984 research outputs found
Letter from G. Mercer Adams to Olaf Ellison, 1899 Jan 13.
No full textAkron, Ohio, Jan. 13, 1899.Mr. Olaf Ellison,101 Adams Express Bldg.,Chicago, Il1.My dear sir:-I have your favor of yesterday in regard to the article on John Muir which you kindly submitted for SELF CULTURE.I have it entered to appear in the March number of the magazine, and already have the manuscript prepared for press, and a half-tone made of the Muir portrait to embellish the article.I hope you will enjoy your visit to the Pacific Coast on the mission on which you are about to set out. Pray make my compliments to Mr. Muir when you meet.Very sincerely yours,G. Mercer Adams, Editor.02529https://scholarlycommons.pacific.edu/jmcl/27363/thumbnail.jp
Obstructive sleep apnea and schizophrenia: a systematic review to inform clinical practice
No full textAbstract not availableHannah Myles, Nicholas Myles, Nick A. Antic, Robert Adams, Madhu Chandratilleke, Dennis Liua, Jeremy Mercer, Andrew Vakulind, Andrew Vincent, Gary Wittert, Cherrie Galletl
Robert G. Gardner Collection (1937-2013)
No full textThe Robert G. Gardner collection contains class materials, correspondence, drafts of publications, lecture notes, photographs, research, sermons, speeches, and various personal papers. The bulk of these materials are grouped and arranged by year in Series 2. Series 1 contains biographical and bibliographic material prepared by Gardner himself, including a list of his major publications and speeches and a detailed autobiography written in 1990. Series 3 contains lecture notes, slides, tests, and syllabi from courses Gardner taught at Shorter College and elsewhere, arranged by course. Correspondence is arranged alphabetically in Series 4.Robert Granville Gardner was a Georgia Baptist archivist, historian, minister, and professor. He was born on April 26, 1924, in Lima, Ohio, to Ernest Granville and Gertrude Roberts Gardner and spent his childhood in Ohio, Michigan, and Oregon. After service in the United States Air Force (1943-46), he earned the Bachelor of Arts degree in Christianity at Mercer University in 1949, the Bachelor of Divinity degree from Duke University in 1952, and the Doctor of Philosophy degree in church history from Duke in 1957. He was ordained to the gospel ministry in 1947 and served as pastor of four churches in Georgia and North Carolina. He married Sara Anne Fargason, a Tift College alumna, in 1947, and together they were the parents of Susan and David. He taught for 37 years (1957-1994) in the Religion Department of Shorter College in Rome, Georgia, before retiring to Macon and working as Senior Researcher in Baptist History in Mercer University Library Archives from 1995 to 2012. He also taught as visiting professor at Philippine Baptist Theological Seminary (1967) and Southern Baptist Theological Seminary (1976, 1983). He was the author of six books on Baptist history as well as numerous pamphlets, articles, book chapters, and reviews. He was instrumental in the Georgia Baptist Historical Society and the Baptist History and Heritage Society, and he received numerous awards for his work in Baptist history
Mercer 5: A probable new globular cluster in the Galactic bulge
No full textWe present a detailed study of a dust-obscured Galactic star cluster Mercer 5 ([MCM2005b] 5) in an extremely crowded field in the Milky Way. Near-infrared (near-IR) photometry from United Kingdom Infrared Digital Sky Surveys (UKIDSS) and the Son of ISAAC on the New Technology Telescope (SofI/NTT), combined with near-IR spectroscopy also from SofI, indicates that it is almost certainly a Galactic globular cluster, located at the edge of the Galactic bulge. The cluster suffers ~9 mag of visual extinction, with strong evidence for an extinction gradient across the cluster. A simulation of the differential reddening in the cluster using empirical data from NGC 6539 (chosen because it had high signal-to-noise ratio data and low field star contamination) as a template mimics the observations extremely well. This simulation and other arguments are used to indicate that the most prominent clump of stars in the colour-magnitude diagrams is a horizontal branch clump. On this basis we conclude that the cluster is at a distance of ~5.5kpc and suffers from visual extinction ranging from ~8.5 to ~12.5 mag. Alternative explanations for its nature, such as a young cluster or an old open cluster, are much less likely, on the grounds of no visible main sequence or stars with IR excesses for the former and location versus lifetime arguments for the latter. © 2011 The Authors Monthly Notices of the Royal Astronomical Society © 2011 RAS
Mercer Law Review Vol. 036 Issue 02-033 pg. 0733 - O.C.G.A. 24-3-2: Evidence to Explain Conduct and Ascertain Motive Gets Disciplined
No full textSymposium: Closely-Held Businesses: Commen
Cementless stem stabilization after intraoperative fracture: A radiostereometric analysis
No full text© The Association of Bone and Joint Surgeons® 2009We present the case of a patient with intraoperative femoral fracture during THA, which was repaired using cerclage fixation and insertion of an hydroxyapatite-coated cementless stem. The patient was evaluated postoperatively using radiostereometry during a 2-year course, and despite a large amount of subsidence and rotation, stabilization occurred and was maintained by 6 months. By evaluating the pattern of stem migration after intraoperative fracture, this case shows, even in the presence of instability, a successful clinical outcome can be achieved using an hydroxyapatite-coated cementless stem. One or more of the authors (GM) have received funding from DePuy Orthopaedics Inc, Warsaw, IN, for this study. Each author certifies that his or her institution approved the reporting of this case report, that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained. This work was performed at Repatriation General Hospital.David Campbell, Graham Mercer, Kjell G. Nilsson, Stuart A. Callar
An experimental study of the environmental impacts of CCA-treated wood waste land application
No full textChromated copper arsenate (CCA) has been the most commonly used wood preservative in the UK; up until its partial ban in 2004. The preservative prolongs the service life of wood by 20-50 years by making it resistant to biological attack. As such, in-service CCA treated wood is expected to be a major component of the UK wood waste stream in the future. Concerns over the impact of the chemical constituents of this treatment on both the environment and human health have prompted the introduction of legislation to ensure that such waste is disposed of safely in Hazardous Waste Landfills. Despite this, studies have shown that this waste can still enter into the landscape mulch market due to inadequate detection methods and increasing societal pressures to recycle.A series of laboratory and field-based simulations were used to quantify leaching of copper, chromium and arsenic from CCA-treated wood waste mulch and evaluate the factors involved in promoting leaching. The distribution and behaviour of the metals in the soil column and leachate were also assessed. The samples generated in the study were analysed for a range of physico-chemical measurements, elemental and speciation concentrations.Results show that arsenic, chromium and copper leaches from CCA waste wood; at times to levels exceeding regulatory thresholds by two to three orders of magnitude. Furthermore, the more toxic and mobile species of arsenic (As III) and chromium (Cr VI) were detected in both soil and leachate samples. A mass balance was produced which demonstrated that CCA wood tends to leach on initial exposure to a leachant and also during weathering of the wood. When in contact with soil, metal(loid) transport is reduced due to complexation reactions. With higher water application or where the adsorption capacity of the soil is exceeded, the metal(loid)s are transported through the soil column as leachate. Overall, there was a loss of metal(loid)s from the system that could be due to loss of water, volatilisation of arsenic and plant uptake. Due to the toxicity and concentration levels of the leached elements identified in the current study, it is apparent that adverse environmental and human health impacts may result from direct and indirect exposure to the environmental media
An experimental study of the environmental impacts of CCA-treated wood waste land application
No full textChromated copper arsenate (CCA) has been the most commonly used wood preservative in the UK; up until its partial ban in 2004. The preservative prolongs the service life of wood by 20-50 years by making it resistant to biological attack. As such, in-service CCA treated wood is expected to be a major component of the UK wood waste stream in the future. Concerns over the impact of the chemical constituents of this treatment on both the environment and human health have prompted the introduction of legislation to ensure that such waste is disposed of safely in Hazardous Waste Landfills. Despite this, studies have shown that this waste can still enter into the landscape mulch market due to inadequate detection methods and increasing societal pressures to recycle.A series of laboratory and field-based simulations were used to quantify leaching of copper, chromium and arsenic from CCA-treated wood waste mulch and evaluate the factors involved in promoting leaching. The distribution and behaviour of the metals in the soil column and leachate were also assessed. The samples generated in the study were analysed for a range of physico-chemical measurements, elemental and speciation concentrations.Results show that arsenic, chromium and copper leaches from CCA waste wood; at times to levels exceeding regulatory thresholds by two to three orders of magnitude. Furthermore, the more toxic and mobile species of arsenic (As III) and chromium (Cr VI) were detected in both soil and leachate samples. A mass balance was produced which demonstrated that CCA wood tends to leach on initial exposure to a leachant and also during weathering of the wood. When in contact with soil, metal(loid) transport is reduced due to complexation reactions. With higher water application or where the adsorption capacity of the soil is exceeded, the metal(loid)s are transported through the soil column as leachate. Overall, there was a loss of metal(loid)s from the system that could be due to loss of water, volatilisation of arsenic and plant uptake. Due to the toxicity and concentration levels of the leached elements identified in the current study, it is apparent that adverse environmental and human health impacts may result from direct and indirect exposure to the environmental media
Verbesserung der Wundheilung durch wassergefiltertes Infrarot A (wIRA) bei Patienten mit chronischen venösen Unterschenkel-Ulzera einschließlich infrarot-thermographischer Beurteilung
No full textBackground: Water-filtered infrared-A (wIRA) is a special form of heat radiation with a high tissue-penetration and with a low thermal burden to the surface of the skin. wIRA is able to improve essential and energetically meaningful factors of wound healing by thermal and non-thermal effects.
Aim of the study: prospective study (primarily planned randomised, controlled, blinded, de facto with one exception only one cohort possible) using wIRA in the treatment of patients with recalcitrant chronic venous stasis ulcers of the lower legs with thermographic follow-up.
Methods: 10 patients (5 males, 5 females, median age 62 years) with 11 recalcitrant chronic venous stasis ulcers of the lower legs were treated with water-filtered infrared-A and visible light irradiation (wIRA(+VIS), Hydrosun® radiator type 501, 10 mm water cuvette, water-filtered spectrum 550–1400 nm) or visible light irradiation (VIS; only possible in one patient). The uncovered wounds of the patients were irradiated two to five times per week for 30 minutes at a standard distance of 25 cm (approximately 140 mW/cm2 wIRA and approximately 45 mW/cm2 VIS). Treatment continued for a period of up to 2 months (typically until closure or nearly closure of the ulcer). The main variable of interest was “percent change of ulcer size over time” including complete wound closure. Additional variables of interest were thermographic image analysis, patient’s feeling of pain in the wound, amount of pain medication, assessment of the effect of the irradiation (by patient and by clinical investigator), assessment of feeling of the wound area (by patient), assessment of wound healing (by clinical investigator) and assessment of the cosmetic state (by patient and by clinical investigator). For these assessments visual analogue scales (VAS) were used.
Results: The study showed a complete or nearly complete healing of lower leg ulcers in 7 patients and a clear reduction of ulcer size in another 2 of 10 patients, a clear reduction of pain and pain medication consumption (e.g. from 15 to 0 pain tablets per day), and a normalization of the thermographic image (before the beginning of the therapy typically hyperthermic rim of the ulcer with relative hypothermic ulcer base, up to 4.5°C temperature difference). In one patient the therapy of an ulcer of one leg was performed with the fully active radiator (wIRA(+VIS)), while the therapy of an ulcer of the other leg was made with a control group radiator (only VIS without wIRA), showing a clear difference in favour of the wIRA treatment. All mentioned VAS ratings improved remarkably during the period of irradiation treatment, representing an increased quality of life. Failures of complete or nearly complete wound healing were seen only in patients with arterial insufficiency, in smokers or in patients who did not have venous compression garment therapy.
Discussion and conclusions: wIRA can alleviate pain considerably (with an impressive decrease of the consumption of analgesics) and accelerate wound healing or improve a stagnating wound healing process and diminish an elevated wound exudation and inflammation both in acute and in chronic wounds (in this study shown in chronic venous stasis ulcers of the lower legs) and in problem wounds including infected wounds. In chronic recalcitrant wounds complete healing is achieved, which was not reached before. Other studies have shown that even without a disturbance of wound healing an acute wound healing process can be improved (e.g. reduced pain) by wIRA.
wIRA is a contact-free, easily used and pleasantly felt procedure without consumption of material with a good penetration effect, which is similar to solar heat radiation on the surface of the earth in moderate climatic zones. Wound healing and infection defence (e.g. granulocyte function including antibacterial oxygen radical formation of the granulocytes) are critically dependent on a sufficient energy supply (and on sufficient oxygen). The good clinical effect of wIRA on wounds and also on problem wounds and wound infections can be explained by the improvement of both the energy supply and the oxygen supply (e.g. for the granulocyte function). wIRA causes as a thermal effect in the tissue an improvement in three decisive factors: tissue oxygen partial pressure, tissue temperature and tissue blood flow. Besides this non-thermal effects of infrared-A by direct stimulation of cells and cellular structures with reactions of the cells have also been described. It is concluded that wIRA can be used to improve wound healing, to reduce pain, exudation, and inflammation and to increase quality of life.Hintergrund: Wassergefiltertes Infrarot A (wIRA) ist eine spezielle Form der Wärmestrahlung mit hoher Gewebepenetration bei geringer thermischer Oberflächenbelastung. wIRA vermag über thermische und nicht-thermische Effekte wesentliche und energetisch bedeutsame Faktoren der Wundheilung zu verbessern.
Ziel der Studie: prospektive Studie (primär randomisiert, kontrolliert, verblindet geplant, de facto mit einer Ausnahme nur eine Kohorte möglich) mit wassergefiltertem Infrarot A (wIRA) in der Therapie von Patienten mit therapierefraktären chronischen venösen Unterschenkel-Ulzera mit thermographischer Verlaufskontrolle.
Methoden: 10 Patienten (5 Männer, 5 Frauen, Median des Alters 62 Jahre) mit 11 therapierefraktären chronischen venösen Unterschenkel-Ulzera wurden mit wassergefiltertem Infrarot A und sichtbarem Licht (wIRA(+VIS), Hydrosun®-Strahler Typ 501, 10 mm Wasserküvette, wassergefiltertes Spektrum 550–1400 nm) oder mit sichtbarem Licht (VIS; nur bei einem Patienten möglich) bestrahlt. Die unbedeckten Wunden der Patienten wurden zwei- bis fünfmal pro Woche über bis zu 2 Monate (typischerweise bis zum Wundschluss oder Fast-Wundschluss des Ulkus) für jeweils 30 Minuten mit einem Standardabstand von 25 cm bestrahlt (ungefähr 140 mW/cm2 wIRA und ungefähr 45 mW/cm2 VIS). Hauptzielvariable war die „prozentuale Änderung der Ulkusgröße über die Zeit“ einschließlich des kompletten Wundschlusses. Zusätzliche Zielvariablen waren thermographische Bildanalyse, Schmerzempfinden des Patienten in der Wunde, Schmerzmittelverbrauch, Einschätzung des Effekts der Bestrahlung (durch Patient und durch klinischen Untersucher), Einschätzung des Patienten des Gefühls im Wundbereich, Einschätzung der Wundheilung durch den klinischen Untersucher sowie Einschätzung des kosmetischen Zustandes (durch Patienten und durch klinischen Untersucher). Für diese Erhebungen wurden visuelle Analogskalen (VAS) verwendet.
Ergebnisse: Die Studie ergab eine vollständige oder fast vollständige Abheilung der Unterschenkel-Ulzera bei 7 Patienten sowie eine deutliche Ulkusverkleinerung bei 2 weiteren der 10 Patienten, eine bemerkenswerte Minderung der Schmerzen und des Schmerzmittelverbrauchs (von z.B. 15 auf 0 Schmerztabletten täglich) und eine Normalisierung des thermographischen Bildes (vor Therapiebeginn typischerweise hyperthermer Ulkusrandwall mit relativ hypothermem Ulkusgrund, bis zu 4,5°C Temperaturdifferenz). Bei einem Patienten wurde ein Ulkus an einem Bein mit dem Vollwirkstrahler (wIRA(+VIS)) therapiert, während ein Ulkus am anderen Bein mit einem Kontrollgruppenstrahler (nur VIS, ohne wIRA) behandelt wurde, was einen deutlichen Unterschied zugunsten der wIRA-Therapie zeigte. Alle aufgeführten VAS-Einschätzungen verbesserten sich während der Bestrahlungstherapie-Periode sehr stark, was einer verbesserten Lebensqualität entsprach. Ein kompletter oder fast kompletter Wundschluss wurde nur bei Patienten mit peripherer arterieller Verschlusskrankheit, Rauchern oder Patienten mit fehlender venöser Kompressionstherapie nicht erreicht.
Diskussion und Schlussfolgerungen: wIRA kann sowohl bei akuten Wunden als auch bei chronischen Wunden (in dieser Studie für chronische venöse Unterschenkelulzera gezeigt) und Problemwunden einschließlich infizierter Wunden Schmerzen deutlich mindern (mit eindrucksvoller Abnahme des Schmerzmittelverbrauchs) und die Wundheilung beschleunigen oder einen stagnierenden Wundheilungsprozess verbessern sowie eine erhöhte Wundsekretion und Entzündung mindern.
Bei chronischen therapierefraktären Wunden werden vollständige Abheilungen erreicht, die zuvor nicht erreicht wurden. Andere Studien haben sogar ohne Wundheilungsstörung eine Verbesserung (z.B. Schmerzreduktion) der akuten Wundheilung durch wIRA gezeigt.
wIRA ist ein kontaktfreies, verbrauchsmaterialfreies, leicht anzuwendendes, als angenehm empfundenes Verfahren mit guter Tiefenwirkung, das der Sonnenwärmestrahlung auf der Erdoberfläche in gemäßigten Klimazonen nachempfunden ist.
Wundheilung und Infektionsabwehr (z.B. Granulozytenfunktion einschließlich antibakterieller Sauerstoffradikalbildung der Granulozyten) hängen ganz entscheidend von einer ausreichenden Energieversorgung (und von ausreichend Sauerstoff) ab. Die gute klinische Wirkung von wIRA auf Wunden und auch auf Problemwunden und Wundinfektionen lässt sich über die Verbesserung sowohl der Energiebereitstellung als auch der Sauerstoffversorgung (z.B. für die Granulozytenfunktion) erklären. wIRA bewirkt als thermischen Effekt im Gewebe eine Verbesserung von drei entscheidenden Faktoren: Sauerstoffpartialdruck im Gewebe, Gewebetemperatur und Gewebedurchblutung. Daneben wurden auch nicht-thermische Effekte von Infrarot A durch direkte Reizsetzung auf Zellen und zelluläre Strukturen mit Reaktionen der Zellen beschrieben.
Es wird geschlossen, dass wIRA verwendet werden kann, um Wundheilung zu verbessern, Schmerzen, Sekretion und Entzündung zu reduzieren und die Lebensqualität zu steigern
Improving the health of people with multimorbidity: the need for prospective cohort studies
No full textThe dramatic rise in long-term conditions (LTCs) represents a major challenge for individuals, families, and health care systems worldwide. Due to the scale of this rise, the management of patients with LTCs largely falls within the domain of primary rather than secondary care, at least in countries with well-developed primary care systems. For example, in the UK, which has a comprehensive primary care system based around general practice (trained family physicians working in multidisciplinary teams) and funded by the National Health Service (NHS), primary care contacts account for around 90% of the total activity of the NHS, and patients with LTCs account for 80% of general practice consultations. Effective primary care and community-based management of people with LTCs is thus a top priority
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