81 research outputs found
Biomaterials in gastroenterology: a critical overview
No full textIn spite of the large diversity of diagnostic and interventional devices associated with gastrointestinal endoscopic procedures, there is little information on the impact of the biomaterials (metals, polymers) contained in these devices upon body tissues and, indirectly, upon the treatment outcomes. Other biomaterials for gastroenterology, such as adhesives and certain hemostatic agents, have been investigated to a greater extent, but the information is fragmentary. Much of this situation is due to the paucity of details disclosed by the manufacturers of the devices. Moreover, for most of the applications in the gastrointestinal (GI) tract, there are no studies available on the biocompatibility of the device materials when in intimate contact with mucosae and other components of the GI tract. We have summarized the current situation with a focus on aspects of biomaterials and biocompatibility related to the device materials and other agents, with an emphasis on the GI endoscopic procedures. Procedures and devices used for the control of bleeding, for polypectomy, in bariatrics, and for stenting are discussed, particularly dwelling upon the biomaterial-related features of each application. There are indications that research is progressing steadily in this field, and the establishment of the subdiscipline of “gastroenterologic biomaterials” is not merely a remote projection. Upon the completion of this article, the gastroenterologist should be able to understand the nature of biomaterials and to achieve a suitable and beneficial perception of their significance in gastroenterology. Likewise, the biomaterialist should become aware of the specific tasks that the biomaterials must fulfil when placed within the GI tract, and regard such applications as both a challenge and an incentive for progressing the research in this field
Bioequivalence study of three ibuprofen formulations after single dose administration in healthy volunteers
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Clinical Features, Endoscopic Management and Outcome of Patients with Non-variceal Upper Digestive Bleeding by Dieulafoy Lesion
No full textQUAND L HOMME DEVIENT BÊTE : L'ANIMAL AU SERVICE D'UNE IDEOLOGIE DANS MAQUIS DE CERVERA
No full textInternational audienceIn 1997, the Spanish author Alfons Cervera publishes Maquis to give the floor to those that the History forgot, those who continued the fight against Franco while the Civil War was officially ended. The author offers a poignant, often crude and rough story on the fratricide fight which goes on between both sides. The confrontation quickly raises the question of the place of the humanity while the animality progresses as the war of resistance gets stuck. Analyzing the various ways of loss of humanity organized around three axes that are the animality, the madness and the bestiality, we want to show how the subtle demarcation between bestiality and animality allows to question the apparent ecuminicism of a novel where each part would assume its part of inhumanity.En 1997, l'auteur espagnol Alfons Cervera publie Maquis afin de rendre la parole aux oubliés de l'histoire, ceux qui ont continué la lutte contre Franco alors que la Guerre était officiellement terminée. L'auteur offre un récit poignant, souvent cru et brutal sur la lutte fratricide qui se prolonge entre les deux camps. L' affrontement pose très vite la question de la place de l'homme dont l'animalisation progresse à mesure que la guerre de résistance s'enlise. Analysant les différents processus de perte d'humanité organisés autour de trois axes que sont l'animalisation, la folie et la bestialité, nous montrons comment la subtile délimitation entre animalité et bestialité permet de remettre en question une oeuvre à l'oecuménisme avoué où chaque clan assumerait sa part d'inhumanité
Depressive disorder influence on the quality of life of the patient with degenerative pathology
No full textIn chronic rheumatic diseases, we frequently follow the physical dimension of the disease and less the mental and social dimension of it. In the recent years, there has been a great interest in measuring the quality of life reflecting together all these three dimensions. The aim of this study was to assess and compare the perception of pain, quality of life of the patients with depression respectively without depression, using assessment tests recognized and accredited in Romania. We conducted an observational study on a group of 20 patients (n=20). The subjects were randomized of the patients hospitalized at ,,Avram Iancu’’ Clinical Hospital, Oradea, over a period of 2 weeks(in January-February 2016).All the cases were staged according to current criteria approved in Romania. Data collection was prospective and was made directly by examining the patients. Assessment methods are standardized in order to limit as much as possible the influence of systematic error. Initial evaluation and monitoring the patients consisted of physical examination, muscular and articular consultations, assessment of the pain, and depression and quality. We observe higher incidence of depression among women, 70% in the studied group. We assessed the pain expressed by the patients objectively on the VAS pain scale. The mean values of pain were as follows: group I- initially3.8, at the end of treatment1.4; the second group - initially 6.2 and finally 4. The initial average values of the pain were lower in the group without depression and also the treatment response and mean values in group I were significantly superior to of the second group. From the analysis of the data obtained we observe that the average quality of life of the patients from group I is 1.81 and increases after treatment with a percentage of 41.4%.The average value of HAQ score in the group of patients with depressive disorder is 2.03, decreasing to 1.37 after treatment. That means an improvement of 32.17%. The number of women that addresses for recovery treatment is higher. We observe a higher incidence of depression among women, 70% in the study group. The average value of the pain of the patients from group I is lower both initially and at the end of the study than the average pain of the patients from group II, result otherwise expected because the perception of pain is higher at patients with depression and treatment response it is more modest. In the case of first group, the mean value of the pain decreases by 63.15%, while for the second group the decrease is 30.64%. From the analysis of the obtained data we observe that the average quality of life of the patients from group I is 1.81 and increased after treatment with a percentage of 41.4%. The average value of the HAQ score in the group of patients with depressive disorder is 2.03, this dropped to 1.37 after treatment. That means an improvement of 32.17%.
KEYWORDS: chronic rheumatic diseases, quality of life, depressive disorder
THEORIES CONCERNING THE ASSURENCE OF DIVERSITY IN TEACHING ATHLETIC EXERCISES: TEORII PRIVIND ASIGURAREA VARIETĂÅ¢II ÂN PREDAREA EXERCIÅ¢IILOR DE ATLETISM
No full textThis work tries to mention a few of action goals to assure diversity in the athletic exercises teaching process. Starting from some fundamental teaching principles the author shows a few types of exercises wich can be used properly in teaching athletic exercises. Also we can find old and new ideas of competitions. Some interesting ideas regarding pedagogical perspectives are shown. A large part of the work is treating games to assure diversity in teaching athletics. Some ideas regarding the indoor athletic activity are completing this work.
Rezumat
Lucrarea de față încercă să menționeze câteva obiective de realizat pentru asigurarea varietății în predarea exercițiilor de atletism. Pornind de la câteva principii fundamentale de predare autorul prezintă câteva exerciții care pot fi utilizate la modul optimal în predarea exercițiilor de atletism. De asemenea se regăsesc idei vechi și noi cu privire la întrecerile atletice. Se menționează câteva idei interesante cu privire la perspectivele pedagogice cu referire la predare exercițiilor de atletism. O amplă parte a lucrării se referă la jocurile de motricitate menite să asigure varietatea în predarea exercițiilor de atletism. Câteva idei privind activitatea atletică în interior sunt menite a completa prezenta lucrare
Jeux de la métamorphose dans deux textes du Cinquecento florentin : L'Âne d'or de Machiavel et La Circé de Gelli
No full textInternational audienceAbstract – Machiavelli's unfinished poem, " The Golden Ass " , undertaken about 1517, was published in 1549, the same year as Giovan Battista Gelli's " Circe ". Drawing its inspiration from Apuleius' celebrated " Golden Ass " and Dante's " Divine Comedy " , this text, by which Machiavelli intends to stand as the judge of his time, ends with the rewriting of one of Plutarch's famous " moral works " devoted to the superiority of animal condition. Gelli takes up the latter notion illustrating it through a fully distinct work, in the form of a series of dialogues uttered on the island of Circe: Ulysses proposes to the animals to give them back their original human form but they obstinately refuse his offer. Machiavelli's poem was indeed a vengeful political fable – Gelli's " Circe " , as far as it is concerned, appears to be as a philosophical and humanistic lesson addressed by the author to his contemporaries.– Le poème inachevé de Machiavel, « L'Âne d'or », entrepris vers 1517, fut publié en 1549, la même année que « La Circé » de Giovan Battista Gelli. Inspiré du célèbre « Âne d'or » d'Apulée et de la « Divine Comédie » de Dante, ce texte, par lequel Machiavel entend se faire justicier de son époque, se termine sur la réécriture d'une célèbre « oeuvre morale » de Plutarque qui est un éloge de la supériorité de la condition animale. Gelli reprend cette dernière idée et lui consacre une oeuvre à part entière, sous la forme d'une série de dialogues advenus sur l'île de Circé où les animaux à qui Ulysse propose de rendre leur forme humaine, refusent l'offre énergiquement. Tandis que le poème de Machiavel était une fable politique vengeresse, « La Circé » de Gelli apparaît comme une leçon de philosophie et d'humanisme adressée par l'auteur à ses contemporains
INFLUENŢA LUI VERNE ÎN ATLANTIDE (1901) DE YAMBO
No full textInternational audienceThis article examines the intertextual connexions between Yambo's Atlantide (1901) and Verne's novels Voyage au centre de la terre (1864) and Vingt mille lieues sous les mers (1869). It aims to point out not only Verne's presence in Yambo's novel, but also the way in which the Italian author appropriates motifs borrowed from the French model. This personal appropriation shows how very different the ideology and the pedagogical project underlying the two novelists' writing are. Thus, even if youth and mass literature is usually strictly codified and relies on the pleasure the reader gets from recognizing recurring stereotypes, we will show how Yambo innovated due to his personal project or the different historical and cultural context. Résumé Cet article est consacré à l'étude de l'intertextualité reliant Atlantide (1901), de Yambo, aux romans verniens Voyage au centre de la terre (1864) et Vingt mille lieues sous les mers (1869).Il s'applique à relever non seulement les occurrences verniennes chez Yambo, mais également la manière dont l'auteur italien s'est emparé de motifs empruntés à son modèle. Cette appropriation personnelle révèle une différence significative de l'idéologie et du projet pédagogique sous-jacents à l'écriture des deux romanciers. L'analyse permet ainsi de souligner la marge de créativité dont l'auteur toscan a fait preuve, en raison de ses préoccupations propres ou du contexte culturel et historique différent, dans le cadre d'un type d'écriture (la littérature populaire et de jeunesse) normalement soumise à de contraintes lourdes et fondée sur le plaisir qui découle de la reconnaissance de stéréotypes récurrents.Rezumat Acest articol examinează conexiunile intertextuale între Atlantida lui Yambo (1901) şi romanele lui Verne Călătorie spre centrul pământului (1864) şi Douăzeci de mii de leghe sub mări (1869). Ţinteşte să arate nu doar prezenţa lui Verne în romanul lui Yambo, dar de asemenea felul în care autorul italian potriveşte motivele împrumutate din modelul francez. Această potrivire personală arată modul concret în care sunt diferite ideologia şi proiectul pedagogic care sunt prezente în scrierile celor doi romancieri. Cu toate că, literatura tânără şi în masa este de obicei codificată şi se bazează pe plăcerea pe care scriitorul o experimentează recunoscând stereotipuri, vom arăta cum Yambo a adus o inovaţie prin proiectul lui personal sau diferitul context istoric şi cultural
NECESSITARIANISM IN LEIBNIZ’S CONFESSIO PHILOSOPHI
No full textLeibniz’s Confessio philosophi (1672–1673) appears to provide an anti-necessitarian solution to the problem of the author of sin. I will give here a brief reading of what appear to be two solutions to the problem of the author of sin in the Confessio. The first solution appears to commit Leibniz’s spokesman (the Philosopher) to necessitarianism. The Theologian (Leibniz’s interlocutor) objects to this necessitarianism, prompting the Philosopher to offer a modified version that appears to exorcise this doctrine. As it turns out, Leibniz holds that these two solutions are in fact the same. I will thus conclude by reconciling these solutions, arguing for giving priority to the more radical first solution. I will argue for this by looking at the connections between the Confessio philosophi and some of Leibniz’s other works in its genre around its time. It will be argued that Leibniz does not find the necessitarianism, which references to per se contingencies are supposed to solve, to be problematic in 1673
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