2,824 research outputs found
Recording of interview with Wayne Muller
No full textMuller is an author, psychotherapist and minister living in Fairfax, CA. Muller met Nouwen as a student at Harvard Divinity School (Cambridge, MA) from 1982-1985; Muller took Nouwen's Introduction to the Spiritual Life course in the Spring semester of 1983.1 audio cassette (1 hr., 30 mins.)Title based on contents of the item. ; Reference copies of the audio cassettes are available (located with originals). ; Located in audio cassettes box 13. ; No reproduction of this material without permission of the Archivist. ; The interview has been transcribed and is available electronically and in hard copy. ; Digitized February 3, 2011.For more information please contact Special Collections, the University of St. Michael's College.Item consists of one audio cassette (SR2007 66 66 53) of an interview with Wayne Muller conducted by Sue Mosteller, csj on October 31, 2004 at the San Damiano Retreat Centre in Danville, CA. Themes present in Muller's interview include death, grief, Buddhism, fundamentalism and Nouwen's legacy
Design and Optimization of Microwave Lumped Elements Fllters using mixed Circuital-Electromagnetic Simulations
No full textThis paper presents the design, fabrication and experimental results of the switchable band-pass lumped elements filters. The design is based on a new optimization approach that integrates mixed circuital and electromagnetic simulations. The use of horizontal internal ports and the connection of external capacitors at circuital level make the optimization procedure very efficient. A very good agreement between measurements and simulations validate the new design approach
Herbert J. Muller Distinguished Visiting Professor
No full textHerbert J. Muller, American historian, professor, government official, and author, is speaking at The University of Alabama around 1968
Chimpanzees and human evolution/ edited by Martin N. Muller, Richard W. Wrangham, and David R. Pilbeam.
No full textIncludes bibliographical references and index.Although chimpanzees and other primates are frequently used as models to reconstruct the behavior of extinct human ancestors, this is rarely done in a consistent or methodologically rigorous fashion. This volume brings together leading scholars to explore how knowledge about chimpanzees can be used to understand both what is unique about our own species, and how these traits evolved. The first part of the book makes the case that the last common ancestor of chimpanzees and humans was chimpanzee-like. This inference is based not on an assumption that chimpanzees are a model species, but on morphological, developmental, and genetic data, together with evidence from the hominin fossil record. The second part of the book provides the first detailed record of the similarities and differences between humans and chimpanzees, including those in social system, mating system, diet, social behavior, hunting, tool use, culture, cognition, and communication.--Martin N. Muller -- Reconstructing the last common ancestor of chimpanzees and humans / David R. Pilbeam and Daniel E. Lieberman -- Brian Hare and Richard W. Wrangham -- Martin N. Muller -- Michael D. Gurven and Cristina M. Gomes -- Melissa Emery Thompson and Peter T. Ellison -- Herman Pontzer -- Sherry V. Nelson and Marian I. Hamilton -- Rachel N. Carmody -- Brian M. Wood and Ian C. Gilby -- Martin N. Muller and David R. Pilbeam -- Bernard Chapais -- Michael l. Wilson and Luke Glowacki -- Richard W. Wrangham and Joyce Benenson -- Adrian V. Jaeggi, Paul l. Hooper, Ann E. Caldwell Hooper, Michael D. Gurven, Jane B. Lancaster and Hillard S. Kaplan -- Martin N. Muller -- Campbell Rolian and Susana Carvalho -- Joseph Henrich and Claudio Tennie -- Alexandra G. Rosati -- Christopher Boehm -- Katie E. Slocombe and Thom Scott Philips. Was the last common ancestor of chimpanzees and humans chimpanzee-like? -- Introduction: chimpanzees and human evolution / Equal, similar, but different: convergent bonobos and conserved chimpanzees / Chimpanzees and the evolution of human uniqueness -- Introduction: chimpanzees and human uniqueness / Mortality, senescence, and lifespan / Fertility and fecundity / Locomotor ecology and evolution in chimpanzees and humans / Evolution of the human dietary niche: initial transitions / Evolution of the human dietary niche: quest for high quality / From pan to man the hunter: hunting and meat sharing by chimpanzees, humans, and our common ancestor / The evolution of the human mating system / From chimpanzee society to human society: bridging the kinship gap / Violent cousins: chimpanzees, humans, and the roots of war / Cooperative and competitive relationships within sexes / Cooperation between the sexes / Sexual coercion in chimpanzees and humans / Tool use and manufacture in the last common ancestor of pan and homo / Cultural evolution in chimpanzees and humans / Chimpanzee cognition and the roots of the human mind / Ancestral precursors, social control, and social selection in the evolution of morals / Communication and language1 online resource (ix, 837 pages)
The development of a novel native prothrombin assay for the more efficient management of oral anticoagulation therapy
No full textDisturbances of the natural balance between pro-coagulant and anticoagulant systems, due to hereditary or acquired factors may result in haemorrhagic or thrombotic diseases.
Currently the INR/ISI coagulation monitoring system, introduced in 1983 by the World Health Organisation (WHO), is that of choice for most anticoagulation management clinics. Patients undergoing anticoagulation therapy must regularly attend specialised outpatient clinics for the close monitoring and maintenance of their INR. The automated laboratory caters for rapid online simultaneous analysis of multiple blood samples, resulting in the calculation of a patient’s INR from the recorded prothrombin time. The insensitivity of the prothrombin time test has been well documented, requiring a reduction in the prothrombin concentration of 45 % prior to the materialisation of clinically significant prothrombin times.
The project aims to employ three avenues of biotechnology to aid in the development of an immuno or molecular imprinted polymer (MIP) based anticoagulation assay. The project will utilise computational molecular modelling in an attempt to visualise the tertiary structure of human prothrombin, which will allow the rational selection of antigenic sites for molecular imprinting or antibody production.
An aqueous, prothrombin-imprinted homo-polymer was grafted to the gold surface of a surface plasmon resonance biosensor (Biacore). The Biacore allowed the real time monitoring of imprinted polymer binding characteristics to i
homogeneous protein solutions. As a direct comparison of two technologies, molecular imprinting and immuno technology, polyclonal antibodies showing specificity towards the same prothrombin antigen were immobilised onto Biacore chips. The imprinted polymer graft and polyclonal antibody based assays recognised homogeneous solutions of prothrombin at a concentration range of 0.01 nM to 14.2 nM and 0.01 nM to 0.5 nM respectively. A randomised preliminary clinical trial was initiated to compare the two assays’ ability to differentiate plasma samples with a variety of INR values.
The results thus far show promise for the development of a new anticoagulation assay using molecularly imprinted polymer technology. The ultimate aim for this project is to develop a consistently more accurate point-of-care anticoagulation therapy monitoring kit, incorporating this new technology, which can replace or be used concomitantly with the INR/ISI system currently in use. This thesis raises more questions regarding the efficacy of oral anticoagulation therapy (OACT) and argues for and against the necessity of a novel OACT management assay
Author ID’s: enhance visibility and accessibility: Workshop 2
No full textPapers presented at the second workshop on Author ID’s: enhance visibility and accessibility , Auditorium, Merensky Library, University of Pretoria, 28 October 2015Follow up on the first workshop (Researcher ID Workshop), the aim of this workshop was to continue discussion on the information specialists' role in enhancing research visibility and accessibility. A large part of the workshop was devoted to a discussion and practical demonstration of ORCID ID by Mr Matthew Buys, the Regional Director of ORCID. Author IDs were also discussed from different perspectives, including a junior information specialist (Ms Lesego Makhafola); a cataloguer (Ms Martha De Waal); a researcher (Prof. Estelle Venter) and a case study at GIBS (Ms Beulah Muller).mn201
Herbert J. Muller, speaking at The University of Alabama
No full textHerbert J. Muller, American historian, professor, government official, and author, is speaking at The University of Alabama around 1968
Ten year stretch celebrating a decade of crime fiction at CrimeFest
No full textThe twenty brand new crime stories in this book have been specially commissioned to celebrate the tenth anniversary of CrimeFest, described by the Guardian as "one of the 50 best festivals in the world." Contributors come from around the world and include the legendary Maj Sjöwall who, together with partner Per Wahlöö, was the originator of Nordic noir. The editors are Martin Edwards and Adrian Muller. Martin Edwards is responsible for many award-winning anthologies and Adrian Muller is one of the co-founders of CrimeFes
A case study on project-level CO2 mitigation costs in industrialised countries: the Climate Cent Foundation in Switzerland
No full textThis paper analyses CO2 emissions reduction costs based on project data from the Climate Cent Foundation (CCF), a climate policy instrument in Switzerland. Four conclusions are drawn. First, for the projects investigated, the CCF on average pays €63/ton. Due to the Kyoto Protocol, the CCF buys reductions only until 2012. This cut-off increases reported per ton reduction costs, as the additional lifetime project costs are set in relation to reductions only until 2012, rather than to reductions realised over the whole lifetime. Lifetime reduction costs are €45/t. Second, correlation between CCF's payments and lifetime reduction costs per ton is low. Projects with low per ton reduction costs should thus be identified based on lifetime per ton reduction costs. Third, the wide range of project costs per ton observed casts doubts on the widely used identification of the merit order of reduction measures based on average per ton costs for technology types. Finally, the CCF covers only a fraction of additional reduction costs. Decisions to take reduction efforts thus depend on additional, non-observable and/or non-economic motives. Any generalisation of results has to consider that this analysis is based on prospective costs of a sub-sample of projects in Switzerland.abatement cost curve, Climate Cent Foundation, climate policy, emissions reduction, mitigation costs,
In his lacrimis delectabar. Piangere e ridere in Ildegarda di Bingen
No full textL’articolo analizza, attraverso un’indagine lessicale, medica, teologica e simbolica, le forme e i significati del pianto e del riso nell’opera di Ildegarda di Bingen. La monaca benedettina, figura eminente del XII secolo, interpreta queste manifestazioni affettive come espressioni della complessa unità psicofisica dell’essere umano, situata tra caduta e redenzione, natura e grazia. Il pianto, oggetto di una riflessione articolata nei testi visionari, medico-scientifici e morali, assume valenze molteplici: da sintomo fisiologico a segno di compunzione, da strumento ascetico a prefigurazione escatologica. Similmente, il riso è considerato nella sua ambivalenza originaria, capace di esprimere sia la gioia edenica sia la corruzione postlapsaria, fino a trovare nella letizia spirituale una forma ricomposta e trasfigurata. Ildegarda distingue il riso smodato, animale e dannoso, dalla vera iucunditas, frutto della sinergia armonica tra anima e corpo. In tale prospettiva, l’autrice mostra come l’antropologia ildegardiana, fondata su una visione integrale e dinamica dell’essere umano, attribuisca a lacrime e sorriso un valore terapeutico, morale e salvifico, in consonanza con la tradizione monastica e la visione cosmica della creazioneThis article examines the meanings and functions of weeping and laughter in the work of Hildegard of Bingen through a multidisciplinary lens that includes lexical, medical, theological, and symbolic analysis. The twelfth-century Benedictine nun interprets these affective expressions as manifestations of the complex psychosomatic unity of the human being, positioned between fall and redemption, nature and grace. Weeping, addressed across her visionary, medical-scientific, and moral writings, assumes a wide range of meanings: from physiological symptom to sign of compunction, from ascetic tool to eschatological anticipation. Similarly, laughter is explored in its original ambivalence—as capable of expressing both Edenic joy and postlapsarian corruption—before being reconfigured as spiritual iucunditas, the fruit of a harmonious synergy between soul and body.
Hildegard sharply distinguishes between excessive, animalistic, and harmful laughter and the true joy that arises from spiritual integrity. In this framework, the author demonstrates how Hildegard’s anthropology—integral and dynamic—assigns tears and laughter a therapeutic, moral, and salvific function, in continuity with monastic tradition and within the broader cosmic vision of creation
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