1,721,005 research outputs found
Clinical evidences of urea at high concentration on skin and annexes
Full text linkhe antiproliferative, keratolytic, moisturizing and emollient properties of urea are already known. Clinical evidences of urea at high concentration indicate its important role in the presence of hyperkeratosis that, if severe or localized in specific body areas, may cause discomfort to the patient and may interfere with absorption of topical drugs, delaying response to treatment. Other important uses of urea at high concentration are on the scalp and on nail plate. The keratolytic effect of urea is well-tolerated and virtually free from side effects. Compliance with topical therapy is directly related to the aesthetic and sensory acceptability of a topical agent that may considerably vary in odour, spreadability and post-application residue
TREATMENT OF NAIL PSORIASIS WITH COMBINATION OF TOPICAL TAZAROTENE AND UREA-CONTAINING NAIL LACQUER: PRELIMINARY EXPERIENCE ON 6 PATIENTS
No full textPSORIASI OF THE NAILS IS VERY COMMON, AFFECTING UP TO 80% OF PATIENTS WITH SKIN LESIONS, AND ALSO OCCURRING AS ISOLATED NAIL DISEASE. NAIL PSORIASIS IS MORE COMMON IN PATIENTS WITH SEVERE DISEASE AND IN THOSE WITH PSORIATIC ARTHOPATHY AND IS CONSIDERED BY THE NAIL DYSTROPHIES, AND OFTEN FRUSTATED BY PREVIOUS INEFFECTIVE OR POORLY TOLERATED TREATMENTS. COMBINATION OF TOPICAL DRUGS AND PRODUCTS WITH DIFFERENT MODE OF ACTION AND MODALITY OF APPLICATION IS PROBABLY THE BEST WAY TO OBTAIN IMPROVEMENT OF NAIL PSORIASIS, IN ORDER TO TARGET BOTH NAIL BED AND NAIL MATRIX SYMPTON. THE COMBINED TREATED WITH TOPICAL TAZAROTENE AND UREA CONTANING NAIL LACQUER IS A VALID THERAPEUTIC OPTION IN THESE PATIENT
WHEN THE NAIL APPERANCE PLAYS TRICKS: A CASE OF LONGITUDINAL MELANONYCHIA
No full textA paediatric nail consultation is often required to reduce parents’ concerns regarding their child’s abnormal nail appearance. Nail pigmentation in children is a dermatological challenge because guidelines are not standardised, causing many doubts for dermatologists. In general, the majority of cases of melanonychia are benign in children and nail melanoma cases are very rare. However, alarming clinical and dermoscopic features can be observed, requiring nail surgery to confrm a diagnosis. Here, we present a case of longitudinal melanonychia in a teenager with atypical signs and a good prognosis
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
NAIL APPARATUS MELANOMA: DERMOSCOPIC AND HISTOPATHOLOGIC CORRELATIONS ON A SERIES OF 23 PATIENTS FROM A SINGLE CENTER.
No full textBackground Nail apparatus melanoma (NAM) is an uncommon tumour, and there are few studies focused on its der-
moscopic features.
Objective The aims of our study were to evaluate the diagnostic accuracy of dermoscopy in NAM. A diagnostic algo-
rithm for adult patients with suspected NAM is proposed.
Methods We collected NAM dermoscopic images of patients with a proven histopathology from 2008 until 2015. Clini-
cal and dermoscopic images were blindly examined by two dermatologists, and correlations between histopathological
aspects and dermoscopic features were investigated.
Results We retrospectively collected NAM dermoscopic images associated with a proven histopathology of 23 Cau-
casian patients. Only cases with available both preoperative dermoscopic images and bioptic specimens were included.
Seventeen women and six men were included. The mean age at diagnosis was 63 years (range 18–92).
Conclusion We created an algorithm to indicate the correct way to follow an adult patient with suspected NAM. This
algorithm may ameliorate management in case of suspected NAM and possibly facilitate an early diagnosi
- …
