196,355 research outputs found

    Quercus x caroppoi Medagli, Turco, Albano & Accogli, a new oak's hybrid from the Salento

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    ItGli Autori descrivono una nuova entità del genere Quercus di probabile origine ibrida: Quercus x caroppoi, rinvenuta nel Salento (Carpignano Salentino, Lecce) che sembrerebbe originata dall'ibridazione tra cerro (Quercus cerris L.) e quercia spinosa (Quercus coccifera L. subsp. calliprinos Webb). Si tratta del primo ritrovamento in assoluto di tale ibrido. Il portamento dell'albero appare con chioma di forma slanciata (come in Q. cerris) e non globosa (come in Q. coccifera), la forma della lamina fogliare appare dentato-lobata come in Q. cerris, ma sempreverde come in Q. coccifera, inoltre le foglie sono meno coriacee e meno lucide di Q. calliprinos, con mucroni non pungenti. Le ghiande somigliano a quelle di Q. calliprinos, ma hanno cupule con squame meno rigide e non pungenti. Un caso che presenta molte analogie è quello del rinvenimento di Quercus thracica Stefanov & Nedjalkov in Bulgaria nel 1955, presunto ibrido tra Quercus coccifera L. subsp. calliprinos Webb e Q. trojana Webb., molto affine morfologicamente a Q. xcaroppoi, rinvenuto in un unico esemplare bicormico. Purtroppo, in questo caso, dopo la scomparsa dell'unico esemplare individuato avvenuta nel 2010, tale taxon è stato dichiarato estinto.EnAuthors describe a new taxon that belongs to genus Quercus L. probably of hybrid origin. Quercus x caroppoi was found in Salento (Carpignano Salentino, Lecce), it would seem to be originated from hybridization between Turkey oak (Quercus cerris L.) and Kermes oak (Quercus coccifera L. subsp. calliprinos Webb). This is the first ever discovery of this hybrid. The discovery of the new hybrid took place 13th September 2012 along the provincial road S.P. 3, Carpignano Salentino-Borgagne (LE), near a dry-stone wall bordering an olive grove. Q. x caroppoi is an abundantly fruiting tree of about 8-8,5 m high (Fig. 1), with a slim canopy (as in Q. cerris) and not globular (as in Q. coccifera subsp. calliprinos). It has a greyish bark, smooth with slightly accentuated longitudinal striations (Fig. 2) and a bicormic appearance, as it has two distinct trunks about one meter apart, starting from the ground to canopy, apparently, two distinct and twin trees (main shoots) and numerous small basal suckers, which give it a densely bushy appearance (Fig. 3). Leaves have pubescent petioles, with a generally crinkled leaf blade, almost never flat, often asymmetrical in shape, lanceolate-acute as in Q. cerris (elliptical or obovate in Q. coccifera), evergreen, rather shiny and rough to the touch, (but less shiny than respect the leaves of Q. coccifera) (Fig. 4); coriaceous (but less than respect to Q. coccifera) with a glabrous and darker upper leaf page and a lighter lower leaf page (Fig. 5) with evident leaf veins (they are just noticeable in Q. coccifera) all with 4-6 toothed and mucronate lobes per side and an acute and mucronate apex as in Q. cerris, but with non-rigid and pungent mucrons as in the Q. coccifera subsp. calliprinos, with 4-6 dentate and unequal lobes per side. Leaf are flattened at the apex where they have an apical mucron. Cupule covers from half to one third of the acorn; they look similar to that of Q. coccifera calliprinos, but with stiff scales and pointed apex, arched towards the peduncle. The cupules are more delicate, slightly thinner, and less lignified if compared to those of Q. coccifera (Fig. 6). An interesting remark is the biennal fruiting cycle of Q. x caroppoi, as it presents simultaneously acorns at initial development associated with acorns close to maturity (Fig. 7). This biennality in the development of acorns is common to both Thorny oak and Turkey oak. During samplings at the base of the tree, numerous germinating acorns (Fig. 8) and several plants born spontaneously from germinated acorns were observed, which, however, due to the lack of suitable spaces and to interventions of weeding in the adjacent olive grove, they cannot develop undisturbed (Fig. 9). At the Botanical Garden of the University of Salento acorns where seeded and germinating power was analysed (Fig. 10). Acorns show a germinative power of about 52% (6 months after seeding), unlike experiences concerning Quercus coccifera subsp. calliprinos which showed a higher germination around 80-95% in Salento. The seedlings show a strong resemblance to the mother plant, highlighting strongly toothed and mucronate leaves (Fig. 11). It would seem that the specimen is predominantly self-pollinated, which promote conservation of the features that belong to the mother plant; this assumption is also due to the considerable distance of Q. caroppoi from spontaneous specimens of thorny oak. A case that has many similarities is related to the discovery of Q. thracica Stefanov & Nedjalkov, a presumed hybrid between Q. cerris e Q. trojana Webb. that was found in Bulgaria as a bicormic plant, with morphological characteristics very similar to Q. x caroppoi. Unfortunately, in this case, after the death of the only plant described in 2010, this taxon was declared extinct

    Ciprofloxacin-resistant, CTX-M-15-producing Escherichia coli ST131 clone in extraintestinal infections in Italy

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    Quinolone and β-lactam resistance mechanisms and clonal relationships were characterized among Escherichia coli isolates resistant to ciprofloxacin and extended-spectrum cephalosporins associated with human extra-intestinal infections in Rome. The E. coli. ST131 clone was found to be prevalent. This clone invariably carried a specific pattern of substitutions in the topoisomerase genes and all isolates but one produced CTX-M-15. One ST131 isolate produced SHV-12. The new ST131 variant described here is of particular concern because it combines fluoroquinolone resistance and chromosomally encoded CTX-M-15. © 2010 The Authors. Journal Compilation © 2010 European Society of Clinical Microbiology and Infectious Diseases

    IncI1 plasmids associated with the spread of CMY-2, CTX-M-1 and SHV-12 in Escherichia coli of animal and human origin

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    AbstractFourteen plasmids carrying blaCTC-M-1, blaSHV-12 or blaCMY-2 genes from Escherichia coli of both avian and human origin were analysed. IncI1 plasmids were largely predominant. Plasmid mutilocus sequence typing and comparative analysis revealed that the blaCMY-2-ST12-IncI1 plasmids from avian E. coli were identical to those previously found in Salmonella from humans, but different to those associated with human E. coli. The IncI1-ST3 plasmids carrying blaCTX-M-1 or blaSHV-12 were related to those previously identified in avian E. coli, but different to those identified in human E. coli. Overall, no plasmids shared by E. coli of both origin (human/avian) were identified; however, further investigations are needed

    Therapeutic education and physical activity are feasible and safe in hematologic cancer patients referred to chemotherapy: results of a randomized controlled trial

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    Purpose: Although over 60% of patients with hematologic cancer report distressing fatigue, they often do not receive recommendations on fatigue management strategies. The aim of this pilot study was to estimate the feasibility of therapeutic education and physical activity (TEPA) by measuring the patients’ adherence to this multidimensional intervention. The secondary aim was to estimate the impact of TEPA on clinical outcomes. Methods: Patients with hematologic cancer participated in this single-center, open-label, randomized controlled trial. The control group (CG) received two educational group sessions on fatigue and physical activity. The experimental group (EG) received the two educational sessions plus six weekly individual sessions aimed at implementing a personalized physical exercise program. Follow-ups were at 1, 3, and 7 months. Results: Forty-six patients referred to chemotherapy were included, corresponding to 54% of recruitment rate. Adherence reached 90% in the EG and 68% in the CG. Most patients (65% in EG and 64% in CG) attended a minimum of 80% of the planned sessions. Overall retention rate was 87% (85% in EG and 91% in CG). No adverse events were registered. No between-group differences were detected in fatigue (FACIT-F), psychological distress (NCCN Distress Thermometer), QoL (EORTC QLQ-C30), or functional exercise capacity (TUG test and 6MWT). Adherence to an active lifestyle, measured by a semi-structured interview, increased from 56.5 to 84% in the EG at 7 months (p = 0.02), whereas it decreased slightly in the CG (from 47.8 to 42.9%). Conclusion: Multidimensional rehabilitation interventions are feasible and safe in this population, and larger trials should focus on the efficacy of such approaches on clinically relevant outcomes. Trial registration: ClinicalTrials.gov Identifier: NCT03403075

    Therapeutic Education and Physical Activity to Support Self-management of Cancer-related Fatigue in Hematologic Cancer Patients: Protocol of a Feasibility Randomized Controlled Trial

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    Introduction: Hematologic malignancies account for nearly 8% of new cancer diagnosis in Italy. Cancer-related fatigue (CRF) is one of the most distressing symptoms reported by patients with cancer. As CRF has a multifactorial etiology, physical activity and therapeutic education may be beneficial for managing CRF, both during and after cancer treatment. However, there is a lack of evidence specific to hematologic malignancies. This paper describes the protocol of a feasibility study on Therapeutic Education and Physical Activity (TEPA) intervention to support self-management of CRF in patients with hematologic malignancies. Methods: TEPA was addressed to newly diagnosed adult individuals with hematologic malignancy able to take part in a rehabilitation programme at the AUSL-IRCCS of Reggio Emilia. The protocol was developed in 2 phases. Phase I was an observational cohort study involving a convenience sample of 10 participants with the aim to evaluate the feasibility of the assessment schedule and to register longitudinal clinical data regarding CRF (FACIT-F), psychologic distress (NCCN Distress Thermometer), QoL (EORTC QLQ-C30), physical performance (TUG and 6MWT) and habitual level of physical activity during first months after diagnosis. Phase II (underway) is a feasibility randomized controlled trial (TEPA) involving a convenience sample of 40 participants and comparing 2 parallel active interventions (Therapeutic Education versus Therapeutic Education and Physical Activity) on top of usual care. The primary aim is to estimate the feasibility of TEPA, measured by the adherence rate to the intervention. Secondary aims are: to estimate the effect size of TEPA in terms of changes in CRF, psychological distress, QoL, physical performance and habitual level of physical activity (measured as in Phase I); to collect patient satisfaction, perception of usefulness of the TEPA intervention and data on long-term adherence to an active lifestyle. Data are collected in both phases at the time of diagnosis and then at 1-, 3- (completion of intervention) and 7-month follow-up. Discussion: Data on feasibility and effect size of TEPA will be analyzed upon completion of Phase II, allowing us to design a large, adequately powered RCT to verify the effectiveness of this intervention on CRF management in patients with hematologic cancer. Trial registration: clinicaltrials.gov; Trial registration number: NCT0340307
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