, from this study it can be concluded that the process of the biology learning in grade X SMAN Unggul Dharmasraya is not appropriate with Minister of National Education No.41 of 2007 concerning the standard of the education process

    Validity of Student Work Sheet Based Guided Inquiry on Learning Materials of Organism Classification and Life Organization for MTs Students Grade VII

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    Curriculum is an educational response to societies’ and nations’ needs in developing young generation. The curriculum gives a significant contribution to bring the development process of students’ potential in learning into reality. Learning of Science (IPA) emphasizes on the ability to do scientific inquiry to raise cognitive, affective, and communicative skills. IPA includes four main elements: attitude, process, product, and application. IPA learning process is expected to raise those four elements so that students can experience the whole learning process, and it can be used to solve life’s problems.  It can be reached by applying one learning model, that is ‘guided inquiry learning model’. The learning process cannot also apart from learning materials. One of the materials is student work sheet, which is able to improve students’ skill process. The aim of the research was to develop student work sheet based guided inquiry for MTs students grade VII and to validate its criteria. The research was a development research using Plomp model. The Validity of student work sheet based guided inquiry was obtained from the result of expert validity sheets done by four experts. The result of this research showed that in didactic aspect got 77,08% with the criteria was valid, construct aspect got 90% with very valid criteria, technical aspect got 85,93% with the criteria was very valid, and the average of these three aspects got 84,33% with the criteria was very valid. Student work sheet based guided inquiry was successful to be developed by validity criteria, which was very valid. Then, it is expected that it can be a qualified and innovative learning material to help improve students’ learning competence

    Detection of p53 germline mutation in Li-Fraumeni syndrome families

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    Li-Fraumeni syndrome is an autosomal dominant familial cancer syndrome that in its classic form is defined by the existence of both a proband with a sarcoma and two other first-degree relatives with a cancer by age 45 years. Approximately 70% of families with LFS is caused by p53 gene mutation. P53 mutant could not do its normal function to arrest at G1 phase of cell cycles or to induce the cell death program via apoptosis after DNA damage and thereby may attempt replication of damaged genome. This activity suggests that cells with mutant p53 will accumulate further mutations more rapidly and display increases genomic instability. This condition is consistent with the increased neoplastic potential of patients with Li-Fraumeni syndrome who inherit a germ line defect in one p53 allele.Sequencing technique is a rapid detection procedure has been developed to detect the p53 germ line mutation in Li-Fraumeni syndrome family, but because it is so labor intensive, large-scale screening tests are impractical. Some alternative techniques have been developed like functional screening test of p53 mutation based on the loss of wild type transcription activation and single strand conformation polymorphism mutation analysis based on the differences of single strand DNA migration pattern on polyacrylamide gel

    Detection of p53 germline mutation in Li-Fraumeni syndrome families

    No full text
    Li-Fraumeni syndrome is an autosomal dominant familial cancer syndrome that in its classic form is defined by the existence of both a proband with a sarcoma and two other first-degree relatives with a cancer by age 45 years. Approximately 70% of families with LFS is caused by p53 gene mutation. P53 mutant could not do its normal function to arrest at G1 phase of cell cycles or to induce the cell death program via apoptosis after DNA damage and thereby may attempt replication of damaged genome. This activity suggests that cells with mutant p53 will accumulate further mutations more rapidly and display increases genomic instability. This condition is consistent with the increased neoplastic potential of patients with Li-Fraumeni syndrome who inherit a germ line defect in one p53 allele.Sequencing technique is a rapid detection procedure has been developed to detect the p53 germ line mutation in Li-Fraumeni syndrome family, but because it is so labor intensive, large-scale screening tests are impractical. Some alternative techniques have been developed like functional screening test of p53 mutation based on the loss of wild type transcription activation and single strand conformation polymorphism mutation analysis based on the differences of single strand DNA migration pattern on polyacrylamide gel

    FOLLICLE STIMULATING HORMONE RECEPTOR Ser680Asn POLYMORPHISM IN WOMEN WITH POLYCYSTIC OVARY

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    Polymorphisms at codon 680 (Ser680Asn) of FSH receptor gene affected the basal FSH levels and sensitivity of FSH receptor to FSH exogenous in women undergoing assisted reproduction program in some ethnics in the world, while it could not proved in others. This study aims to determine the association of polymorphisms Ser680Asn in patients with polycystic ovary (PCO) in Indonesian population. The study involved 30 PCO patients and 30 normal women. Polymorphisms analysis was performed by PCR - RFLP. ELISA was used to detect FSH level. Statistical analysis was done by chi - square and t tests. This study shows the homozygote variant Ser/Ser is significantly different in distribution between patients and normal women where it is more frequent in PCO women. In normal women, the three allelic variant distributed normally. There is no significant different in FSH level in three genotipe between patients and normal women. Conclution: There is a significant different in genotype distribution of FSH receptor gene between PCO patients and normal women for polymorphism at codon 680 but it was not associated with FSH level

    Effect of Learning Model Discovery of Competence Student Subject Biology Class VIII MTSN Rambah 2014/2015 Academic Year

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    The play the caused of this study arose from the low of students' cognitive competence. In addition, the affective and psychomotor competences were never been assessed. This can be seen from the number of student exam scores who Achieved under the Minimum Standard Criteria. The purpose of this study was to Determine Whether student learning using discovery learning competence is better than conventional models of learning. This study used quasi-experimental with randomized control-group posttest only design. This study was conducted from January to April 2015. The Cognitive Data were Obtained by using the test, while affective and psychomotor Data were Obtained by using observation sheet. The statistical tests for the first hypothesis is T-test whereas for the second and third hypotheses use Mann Whitney U tests. The results Showed discovery learning models that can improve student learning outcomes. For the first hypothesis, it was Obtainedthat tobserved is 3,206. While for the second and third hypothesis, they were Obtained aspectis 0000 that the affective and the psychomotor aspectis 0001 for sig. Based on the results of the study, it can be concluded that teaching students with learning discovery Significantly, the model is better than the conventional learning models at MTsN Rambah in 2014/2015 academic year

    Implementation of Guided Inquiry Learning Models Aid of LKS to Improve the Competency of Learning Science Biology in Class VIII.D MTsN Padang Panjang

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    Completeness of learning is closely related to the learning process that occurs in schools. The involvement of students as a whole in the learning process affects the ability of students to remember the material being studied, which affects the knowledge, understanding, and skills of students. Inquiry learning is a learning model that encourages students to learn mostly through active involvement with the concepts and principles of conducting experiments that allow them to discover principles for themselves. The purpose of this study was to improve the students' competency in learning science in the affective, psychomotor, and cognitive domains of class VIII D MTsN Padang Panjang through the application of guided inquiry learning models. The research method applied is a classroom action research method with the research subjects of class VIII D MTsN students in the 2015-2016 school year. The percentage of pre-cycle affective competence was 56.21%, cycle I was 78.22%, and cycle II was 88.45%. The percentage of pre-cycle psychomotor competence was 71.88%, the first cycle was 81.94%, and the second cycle was 90.28%. The percentage of pre-cycle cognitive competence was 64.88%, the first cycle was 77.06%, and the second cycle was 80.15%. These data show that the application of guided inquiry learning models assisted by student worksheets can improve students' competency in learning Biology Science
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