12 research outputs found
Simulation based Analysis of Transformerless Photovoltaic Inverter Topologies for Reactive Power handling Capability
No full textThis study investigates the reactive power generation capability of the existing transformerless Photovoltaic Inverter Topologies (PVIT) with their conventional switching strategies. The topologies such as H5, families of H6 (H6, H6-I, H6-II, H6-III and H6-IV), HERIC, and clamped topologies (optimized H5, passive clamped H6 and HBZVR) have been selected for analysis. Matlab/Simulink simulation platform is employed for the analysis of PVIT. It has been observed that transformer-less PVIT with their conventional switching strategies are not suitable for reactive power injection. These topologies are generating highly distorted current at zero crossings during the reactive power flow. The improved switching strategies are needed to make these topologies suitable for the reactive power applications without any modification in the structure of the inverter.Accepted author manuscriptPhotovoltaic Materials and DevicesIntelligent Electrical Power Grid
Differential Partitioning of Betalains Using Aqueous Bi-Phasic Systems
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Folklore Elements in Vallikannan Novels
No full textFolk literature is created by the common people and preserved by them. Vallikannan is a renowned writer, journalist and author of all kinds of literature, his novels Iruttu Raja, Ninaivu charam and Oruveetin Kathi describe the life of Saiva Velalar in Nellai district in a rustic form. Among these games children's games are swinging, playing Tayakkatam, playing by singing and dancing, playing pandi, and playing Kannambuchi. Other common games are folk songs, titling, calling women by their village names, proverbs, folk performances related to religion, celebrating festivals, paying tribute to the village temple during festivals, performing arts, naming, marriage, processions, performing arts programs at weddings. They use figure of speech in their speech. The folk songs, proverbs and local idioms used by the Nellai district people reveals the author's general knowledge and approach to the people. It can be seen that the folk elements found in lullabies, folk tales, songs, stories, fables, myths, proverbs etc are mixed with the character and sentiment of the Tamil people. The article is about the folklore elements found in Vallikannan novels
Position Statement on Secukinumab in the Management of Plaque Psoriasis: The Malaysian Perspective
No full textPsoriasis is a chronic inflammatory skin disease affecting nearly 10% of dermatologic patients in Malaysia. Treatment options include topical agents and phototherapy as well as nonbiologic and biologic systemic therapy. Mild psoriasis can often be managed with topical agents. However, managing moderate to severe psoriasis is more challenging and may require systemic treatment with nonbiologics or biologics. Despite the availability of several biologics, there are many unmet clinical needs, which may be addressed by secukinumab, an IL-17A inhibitor. This position statement is based on an expert panel discussion and is intended to provide dermatologists an overview of existing options as well as to provide a better understanding of secukinumab and how it can be integrated into current practice. During the discussion, panel members examined current approaches and the role of secukinumab in plaque psoriasis management. Panel members estimated that up to 30% of patients have moderate to severe psoriasis but only 1-2% receive biologics. Highlights from the discussion were that (i) the threshold for biologic use should be lower, in line with international guidelines; (ii) studies have shown that secukinumab has several advantages over other biologics which are greater efficacy, sustained efficacy over time, rapid onset of action, and early evidence of possible disease-modifying potential; and (iii) ideal candidates for secukinumab are all patients of moderate to severe psoriasis, including those with history of treatment failure, difficult-to-treat patterns of psoriasis (nail, scalp, and palmoplantar psoriasis), psoriatic arthritis, and comorbidities and those aiming for clear skin. Panel members recommend that secukinumab be considered first line option among biologic therapies
Do diamide insecticides have any impact on beneficial arthropods? A review
No full textDiamide insecticides with novel modes of action have taken a significant place in modern agricultural practices around the globe due to their excellent toxicological profile and effective target efficiency against crop pests. However, concerns surrounding their impact on non-target organisms, particularly beneficial insects, have spurred widespread scrutiny. In this review, we extensively examine the off-target effects of diamide insecticides on demographic and life table parameters of insect pollinators, predators, parasitoids, and other beneficial organisms by understanding the mode of action as well as the critical comparison of the route of exposure of diamide insecticides between insect pests and beneficial arthropods. Furthermore, the differential susceptibility of different life stages of insects towards these insecticides, physiological impairment as well as detoxification mechanisms employed by natural enemies and pollinators to mitigate the adverse effects of diamide insecticides are also elucidated in detail. By critically evaluating the existing literature, it is clear that, while harnessing the benefits of diamides in insect pest management, the negative impacts on beneficial arthropods are not to be undermined. Future success in insect pest management will benefit from the identification of specific genes responsible for the detoxification of diamide pesticides in beneficial arthropods so as to harness the benefits, reduce their impact and sustain their presence in the global agrochemical market. Furthermore, policy regulations and outreach activities are needed to inform end users on the judicious use of diamides in specific crop ecosystems.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
From deterministic methods to a Bayesian approximation: towards reliable segmentation of multiple sclerosis Lesions in magnetic resonance imaging
No full textEn este trabajo, se presenta una metodología para la segmentación de lesiones de esclerosis múltiple (EM) en imágenes de resonancia magnética (IRM) que aborda las limitaciones de los modelos deterministas mediante la incorporación de la estimación de incertidumbre. Se compara una arquitectura U-Net 3D determinista con una versión modificada que emplea una aproximación bayesiana con Monte Carlo Dropout (MCD) para cuantificar la incertidumbre epistémica. Los resultados demuestran que, si bien ambos modelos alcanzan un rendimiento competitivo en términos de las métricas estándar de segmentación de imágenes médicas, la estimación de incertidumbre proporciona información valiosa sobre la fiabilidad de las predicciones, especialmente en regiones desafiantes como los bordes de las lesiones. Esto tiene el potencial de mejorar la aplicabilidad clínica de la segmentación automática al permitir a los usuarios médicos evaluar la confianza en los resultados y enfocar su revisión en áreas de mayor incertidumbre.In this work, we present a methodology for the segmentation of multiple sclerosis (MS) lesions in magnetic resonance imaging (MRI) that addresses the limitations of deterministic models by incorporating uncertainty estimation. We compare a deterministic 3D U-Net architecture with a modified version that employs a Bayesian approximation with Monte Carlo Dropout (MCD) to quantify epistemic uncertainty. The results demonstrate that while both models achieve competitive performance in terms of standard medical image segmentation metrics, the uncertainty estimation provides valuable information on the reliability of the predictions, especially in challenging regions such as lesion borders. This has the potential to improve the clinical applicability of automatic segmentation by allowing medical users to assess confidence in the results and focus their review on areas of higher uncertainty
The 2014-17 Global Coral Bleaching Event: The Most Severe and Widespread Coral Reef Destruction
No full textOcean warming is increasing the incidence, scale, and severity of global-scale coral bleaching and mortality, culminating in the third global coral bleaching event that occurred during record marine heatwaves of 2014-2017. While local effects of these events have been widely reported, the global implications remain unknown. Analysis of 15,066 reef surveys during 2014-2017 revealed that 80% of surveyed reefs experienced significant coral bleaching and 35% experienced significant coral mortality. The global extent of significant coral bleaching and mortality was assessed by extrapolating results from reef surveys using comprehensive remote-sensing data of regional heat stress. This model predicted that 51% of the world’s coral reefs suffered significant bleaching and 15% significant mortality, surpassing damage from any prior global bleaching event. These observations demonstrate that global warming’s widespread damage to coral reefs is accelerating and underscores the threat anthropogenic climate change poses for the irreversible transformation of these essential ecosystems.The U.S. National Oceanic and Atmospheric Administration’s (NOAA) Coral Reef Watch program and National Coral Reef Monitoring Program were supported by funding from the NOAA Coral Reef Conservation Program and Ocean Remote Sensing Program. University of Maryland and ReefSense personnel were fully supported by NOAA grant NA19NES4320002 (Cooperative Institute for Satellite Earth System Studies) at the University of Maryland/Earth System Science Interdisciplinary Center, and by the Professional, Scientific, and Technical Services Program (ProTech)-Satellite contract with Global Science & Technology, Inc. Funding for data collation and analysis provided by Vulcan Inc. The scientific results and conclusions, as well as any views or opinions expressed herein, are those of the author(s) and do not necessarily reflect the views of NOAA or the Department of Commerce. Figure 4 inspired by a National Geographic infographic [57]. We thank J. Moneghetti for assistance with statistical programming
