1,720,968 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
EFEK KONSUMSI KEFIR TERHADAP DISLIPIDEMIA TERKAIT SINDROM METABOLIK: SEBUAH TINJAUAN PUSTAKA
No full textLatar belakang: Peningkatan insidensi sindrom metabolik sering disertai dengan dislipidemia. Kefir merupakan minuman fermentasi yang telah banyak diteliti manfaat kesehatannya.Tujuan: Tujuan dari tinjauan ini adalah untuk membahas pengrauh minuman kefir terhadap dislipidemiaMetode: Pencarian literatur dilakuakn dengan menggunakan kata kunci “kefir”, “dislipidemia”, dan “sindrom metabolik” dengan mesin pencari PubMed dan Google Scholar.Hasil: Dislipidemia dapat dipengaruhi dari obesitas dan resistensi insulin. Kefir memiliki efek anti-obesitas dan antiinflamasi dengan memodulasi perbaikan metabolisme lipid.Kesimpulan: Konsumsi kefir memiliki efek antidislipidemia pada sindrom metaboli
Capsaicin 8% Patch Untuk Terapi Alternatif Pada Nyeri Neuropati Diabetikum Perifer
No full textAbstract
Diabetes is one of the most common health problems due to its high incidence and complications. One of the complications associated with diabetes is painful diabetic peripheral neuropathy (PDPN). The capsaicin 8% patch is a localized pain treatment that provides effective pain relief from a single application in patients with peripheral neuropathic pain. The aim of this review is to discuss the effect of capsaicin patch 8% in patients with painful diabetic peripheral neuropathy. The search strategy was conducted in PubMed and modified for other databases. The search was limited to English-language reports. The keywords used were "capsaicinâ€, "capsaicin patch", "painful diabetic peripheral neuropathy", and "pain management". The inclusion criteria used were randomized controlled trials (RCTs), clinical trials or another interventional analysis with full text in English with publications less than the last 10 years. The exclusion criteria used were a review, systematic review, or meta-analysis, studies that were not conducted in humans and non-full text in English with publications over the last 10 years. Results: There are 2 full-text that meet inclusion criteria. From articles related to studies that have been conducted, the use of capsaicin 8% patch can reduce pain, improve nerve function and quality of life in PDPN patients. The use of capsaicin 8% patch has the advantage to pain relief for patients with painful diabetic peripheral neuropathy.
Keywords: Alternative therapy, Capsaicin 8% Patch, Diabetes complications, Pain Relief, Painful Diabetic Peripheral Neuropathy, topical drugsAbstrak
[Capsaicin 8% Patch untuk Terapi Alternatif Neuropati Perifer Diabetik yang Menyakitkan]
Diabetes merupakan salah satu permasalahan kesehatan karena insidensi yang tinggi dan komplikasinya. Salah satu komplikasi terkait diabetes adalah nyeri neuropati diabetikum perifer/painful diabetic peripheral neuropathy (PDPN). Capsaicin 8% patch merupakan pengobatan nyeri yang terlokalisir yang menyediakan pereda nyeri pada pasien dengan nyeri neuropati perifer. Tujuan dari tinjauan ini adalah untuk membahas efek capsaicin patch 8% pada pasien dengan nyeri neuropati perifer diabetikum. Pencarian literatur dilakukan dengan menggunakan mesin pencari PubMed dan sumber data terkait lainnya. Pencarian terbatas pada studi berbahasa Inggris. Kata kunci yang digunakan antara lain "capsaicinâ€, "capsaicin patch", "painful diabetic peripheral neuropathy", dan "pain management". Kriteria inklusi yang digunakan antara lain studi berupa randomized controlled trials (RCTs), clinical trials atau studi intervensi lainnya dengan full text berbahasa Inggris dengan publikasi kurang dari 10 tahun. Kriteria eksklusi yang digunakan adalah studi berupa tinjauan, tinjauan sistematis, atau meta-analisis, studi tidak dilakukan pada manusia, bukan full text berbahasa Inggris dengan riwayat publikasi lebih dari 10 tahun. Terdapat dua studi yang memenuhi kriteria inklusi. Dari artikel studi yang telah dilakukan, penggunaan capsaicin 8% patch dapat menurunkan nyeri, memperbaiki fungsi saraf dan kualitas hidup pasien dengan nyeri neuropati perifer diabetikum. Penggunaan capsaicin 8% patch memiliki keuntungan pereda nyeri untuk pasien nyeri neuropati perifer diabetikum.
Kata kunci: capsaicin 8% patch, komplikasi diabetes, nyeri neuropati perifer diabetikum, obat topikal, pereda nyeri, terapi alternati
The effect of probiotic supplementation as alternative therapy for NAFLD: a literature review
Full text linkBackground: Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases, influenced by various risk factors associated with metabolic disorders. Currently there is no specific effective treatment for NAFLD. Probiotics have been extensively researched for their health benefit Probiotic Supplementation for NAFLD. Methods: A simple literature review was performed based on searches via PubMed, ScienceDirect and Google Scholar, using the keywords "probiotic," "microbiota," "non-alcoholic fatty liver disease," "metabolic disorder," and "therapy." Results: Research on the use of probiotics for NAFLD demonstrated improvement in liver function and histology. However, the literature is inconsistent regarding the probiotics’ influence on the NAFLD risk factors. Probiotics can be an alternative therapy for NAFLD through the ability to modulate the microbiota of the gastrointestinal tract. Conclusion: Probiotics can be an alternative therapy in NAFLD patients, however more extensive studies are needed to ensure the safety of this approach
IL-17/TNF-? BISPECIFIC ANTIBODIES AS NEW THERAPEUTIC APPROACH TO RHEUMATOID ARTHRITIS
No full textRheumatoid arthritis is a systemic autoimmune disease characterized by chronic inflammation causing swelling in the joints. IL17/TNF-? bispecific antibodies are antibodies that can bind to two different types of epitopes and work on two different types ofreceptors. IL-17/TNF-? bispecific antibodies have anti-inflammatory effects that act by blocking the inflammatory pathways ofrheumatoid arthritis. Thus, bispecific antibodies have the potential to be the latest effective therapy against rheumatoid arthritis.Keywords: Bispecific antibodies, rheumatoid arthritis, therapeutic
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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