199 research outputs found
EFFECT OF INTERNET ADDICTION AMONG STUDENTS OF MATHEMATICS IN ADEYEMI FEDERAL UNIVERSITY OF EDUCATION, ONDO
Get PDFThis study investigated the effect of internet addictions among students of mathematics in Adeyemi College of Education, Ondo. Descriptive survey research questions were raised to guide the study. Data were collected by the researcher using questionnaire and analysed using descriptive statistics. The findings revealed that internet significantly influence student learning experiences. Also, the addiction of mathematics students on social media negatively influences their academic performance. Gender significantly influences internet addiction among undergraduate students. It was recommended that counselors should assist in counseling mathematics students on the danger of internet addiction on their academic performance. Mathematics students should desist from internet activities such as gambling, watching pornographic videos as it can distract them from their academic pursuit
sj-pdf-1-whe-10.1177_17455065211060637 – Supplemental material for Eight-hour versus 24-h urethral catheter removal following elective caesarean section for reducing significant bacteriuria: A randomized controlled trial
No full textSupplemental material, sj-pdf-1-whe-10.1177_17455065211060637 for Eight-hour versus 24-h urethral catheter removal following elective caesarean section for reducing significant bacteriuria: A randomized controlled trial by Emeka Philip Igbodike, Ibraheem Olayemi Awowole, Olufemi O Kuti, Kayode Olusegun Ajenifuja, George Uchenna Eleje, Simeon Olugbade Olateju, Bolatito Opeyemi Olopade, Omotade Adebimpe Ijarotimi, Emmanuel Oladayo Irek, Njideka Theresa Igbodike, Oluwole Ekundayo Ayegbusi, Joseph Ifeanyichukwu Ikechebelu, Boniface Chukwuneme Okpala, Olabisi Morebisi Loto, Akintunde Olusegun Fehintola, Akinyosoye Deji Ajiboye, Olusola Fajobi, Chima Stephene Abuchi, Uchenna Uchenna Onwudiegwu, Olusola Benjamin Fasubaa, Ernest Okechukwu Orji, Olufemiwa Niyi Makinde, Alexander Tuesday Owolabi and Adebanjo Babalola Adeyemi in Women’s Health</p
sj-sav-1-whe-10.1177_17455065211060637 – Supplemental material for Eight-hour versus 24-h urethral catheter removal following elective caesarean section for reducing significant bacteriuria: A randomized controlled trial
No full textsj-sav-1-whe-10.1177_17455065211060637 for Eight-hour versus 24-h urethral catheter removal following elective caesarean section for reducing significant bacteriuria: A randomized controlled trial by Emeka Philip Igbodike, Ibraheem Olayemi Awowole, Olufemi O Kuti, Kayode Olusegun Ajenifuja, George Uchenna Eleje, Simeon Olugbade Olateju, Bolatito Opeyemi Olopade, Omotade Adebimpe Ijarotimi, Emmanuel Oladayo Irek, Njideka Theresa Igbodike, Oluwole Ekundayo Ayegbusi, Joseph Ifeanyichukwu Ikechebelu, Boniface Chukwuneme Okpala, Olabisi Morebisi Loto, Akintunde Olusegun Fehintola, Akinyosoye Deji Ajiboye, Olusola Fajobi, Chima Stephene Abuchi, Uchenna Uchenna Onwudiegwu, Olusola Benjamin Fasubaa, Ernest Okechukwu Orji, Olufemiwa Niyi Makinde, Alexander Tuesday Owolabi and Adebanjo Babalola Adeyemi in Women’s Health</p
Characterization of Legionella pneumophila Effector Proteins, LneB and MavA
Get PDFThe crucial virulence factor of accidental human pathogen Legionella pneumophila during the course of Legionnaire disease is the over 300 effector proteins secreted from its Dot/Icm secretion system. Eukaryotic host cells usually elicit an arsenal of immune responses against invading L. pneumophila. Nonetheless, the bacteria unexpectedly subvert these defense mechanisms to survive and proliferate unhindered in the host. Although some effector proteins have been proposed to play a significant role in this host-pathogen interaction, many still need to be characterized. The LneB and MavA proteins are examples of those effectors that need characterization. Thus, this study aimed to investigate the structural and functional characteristics of LneB and MavA proteins using several bioinformatics predictive pipelines and transcriptomics data supplemented experimentally through cell-based and biochemical assays to support the prediction.
The LneB protein was predicted to have histone acetylation activity (HAT) based on bioinformatics analysis. To investigate the HAT activity of LneB in vitro, the protein was ectopically expressed in the Escherichia coli BL21 strain and purified using nickel ion chromatography. The HAT activity assay was carried out on the purified LneB protein and on the nuclear extracts from LneB-GFP transfected 293T cells. Transcriptomics analysis shows that the LneB protein differentially induces upregulation of early growth factor and dehydrogenase (DHRS2) compared to the GFP control.
There was no significant difference between the in vitro HAT activity of LneB protein and the elution buffer (p-value = 0.1137, t-value = 5.537). In vivo, HAT activity was significantly reduced in cells transfected with LneB protein compared to the GFP control (p-value = 0.0025, t-value = 20.08). The HAT activity is not significantly different at a MOI of 10 or 100 when infected cells (Dot/Icm mutant and wild-type L. pneumophila) are compared to uninfected U937 cells (p-value = 0.8969 and 0.5384, respectively). However, the HAT activity in cells infected with an L. pneumophila Dot/Icm mutant at MOI of 100 was significantly lower than in cells that were not infected (p-value = 0.0236). This result suggests that the effector protein from the wild type plays a significant role in acetylating histone protein in the host. Further investigation is required to understand the HAT activity of LneB and other roles the protein could play in the host.
Our bioinformatics analysis suggested that the MavA protein possesses Ras-GEF domains and potentially binds to GTP. The protein is predicted to possess two coiled-coil domains and also interact with GTP, Ras and actin. The transcriptomic data from cells expressing MavA protein showed significant upregulation of sixteen genes, which are involve in steroid hormone metabolic processes, endocytic recycling, cilia movement among others. The sortilin receptor protein was the only repressed gene in the cell when compared to a GFP protein control. Connecting the bioinformatics finding and the review of literature, we suggested that the MavA protein could be involved in the biological process in the cell such as internalization of L. pneumophila, creation of Legionella-containing vacuoles in host cells through endosomal remodeling or cytoskeletal reorganization
Solid Verifiable Credentials
No full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2019Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 63-66).Credentials are an integral part of our lives, as they express our capabilities and enable access to restricted services and benefits. In the early 2010s, the Verifiable Claims Working Group of the World Wide Web Consortium (W3C) proposed a specification for what is now the Verifiable Credentials Data Model. This living specification, which is still in development, outlines a cogent framework for the issuance, storage, presentation, and verification of credentials on the Web. Many of the leading Verifiable Credentials projects leverage Distributed Ledger Technology (DLT), potentially compromising Web interoperability and sometimes exposing otherwise personal data. SolidVC is a decentralized Verifiable Credentials platform built with the open protocols of the Web. It is implemented on top of Solid, a Web framework developed at MIT in 2016 that allows decentralized applications to interact with personal user data to provide services in an access controlled environment.by Kayode Yadilichi Ezike.M. Eng.M.Eng. Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Scienc
<b>The Future of Cryptocurrency in the Nigerian Financial Services System: A 2024 Perspective</b>
No full textThe narrative surrounding cryptocurrency in Nigeria is undergoing a significant transformation, reflecting a broader global shift towards the acceptance and integration of digital currencies within financial systems. The Central Bank of Nigeria (CBN) has evolved from a cautious stance to a more embracing approach, highlighted by the introduction of the eNaira, Nigeria's digital currency, aimed at modernizing the financial ecosystem, enhancing financial inclusivity, and stabilizing the economy. Despite initial regulatory challenges concerning security and compliance, the CBN's progressive policies, including the encouragement of cryptocurrency literacy and the development of supportive frameworks for crypto transactions, signal a future where digital currencies play a crucial role in Nigeria's economic landscape. This shift towards digital currency adoption, underscored by the eNaira's success and the call for continuous collaboration among stakeholders, represents an optimistic outlook for the integration of innovative financial technologies to address longstanding economic challenges and leverage opportunities for growth and stability.</p
Impact of Human Resources Management Practices on Seaport Competitiveness: A Case of Nigerian Seaports
No full textDespite numerous efforts at modernising Nigeria's seaports, they remain inefficient. Many studies have been conducted to find the root cause of the inefficiency and many solutions have been recommended based on findings. The findings have variously pointed to infrastructural decay, inadequacy, and lack of modern seaport technologies as root causes of inefficiency at the seaports. Surprisingly, however, the proffered solutions have all failed to solve the lingering inefficiency and poor performance of the seaports. This suggests that, apart from the challenges associated with poor infrastructure, efforts must be directed at other areas to identify and explain the persistent inefficiencies that have defied many solutions at the seaports. This study, therefore, focusses on identification of the key underlying issues by examining whether there is a relationship between seaport inefficiency and human resources management (HRM) practices of the seaports. Case study approach was adopted, and qualitative data was collected, using semi-structured interview protocol. A qualitative content analysis (QCA) was conducted along with an NVivo program analysis. A total of 34 respondents were interviewed from four categories of key seaport stakeholders comprising of 33 male and one (1) female. Among the respondents are 19 seaport managers (SM), three (3) seaport union executives (SUE), four (4) Customs Area Controllers (CAC) and eight (8) shippers/freight forwarders (SFF). Findings reveal that HRM practices of the seaports are not fully aligned with the business objectives of the Nigerian Port Authority (NPA) mainly due to unfair recruitment and unfair promotion practices. The findings also indicate that the working condition of staff is average and, consequently, staff morale, loyalty, commitment, and productivity are also average. Technologically, findings show the level of technological implementation at the seaports is at best average, as only basic technologies are available for seaport operations. On Corporate Governance (CG), the study finds the appointment of the Board of Directors of the seaport is mainly political. The Board is, therefore, not fully independent because of external political influences. On the overall cost of clearance at the seaports, findings indicate that the official seaport charges at the seaports are reasonable and competitive, but illegal charges extorted from customers make overall clearance cost uncompetitive. Similarly, while the speed of clearing cargo has improved over the years, the level of customer service provided is average. Overall, the findings indicate that modern infrastructure/technology in themselves will not yield any major positive impact in terms of improve competitiveness for the Nigerian seaports without commensurate high-quality governance and human resources (HR) practices identified and addressed in this study.</p
Impact Analysis of Renewable Energy based Generation in West Africa – A case study of Nigeria
Get PDFThe limited supply of fossil fuels, constant rise in the demand of energy and the importance of reducing greenhouse emissions has brought about the adoption of renewable energy sources for generation of electrical power. In this paper, the impact of renewable energy generation in Nigeria is explored. A review of renewable deposits in Nigeria with a focus on Solar, Biomass, Hydropower, Pumped Storage Hydro and Ocean energy is detailed. The impact of renewable energy-based generation is assessed from three different dimensions: Economic Impact, Social Impact and Environmental Impact. In accessing economic impact; the conditions are employment and job creation, gross domestic product (GDP) growth and increase in local research and development. To analyze the social impact; renewable energy education, renewable energy businesses, ministries and institutes, renewable energy projects and investments as well as specific solar and wind projects across Nigeria were considered. Also, environmental issues were discussed. Similarly, policy imperatives for renewable energy generation in Nigeria was provided. This paper would be useful in accessing the successes Nigeria has experienced so far in the area of sustainable development and the next steps to achieving universal energy for all in Nigeria in 2030.Ograniczona podaż paliw kopalnych, stały wzrost zapotrzebowania na energię oraz konieczność ograniczenia emisji gazów cieplarnianych pociągnęły za sobą konieczność stosowania odnawialnych źródeł energii do wytwarzania energii elektrycznej. W artykule zbadano wpływ wytwarzania energii odnawialnej w Nigerii. Szczegółowy przegląd zasobów energii odnawialnej w Nigerii, ze szczególnym uwzględnieniem energii słonecznej, biomasy, energii wodnej i elektrowni szczytowo-pompowych i energii oceanicznej. Produkcja energii ze źródeł odnawialnych została przeanalizowana w trzech różnych wymiarach: wpływ na gospodarkę, wpływ na społeczeństwo i wpływ na środowisko. W aspekcie wpływu na gospodarkę wzięto pod uwagę: zatrudnienie i tworzenie miejsc pracy, wzrost produktu krajowego brutto (PKB) oraz wzrost lokalnych badań i rozwój. Analiza wpływu społecznego objęła: edukację w zakresie energii odnawialnej, przedsiębiorstwa, ministerstwa i instytuty zajmujące się energią odnawialną, projekty i inwestycje w zakresie energii odnawialnej, a także konkretne projekty dotyczące energii słonecznej i wiatrowej w całej Nigerii. Omówiono również kwestie środowiskowe. W podobny sposób przedstawiono imperatywy polityczne dotyczące wytwarzania energii odnawialnej w Nigerii. Ten artykuł wskazuje na istotny dla Nigerii cel zrównoważonego rozwoju, jakim jest odnawialna energia dla wszystkich. Celem jest osiągnięcie w tym kraju powszechnej odnawialnej energii dla wszystkich w 2030 r
Household energy conservation behaviour: A socio-economic perspective
Get PDFStudies on energy conservation and household behaviour were predominantly based on econometrics using secondary data with limited studies employing the primary data. In addition, the use of secondary data from developing countries are not without their inadequacies due to missing data points. However, generating data may lead to over or under estimations which led to this study deploying structural equation model and making use of cross-sectional data from a developing country perspective. Data were collected through a structured questionnaire from 329 respondents in Akure Metropolis households, Nigeria, that were selected using a random sampling techniques. The study adopted the Partial Least Square Structural Equation Modelling approach. The results of the study showed that socio-economic variables electricity price, household size, income, number of appliance and weather have significant effects on energy conservation behavior with income having the largest structural weight. This implies that income is of utmost importance to residents` electricity saving practices as householders consume more and save less electricity with more income. It is therefore recommended that energy conservation policy should aim at regulating the purchase of electricity units at household levels, where the rich pay more tax than the poor. This will foster energy saving improvement at households sector of the Nigerian economy
Comparative Analysis of Postgraduate Students' Thesis Supervision and Mentoring in Oyo State, Nigeria
No full textA close look at situations in universities in Nigeria suggests that the majority of postgraduate students do not complete their programmes by the deadline, despite having completed coursework requirements for the programmes. Some even abandon their thesis and go on leave for reasons best known to them. This study did a comparative analysis of postgraduate students’ thesis supervision and mentoring in universities in Oyo State. The descriptive survey research design was adopted; the population included all postgraduate students in both public and private universities in Oyo State. A self developed instrument tagged ‘Postgraduate Thesis Supervision Questionnaire’ (PTSMQ) was used to source data for the study. According to the findings, there is a significant interaction between the university supervisors and supervisee and also a high level of mentoring. In a similar vein, the results showed that the supervision of postgraduate students theses in university, in Oyo state varied significantly according to the type of university (Private universities with mean = 2.73, SD = 0.856, P < 0.05) and public universities postgraduate students thesis supervision at (mean = 3.07, SD =1.196, P < 0.05). The study equally found a significant university type difference in mentoring of postgraduate student (private university mentoring with mean = 2. 83, SD = 0. 938, P < 0.05 and public university at mean = 3.15, SD = 1.203, P < 0.05). It was concluded that there was a significant difference in thesis supervision and mentoring among postgraduate students in universities in Oyo State. The study recommended among others, that efforts should be made by the government and university administrators to minimize the academic and administrative workload of postgraduate students' thesis supervisors to ensure they dedicate more time to thesis supervision and mentoring
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