1,721,142 research outputs found
Preface: The Irago Conference 2017: A 360-degree Outlook on Critical Scientific and Technological Challenges for a Sustainable Society
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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Abstract 3101: Hyperthermia at the single-cell level for disseminated cancer disease with immuno-magnetic nanoparticles
No full textAbstract
Hyperthermia using magnetic nanoparticles and alternating magnetic field is promising for cancer therapy. In most cases, the usefulness of this magnetic nanoparticle-based hyperthermia has been shown by applying magnetic nanoparticles to tumor tissue such as a subcutaneous tumor with direct injection technique; however, if the magnetic nanoparticles can be cancer cell-specifically delivered at the cellular level, the magnetic field hyperthermia would have the potential to treat various sorts of disseminated cancer diseases. The aim of this study is to prove this concept. Maghemite nanoparticles (MNPs) were conjugated with the anti-HER2 antibody (Tmab) for cancer targeting, and the Tmab-MNPs were applied to the co-culture flask containing both HER2-expressing breast cancer AU565 cells and normal fibroblast FEF3 cells. Thirty minutes later from the Tmab-MNPs administration, the medium was removed and the cells were washed to remove excess Tmab-MNPs. Prussian blue iron staining and immunostaining for Tmab showed co-localization of the maghemite nanoparticles and Tmab only on the cancer cells, which suggested that MNPs conjugation with Tmab was successful and that cancer specific delivery of MNPs at the cellular level was achieved in vitro. Moreover, application of alternating current magnetic field at 280 kHz for 1 hour caused apoptotic-like cell death only to cancer cells without any cell damage to normal fibroblast FEF3 cells. Intracellular hyperthermia using cancer-specific antibody-modified magnetic nanoparticles have the potential to be applied to the treatment of disseminated cancer diseases.
Citation Format: Tetsuya Kagawa, Hiroyuki Kishimoto, Toshiaki Ohara, Hiroshi Tazawa, Shunsuke Kagawa, Takeshi Nagasaka, Satoshi Nohara, Ichiro Kato, Adarsh Sandhu, Hiromichi Aono, Toshiyoshi Fujiwara. Hyperthermia at the single-cell level for disseminated cancer disease with immuno-magnetic nanoparticles [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3101. doi:10.1158/1538-7445.AM2017-3101</jats:p
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