1,720,982 research outputs found
Coronary artery disease in joung patients with systemic lupus erythematosus: two case reports.
Apical hypertrophic cardiomyopathy and atrial septal defect: Part of a multi-organ syndrome?
Thallium-201 myocardial perfusion imaging after aortocoronary bypass surgery in patients treated with sulodexide versus patients treated with ASA-dipyridamole
The aim of this investigation was to compare the preventive effect of sulodexide, a glycosaminoglycan drug, tested versus ASA-dipyridamole association, on the occlusion of venous aortocoronary bypass. A group A of 23 patients, for a total of 22 anastomosis with internal mammary artery and 46 venous bypass, was treated with sulodexide 500 USL/day. A group B of 18 patients for a total of 19 anastomosis with internal mammary artery and 33 venous bypass, was treated with ASA-dipyridamole 300 mg + 400 mg/day. Three and 9 months after surgery, all patients underwent thallium-201 myocardial perfusion imaging, associated with ergometric test. At the first control after 3 months, reversible perfusion defect in one or more myocardial segments was observed in 8 patients of group A and 3 patients of group B (2 A patients and 1 B patient in non revascularized myocardial segments); after 9 months, reversible perfusion defects were observed in 4 A patients and in 4 B patients. After 3 months, non reversible perfusion defect imaging in non infarcted myocardial segments was observed in 2 A patients and in 1 B patient; after 9 months, in 1 patient of both groups. This research shows higher incidence, at first control after 3 months, of ischemic reversible perfusion defects in patients treated with sulodexide, with an evident improvement in some patients recontrolled after 9 months. At the last control after 9 months, the scintigraphic findings showed similar evidence of perfusion defects in both groups treated with sulodexide or ASA-dipyridamole, with concordant angiographic findings (78.6%). Our preliminary results are encouraging and suggest further widespread studies on sulodexide therapy
Sulodexide versus ASA+dipirydamole after coronary bypass graft: assessment with Thallium-201 imaging
Prediction of infarct related coronary artery patency after thrombolytic therapy in acute myocardial infarction; use of ST segment as noninvasive marker
Circadian blood pressure and heart rate changes in patients in a persistent vagetative state after traumatic brain injury
Alteration of autonomic nervous system regulation
is known to be present in the persistent vegetative
state after traumatic brain injury, termed
the dysautonomic syndrome. This study assessed
the circadian blood pressure and heart rate pattern
and variability in the persistent vegetative
state through noninvasive 24-hour ambulatory
blood pressure monitoring. The study was performed
in 20 subjects: 10 patients (six men and
four women; mean age, 29.5±9.9 years; range,
19–39 years) in a vegetative state (mean, 27.3±5.6
days after trauma) and 10 healthy subjects as controls
(six men and four women; mean age, 28±5.7
years; range, 29–37 years). The patients showed
a blood pressure nondipper pattern; 24-hour,
daytime, and nighttime values of blood pressure
and heart rate were significantly higher in patients
than in controls. The day–night difference in
heart rate and blood pressure was also significantly
lower in patients. Finally, SD and variation
coefficients were significantly lower in patients.
The results show changes in the variability and
circadian blood pressure and heart rate patterns
in persistent vegetative state patients with dysautonomic
syndrome, as an expression of the sympathetic–
parasympathetic activity imbalance in
the control of vasomotor tone
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