452 research outputs found
‘Born to Shop’: Malls, Dream-Worlds and Capitalism
Get PDFIt has been twenty years since the fall of the Berlin Wall, and a new generation, untouched by the previous communist regimes, has come to adulthood throughout the post-communist world. The Iulius Group’s logo – ‘Born to shop!’ – suggests that these are born shoppers: the capitalist babies of Central and Eastern Europe who are sustaining the largest growth in retail and shopping malls in Europe. With no living memory of shortages, queuing, or government restrictions, they know only the limit of their own – or their parents’ – pocket/credit. Their world could not be more different from the one that their parents and grandparents experienced: both the abundance of goods and services, as well as the opulent settings under which they are now sold, offer striking visual contrasts to the not-so-distant past. In addition, the very experience of consumption is directly connected to the way in which the current social fabric – and new social divisions within it – is interwoven with the physical and architectural changes taking place in the urban setting
Open Questions on Stress in Arabic: Some Sociophonological Interpretations
No full textThe paper provides a brief overview of the stress systems in some varieties of Arabic and recommends some diachronic reflections involving also connections between Aramaic and Arabic, on the base of a broader research project on the history of the typological division between Eastern and North African Arabic dialects
Assessing children’s syntactic proficiency through a sentence repetition task: A comparison between cochlear implanted children and typically developing children
No full textCochlear implants (CIs) can provide proper linguistic input to children with severe to profound sensorineural hearing loss. However, despite an early diagnosis and intervention, and the development of lexical skills and speech perception similar to typically developing age peers, children with CIs still show a delay in the processing of movement-derived structures. Following previous studies on deaf or hard-of-hearing Hebrew-speaking children, this study provides first data on the repetition of movement-derived syntactically complex structures in Italian-speaking children with CIs. Results showed that children with CIs performed poorer than their typically developing age peers and showed many difficulties in all the structures characterised by a complex derivation. Interestingly, both groups showed difficulties in the production of relative clauses
That-Relatives and Pied-Piping Relatives in Italian-Speaking Children with and without Cochlear Implants: Evidence from a Production Task and a Repetition Task
No full textThe aim of this work is to investigate the use of subject (SR), direct object (OR), and oblique (genitive and prepositional) relative clauses in Italian in a group of children with cochlear implants (CI) and a group of hearing chil-dren.
Our data have shown that in the production of that-relatives, the NH group performed significantly better than the CI group. The poor performance of the experimental group may be caused by the late exposure to language, although children were promptly diagnosed with hearing loss and are fitted with HA within the first year of age
Global ethnic and geographic differences in the clinical presentations of anti-neutrophil cytoplasm antibody–associated vasculitis
Get PDF© The Author 2017. Objectives. There are few data on clinical profiles of ANCA-associated vasculitis (AAV) in different ethnic populations. The aim of this study was to examine the differences in the ANCA type and clinical features of AAV between populations using the Diagnostic and Classification Criteria in Vasculitis Study (DCVAS) dataset. Methods. The DCVAS is an international, multicentre, observational study recruiting in 133 sites. Eight ethnic categories were analysed: Northern European, Caucasian American, Southern European, Middle Eastern/Turkish, Chinese, Japanese, Indian subcontinent and other. ANCA type was categorized as myeloperoxidase (MPO), PR3 and ANCA negative. Organ system involvement was recorded using a standard dataset. Differences were analysed by chi-squared tests using a Bonferroni correction and logistic regression (adjusting for age and sex). Northern European was the reference population. Results. Data from 1217 patients with AAV were available and the 967 (79.5%) patients recruited by rheumatology departments were analysed to reduce confounding by recruitment specialty. There were differences in ANCA type between ethnic categories (P < 0.001): MPO-ANCA was more common than PR3-ANCA in Japanese, Chinese and Southern Europeans; PR3-ANCA was more common in the other groups. Compared with Northern Europeans, Japanese had a nearly 60-fold increased chance of having MPO-ANCA (vs PR3-ANCA) [odds ratio (OR) 59.2 (95% CI 8.0, 440.7), P < 0.001] and Chinese had a nearly 7-times increased chance [OR 6.8 (95% CI 2.6, 17.8), P < 0.001]. Ophthalmologic and otorhinolaryngologic involvement were less common in Japanese and Chinese populations than Northern Europeans; otherwise, there were few differences in organ involvement between ethnic groups. Conclusion. This study confirms the previously observed differential occurrence of MPO-AAV and PR3- AAV between different ethnic groups
THE INTEGRATION OF YOUNG ECONOMISTS ON THE LABOUR MARKET. THE PROFESSION OPTION - A DECISION FOR CAREER AND FOR A LIFESTYLE
Get PDFKnowing the importance of the integration process of graduates of higher economic studies on a labour market that is becoming more and more demanding, as well as the fact that professional objectives realistic defined represent an essential demand of performance, the present paper aims to determine the relevance of personal decision capacities as a favouring factor of a concrete career option for economist students. Our research is based on information and statistical data obtained through applying tests and questionnaires on economist students from licence and master studies form three universities: University of Oradea, The West University of Timişoara and "Ştefan cel Mare" University of Suceava, in the project called PRACTeam "The practice of economist students. Inter-regional partnership on the labour market between universities and the business environment" Project co-financed through the Social European Fund, Through the Operational Program Human Resource Development 2007 - 2013 - "Invest in people!". In essence we leave from the premises that the professional option reflects a specific side of individual's personality which does not choose only for a certain occupation but, implicitly for a certain lifestyle. As a diagnosis approach we assume axiomatic the thesis according to which the high level of congruence between the individual psychological availabilities and the occupational environment raises the satisfaction chance and professional success. The approach that we submit is an interdisciplinary one, as well as the research team formed of two economists and a psychologist. Our study proposes to identify the correlation between the individual decision ability of the subject and the compatibility between a specific interests set of abilities identified on the basis of individual tests. Also, on the basis of processing the results obtained of economist students at the personality tests, we will try to argument explaining the option of some subjects for professions that demand individual qualities that their personality does not imply at the level asked.labour market, profession option, economist students, career
Enhanced Formation and Disordered Regulation of NETs in Myeloperoxidase-ANCA-Associated Microscopic Polyangiitis.
Get PDFMicroscopic polyangiitis (MPA) is an ANCA-associated vasculitis that affects small vessels, especially renal glomeruli. We recently demonstrated that the abnormal formation and impaired degradation of neutrophil extracellular traps (NETs) may be crucially involved in the generation of myeloperoxidase (MPO)-ANCA and subsequent development of MPA. This study assessed the formation and regulation of NETs in patients with MPO-ANCA-associated MPA. Peripheral blood samples were obtained from 38 patients with MPO-ANCA-associated MPA, 23 patients with systemic lupus erythematosus (SLE), and 8 healthy controls. IgG eluted from MPO-ANCA-associated MPA sera demonstrated the highest ability to induce NETs, and this ability correlated with disease activity and paralleled ANCA affinity for MPO. Moreover, addition of recombinant human MPO to these IgG samples reduced NET induction. Additionally, MPO-ANCA-associated MPA sera exhibited lower rates of NET degradation that recovered partially upon depletion of IgG. The activity of DNase I, an important regulator of NETs, was also lower in MPO-ANCA-associated MPA and SLE sera. IgG depletion from MPO-ANCA-associated MPA sera partially restored the rate of NET degradation, and addition of DNase I synergistically enhanced this restoration. Addition of anti-MPO antibodies did not inhibit DNase I activity, and some MPO-ANCA-associated MPA sera contained anti-NET antibodies at levels not correlated with MPO-ANCA titers, suggesting the involvement of unidentified autoantibodies as well. The collective evidence suggests a vicious cycle involving MPO-ANCA and the regulation of NETs could be critically involved in the pathogenesis of MPO-ANCA-associated MPA
STUDY OF EPHEMEROPTERA IN WARM SOMES GORGES
Get PDFEphemeroptera group is unique in the world of insect wing, because they have two adult stages. The first, called subimago, is developed from the final larva stage. Drift phenomenon, found to larvae favor the popullation of new area. Larva of Ephemeroptera occupies an important place in the food chain, most of which are primary consumers. Larva and adults are also a consistently reservoir of nutrient for predators (fish, birds and spiders).Given their specific requirement of certain species Ephemeroptera bodies are excellent bio-indicators.
SPECIFICATION
By the article: STUDY OF EPHEMEROPTERA IN WARM SOMES GORGES, publiched in Agricultura – Ştiinţă şi practică, nr. 1-2 (69-701)/2009
Autori: Anca Dafina COVACI, Ion OLTEAN, Teodora FLORIAN
Taking into consideration that the data included in this article do not respect the deontological rules of scientific research, we recommend that the present work should not be regarded as a genuine paper. The raw data from this article belong to the aquatic ecology team from the Babeş-Bolyai University, Faculty of Biology and Geology (Associate Professor Laura Momeu, Ph.D.; Mirela Cîmpean, Ph.D.; Anca Avram, Ph.D. student and Teaching Assistant Karina Battes, Ph.D.), and they were used without permission by PhD student Anca Covaci.
Drd. Anca Dafina COVAC
Pathogenesis and therapeutic interventions for ANCA-associated vasculitis.
Get PDFAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) affects systemic small vessels and is accompanied by the presence of ANCAs in the serum. This disease entity includes microscopic polyangiitis, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis and drug-induced AAV. Similar to other autoimmune diseases, AAV develops in patients with a predisposing genetic background who have been exposed to causative environmental factors. The mechanism by which ANCAs cause vasculitis involves ANCA-mediated excessive activation of neutrophils that subsequently release inflammatory cytokines, reactive oxygen species and lytic enzymes. In addition, this excessive activation of neutrophils by ANCAs induces formation of neutrophil extracellular traps (NETs). Although NETs are essential elements in innate immunity, excessive NET formation is harmful to small vessels. Moreover, NETs are involved not only in ANCA-mediated vascular injury but also in the production of ANCAs themselves. Therefore, a vicious cycle of NET formation and ANCA production is considered to be involved in the pathogenesis of AAV. In addition to this role of NETs in AAV, some other important discoveries have been made in the past few years. Incorporating these new insights into our understanding of the pathogenesis of AAV is needed to fully understand and ultimately overcome this disease
ANCA-negative pauci-immune crescentic glomerulonephritis
No full textCrescentic glomerulonephritis is a severe form of glomerular injury that is characterized by disruption of the glomerular basement membrane, cellular proliferation within Bowman space, and (often) fibrinoid necrosis. Pauci-immune crescentic glomerulonephritis, so called because it involves little or no glomerular immunoglobulin deposition, is one of the most common causes of rapidly progressive glomerulonephritis. in the majority of patients, pauci-immune crescentic glomerulonephritis is a manifestation of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. However, some patients with pauci-immune crescentic glomerulonephritis lack ANCAs. This review compares the prevalence, clinical manifestations, histopathology, and outcomes of ANCA-negative pauci-immune crescentic glomerulonephritis with those of ANCA-positive disease. we also discuss the possible pathogenesis of ANCA-negative pauci-immune crescentic glomerulonephritis, paying particular attention to the mechanisms and role of neutrophil activation
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