87,814 research outputs found
Indice dei nomi (a cura di F. C. Abramo, M. Fadini, C. Polli)
No full textIndice dei nomi del volume VIII di «Ticontre» (a cura di Federica Claudia Abramo, Matteo Fadini, Chiara Polli)Indice dei nomi del volume VIII di «Ticontre» (a cura di Federica Claudia Abramo, Matteo Fadini, Chiara Polli)Indice dei nomi del volume VIII di «Ticontre» (a cura di Federica Claudia Abramo, Matteo Fadini, Chiara Polli)Indice dei nomi del volume VIII di «Ticontre» (a cura di Federica Claudia Abramo, Matteo Fadini, Chiara Polli
Skin organ culture: potential applications in wound healing research
No full textIntroduction: Short-term organ culture of skin explants is a useful model for the study of various aspects of skin biology. This study aimed to test the robustness of a canine skin organ culture model and its ability to respond to selected pharmacological stimuli.
Material and methods: Ki67-positive proliferating keratinocytes, epidermal thickness, expression of selected cytokeratins and epithelial tongue formation were evaluated in Epidermal Growth Factor (EGF)-stimulated cultures, with and without treatment with Dexamethasone (DMS). Mast cell (MC) degranulation, histamine release and early local inflammatory response in compound 48/80-stimulated cultures were evaluated after treatment with the endocannabinoid-like Palmitoylethanolamide in the form ultramicron-sized particles (PEA-um).
Results: DMS treatment significantly reduced both EGF-induced keratinocyte proliferation and epidermal thickening. Conversely, DMS enhanced the length of EGF-induced re-epithelializing tongues at the edge of the culture.
Treatment with PEA-um significantly counteracted compound 48/80-induced increase in the percentage of degranulating MCs. PEA-um also reduced by one-half the histamine content in the culture medium from compound 48/80-stimulated cultures. Finally, PEA-um significantly limited the compound 48/80-induced early inflammatory response, i.e., vasodilation.
Discussion: Our findings demonstrate the potential use of a full-thickness canine skin organ culture model for the study of skin physiology and response to selected stimuli and treatments. In this respect the evaluation of re-epithelialization mechanisms and early inflammatory response could be of great interest in the field of wound healing research
La misurazione della produttività scientifica delle università italiane attraverso una metodologia bibliometrica non-parametrica
No full text
Assessing the accuracy of the h and g indexes for measuring researchers’ productivity
No full textBibliometric indicators are increasingly used in support of decisions about recruitment, career advancement, rewards, and selective funding for scientists. Given the importance of the applications, bibliometricians are obligated to carry out empirical testing of the robustness of the indicators, in simulations of real contexts. In this work, we compare the results of national-scale research assessments at the individual level, based on the following three different indexes: the h-index, the g-index, and “fractional scientific strength” (FSS), an indicator previously proposed by the authors. For each index, we construct and compare rankings lists of all Italian academic researchers working in the hard sciences during the period 2001–2005. The analysis quantifies the shifts in ranks that occur when researchers' productivity rankings by simple indicators such as the h- or g-indexes are compared with those by more accurate FSS
The suitability of h and g indexes for measuring the productivity of research institutions
No full textCarrión, F., Reinoso Naranjo, V., Ramírez Kuri, P., Abramo P. y Corti, M. (Eds.) (2023). Ciudad, género y espacio doméstico. Tomo 1. Ecuador: FLACSO
No full textCarrión, F.; Reinoso Naranjo, V.; Ramírez Kuri, P.; Abramo P. y Corti M. (Eds.), (2023), Ciudad, género y espacio doméstico. Tomo 1. FLACSO, Ecuador. 
- …
