100,550 research outputs found
Copium clavicorne subsp. reyi W AGNER 1954
No full textCopium clavicorne reyi W AGNER, 1954 F R A F r a n k r e i c h: Midi-Pyrenees, Albi, 7 Ex., 16. VI. 1954, leg. Weber.Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 98, DOI: 10.5281/zenodo.750719
Antimicrobial Peptides, Infections and the Skin Barrier
No full textThe skin serves as a strong barrier protecting us from invading pathogens and harmful organisms. An important part of this barrier comes from antimicrobial peptides (AMPs), which are small peptides expressed abundantly in the skin. AMPs are produced in the deeper layers of the epidermis and transported to the stratum corneum, where they play a vital role in the first line of defense against potential pathogens. Numerous AMPs exist, and they have a broad antibiotic-like activity against bacteria, fungi and viruses. They also act as multifunctional effector molecules, linking innate and adaptive immune responses. AMPs play an essential part in maintaining an optimal and functional skin barrier - not only by direct killing of pathogens, but also by balancing immune responses and interfering in wound healing, cell differentiation, reepithelialization and their synergistic interplay with the skin microflora.</p
Precision measurement of the rovibrational energy-level structure of 4He+2
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Previous issue date: 6He is a three-electron system for which highly accurate textit{ab initio} calculations are possible._x000d_
The latest calculations of the rovibrational energies of He by Tung emph{et al.} footnote{W.-C. Tung, M. Pavanello and L. Adamowicz, textit{J. Chem. Phys.}, 136, 104309, 2012.} have a reported accuracy of 120 MHz, although they do not include relativistic and quantum electrodynamics (QED) effects. _x000d_
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We determined the rovibrational structure of He from measurements of the Rydberg spectrum of metastable He (He hereafter) and Rydberg-series extrapolation using multichannel quantum-defect-theory footnote{C. Jungen, textit{Elements of Quantum Defect Theory, in : Handbook of High-resolution Spectroscopy}, 2001.} footnote{D. Sprecher, J. Liu, T. Krähenmann, M. Schäfer, and F. Merkt, textit{J. Chem. Phys.}, 140, 064304, 2014.}._x000d_
He molecules are produced in supersonic beams with velocities tunable down to about 100 m/s by combining a cryogenic supersonic-beam source with a multistage Zeeman decelerator footnote{A. W. Wiederkehr, S. D. Hogan, M. Andrist, H. Schmutz, B. Lambillotte, J. A. Agner, and F. Merkt., J. Chem. Phys., 135, 214202, 2011.} footnote{M. Motsch, P. Jansen, J. A. Agner, H. Schmutz, and F. Merkt, textit{Phys. Rev. A}, 89, 043420, 2014.}. They are then excited to high-p Rydberg states by single-photon excitation._x000d_
In the experiments, we use a pulsed uv laser system, with a near Fourier-transform-limited bandwidth of 150 MHz. The Zeeman deceleration reduces the systematic uncertainty arising from a possible Doppler shift and greatly simplifies the spectral assignment because of its spin-rotational state selectivity footnote{P. Jansen, L. Semeria, L. E. Hofer, S. Scheidegger, J. A. Agner, H. Schmutz, and F. Merkt. Phys. Rev. Lett., 115, 133202, 2015.}._x000d_
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Results will be presented on the rotational structure of the lowest three vibrational levels of He. The unprecedented accuracy that we have obtained for the v rotational intervals of He footnote{L. Semeria, P. Jansen and F. Merkt, J. Chem. Phys., 145, 204301, 2016.} enables the quantification of the relativistic and QED corrections by comparison with the results of Tung emph{et al.}$^a
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
FINE STRUCTURE OF METASTABLE 4He2 USING ZEEMAN-DECELERATED MOLECULAR-BEAM RESONANCE SPECTROSCOPY
No full textThe state of He is a metastable state with a lifetime of about \,s.
The spin-spin and spin-rotation interactions result in a splitting of each rotational level into three components . The fine structure intervals of the , , , and - have been measured by radio frequency (rf) spectroscopy\footnote{W. Lichten, M.V. McCusker and T. L. Vierima, \textit{J. Chem. Phys.}, \textbf{61}, 2200 (1974).} \footnote{W. Lichten and T. Wik, \textit{J. Chem. Phys.}, \textbf{69}, 98 (1978).} \footnote{M. Kristensen and N. Bjerre, \textit{J. Chem. Phys.}, \textbf{93}, 983 (1990).} \footnote{I. Hazell, A. N\o rregaard and N. Bjerre, \textit{J. Mol. Spectrosc.}, \textbf{172}, 135 (1995).} and were included in a global analysis of the state \footnote{C. Focsa, P. F. Bernath and R. Colin, \textit{J. Mol. Spectrosc.}, \textbf{191}, 209, (1998).}.
A new measurement of the fine structure of all rotational levels between and of the () state will be presented. The fine-structure components, which are high-field seeking in magnetic fields, have been eliminated using a multistage Zeeman decelerator, and repopulated from the low-field-seeking components using rf radiation prior to detection by excitation to Rydberg states followed by pulsed-field ionization. The low velocity of the Zeeman decelerated beam\footnote{M. Motsch, P. Jansen, J. A. Agner, H. Schmutz and F. Merkt, Phys. Rev. A, \textbf{89}, 043420 (2014).} \footnote{P. Jansen, L. Semeria, L. E. Hofer, S. Scheidegger, J. A. Agner, H. Schmutz and F. Merkt, \textit{Phys. Rev. Lett.}, \textbf{115}, 133202 (2015).} enabled long interaction times of the molecules with the rf radiation and therefore a reduction of the transit-time broadening down to 10 kHz (FWHM), allowing the transition frequencies to be determined very accurately. The fine structure has been analyzed using an effective Hamiltonian to obtain improved values of the spin-spin and spin-rotation coupling constants for the () metastable state of He, including centrifugal distortion corrections
Copium teucrii subsp. iranum W AGNER 1969
No full text<i>Copium teucrii iranum</i> W AGNER, 1969 <p>I R N I r a n: Fars, Shiraz, 3 Ex., 13. V. 1969, leg. Eckerlein H. (3 Paratypes).</p> <p> <b> <i>Copium teucrii teucrii</i> (HOST</b> , <b>1788)</b></p> <p>A U T Ö s t e r r e i c h: Burgenland, Winden E / NSG Hackelsberg, 1 Ex., 24. V. 1967, leg. HA; Burgenland, Oslip SE / Silberberg, 1 Ex., 18. V. 2013, leg. LM; Niederösterreich, Hundsheimer Berg, 7 Ex., 22. VIII. 1960, leg. Weber; Nordtirol, Reutte, 1 Ex., 5. XI. 1914, leg. Knabl; Nordtirol, Zirl Umgebung, 49 Ex., 28. III. 1970, leg. HE; Nordtirol, Innsbruck NW: Planötzen, 1 Ex., 14. X. 1962, leg. HA; Nordtirol, Landeck, 1 Ex., fA, leg. Moosbrugger; Nordtirol, Zirl Umgebung, 14 Ex., 10. V. 1964, leg. HE; Nordtirol, Zirl, 1 Ex., 19. VII. 1962, leg. HA; Nordtirol, Zirl Umgebung, 3 Ex., 23. VI. 1962, leg. PE; Nordtirol, Zirl, 1 Ex., 24. V. 1957, leg. Burmann; Nordtirol, Fliess / Sonnenhänge, 1 Ex., 1. VIII. 1973, leg. HA; Nordtirol, Zirl Umgebung, 2 Ex., 23. V. 1964, leg. HE; Nordtirol, Zams NE / Steinseehüttenweg, 19 Ex., 10. IX. 1987, leg. KM; Nordtirol, Zirl Umgebung, 5 Ex., 12. VIII. 1962, leg. Kapeller R.; Nordtirol, Weissenbach / Feldele, 3 Ex., 22. IX. 1989, leg. KM; Nordtirol, Zirler Weinberg / Zirl NW, 14 Ex., 12. VIII. 1962, leg. HA; Nordtirol, Vomperbach / Schwaz SW, 1 Ex., 1. V. 1964, leg. HE; Nordtirol, Zirler Weinberg / Zirl NW, 5 Ex., 18. VIII. 1962, leg. HA; Nordtirol, Zirler Weinberg / Zirl NW, 2 Ex., 16. VIII. 1962, leg. HA; Nordtirol, Zirler Weinberg / Zirl NW, 2 Ex., 19. VII. 1962, leg. HA; Osttirol, Goggsteig / Lienz S, 2 Ex., 8. VI. 1963, leg. KA.</p> <p>B G R B u l g a r i e n: Warna, Varna (Warna), 3 Ex., 7. VIII. 1957, leg. Eckerlein H.</p> <p>F R A F r a n k r e i c h: Midi-Pyrenees, Albi, 29 Ex., 13. VIII. 1956, leg. Weber; Provence-AlpesCote d'Azur, Mont Ventoux, 1 Ex., 17. VI. 2013, leg. LM; Provence-Alpes-Cote d'Azur, Authon, 2 Ex., 10. VIII. 1956, leg. Eckerlein H.; Provence-Alpes-Cote d'Azur, Tarascon, 1 Ex., 4. VIII. 1955, leg. Eckerlein H.; Provence-Alpes-Côte d'Azur, Digne / Champ de Bes, 1 Ex., 22. VII. 1955, leg. Eckerlein H.</p> <p>G R C G r i e c h e n l a n d: Kreta, Malia, 1 Ex., fA, leg. Franz H.</p> <p>H U N U n g a r n: Wesprim,Vezprem/Liter, 1Ex., 22.V. 2014, leg. MH.</p> <p>I T A I t a l i e n: Brescia, Gargnano, 2 Ex., 1. VIII. 1972, leg. HE.</p> <p>J O R J o r d a n i e n: Amman Governorate, Amman, 1 Ex., 3. VI. 1956, leg. Klapperich J.</p> <p>M A R M a r o k k o: Souss-Massa-Draa,TiznitNE/FlussMassa, 2Ex., 8. V. 1967, leg. Eckerlein H.</p>Published as part of <i>Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1)</i> on pages 98-99, DOI: <a href="http://zenodo.org/record/7507194">10.5281/zenodo.7507194</a>
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Value of photo assessment in late patch-test readings—A multicenter study from six European patch-test clinics
No full textBackground: It is recommended that patch-test readings include a day (D)7 reading. Substitution of the D7 reading with a photo may be a valid option. Objectives: To compare the sensitivity of digital photos at D7 to clinical readings, to assess the number of positive reactions appearing at D7 only (late reactions), and after D7 only (delayed reactions). Methods: Patients patch tested in six European clinics were instructed to forward photos of the patch test reactions to the respective clinics at D7 (before attending the clinic) and at D21. Only allergens in the baseline series or TRUE Test were included in the data analysis. Results: Two hundred ninety-three of 629 patients had a total of 599 positive reactions, with 6.3% occurring at D7 only. When substituting the D7 reading with a photo (90% submitted), 26.3% of late reactions were missed and nine false-positive reactions were found. Delayed reactions were detected in four patients at D21 (65.3% submitted). Conclusion: Our data show that if the D7 reading is not performed, 6.3% of positive reactions from the baseline series would be missed, and if substituting the D7 reading by digital photo, 26.3% late reactions would be missed. Delayed reactions seemed rare
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