101,986 research outputs found
Dall'azione al pensiero: il perché di questo libro
No full textEra il 2006 e l’Azienda Usl di Bologna partecipava già da anni al salone fieristico “Sana”. Per la prima volta, però, decise di partecipare nella forma di “Datti una mossa!”, un progetto di comunicazione integrata per promuovere i corretti stili di vita: sana alimentazione, attività fisica e contrasto ai comportamenti a rischio del fumo e dell’alcol. Detto oggi è abbastanza usuale ma allora, per esempio, l’Organizzazione Mondiale della Sanità non ne aveva ancora fatto un basilare comandamento di prevenzione. Il progetto a partire da quell’evento è diventato una vera e propria strategia, una campagna di educazione alla salute permanente con contenuti, eventi ed azioni che si sono protratti fino ad oggi.
“Datti una mossa!” è una campagna fatta di eventi, di incontri con i cittadini dove si esorta a fare e si cerca di fare assieme: correre, camminare, scambiarsi ricette e, naturalmente, riflettere e ragionare. L’idea è quella di “insinuare” un ingrediente fondamentale che leghi tra di loro i corretti stili di vita: lo stare bene insieme. “Datti una Mossa!” nel tempo si è arricchita di esperienze e di saperi, grazie alla rete di referenti e partner che soprattutto negli ultimi tempi hanno stretto tra loro patti e collaborazioni al fine di far crescere un movimento virtuoso
Ogni crisi è un’opportunità: considerazioni finali con l’aiuto di Silvio Garattini
No full textLe conclusioni del volume consentono di riflettere sulle prospettive di azione per il futuro. Nel fare questo ci si avvale anche del contributo di Silvio Garattini, che sottolinea l'importanza di un sistema di sanità pubblica come quello italiano e rilancia sul tema della prevenzione come sfida chiave per il futuro
Fast and Versatile Inverse Hysteresis Model in Quasi-Static Regime: Derivation and Implementation in Simulink and PEEC Frameworks
No full textIn this paper, a fast H(M) magnetostatic hysteresis model is presented, tested, and used in Simulink and partial element equivalent circuit (PEEC) environments. The model is primarily designed to achieve full compatibility with the current 3-D PEEC formalism for nonlinear isotropic magnetic materials, compatibility not met by any direct model. The capabilities of the proposed model are shown in stand-alone configuration and as a core of circuit components within the Simulink environment. Its effectiveness in the 3-D PEEC formulation is then demonstrated
Wideband equivalent-circuit model analysis, realization and time-domain spectroscopy characterization of terahertz periodic metamaterial devices
No full textIn my PhD thesis, I have thoroughly researched THz periodic metamaterial devices by dealing with all the phases of their development: electromagnetic analysis, design, fabrication, characterization, and data post-processing. Initially, for the analysis and design phases, I have adopted an analytical/numerical perspective for the retrieval of the devised circuit topologies. In particular, I have developed and applied equivalent circuit models and parametric macromodels for the physical investigation and optimization of the devices; these methods have been validated by proving their efficiency and effectiveness through the comparison with finite-element method based simulations. Also, they guarantee a wider range of applications in terms of frequency spectra, complexity of geometrical shapes, and material characteristics. For the realization phase, I have used a heuristic procedure of micro-fabrication and after evaluating possible non-idealities, I have made tolerance studies in order to obtain a stable electromagnetic performance. For the characterization of the flexible devices, I have used custom THz-TDS setups for both reflection and transmission-modes; the resulting configurations have proved to be compact and interesting also for further integration in embedded measurement systems. For the data analysis phase, I have post-processed the acquired measurements by implementing retrieval procedures of the constitutive parameters of the samples. Other than topics specifically related to the THz field, I have developed some models of analytical/numerical character for the study of scatterers with discontinuous impedance boundary conditions
An Investigation to Test Spectral Segments as Bacterial Biomarkers
No full textA dictionary-based bacterial genome analysis is performed, through specific k-long factors (called res) and their maximal right elongation along the genome (called spectral segment), in order to find discriminating biomarkers at the genus and species level. The aim is pursued through a k-mer-based approach previously introduced, here applied on genomes of different bacterial taxa. Intervals for values of k are identified to obtain meaningful genomic fragments, whose collection is a suitable representation to compare genomes according to informational indexes and Jaccard’s similarity matrices. Corresponding dictionaries of k-mers are identified to discriminate bacterial genomes at genus and species level. This approach appears competitive in terms of performance (e.g., species discrimination) and size with respect to traditional barcoding methods
Study on the effects of ozone and acid rain on functional parameters of needles of Pinus halepensis Mill.
No full textThe objective of the work is to analyse the direct effects of the single and combined action of ozone and acid rain on Pinus halepensis. The results highlighted that P. halepensis did not show an evident synergism between the two treatments, even though the fluorescence analysis evidenced a different sensitivity of plants to the combined treatment
Morpho-functional characteristics of Quercus ilex L. leaves of different age and their ecophysiological behaviour during different seasons
No full textMorpho-functional characteristics of Quercus ilex L. leaves of different age and their ecophysiological behaviour during different seasons
No full textUse of radish plants protected with EDU to evaluate ozone effects both in natural and in controlled conditions
No full textTargeted therapies in gastrointestinal stromal tumours (GIST): Results and promises
No full textGastrointestinal stromal tumours (GIST) are rare soft tissue sarcomas arising primarily from mesenchymal tissue in the gastrointestinal tract and abdomen. GISTs are diagnosed by strong and diffuse positive immunohistochemical staining of the proto-oncogene c-kit, a type III tyrosine kinase receptor. Approximately 80% of cases have mutated KIT codifying gene, and 5% have mutated platelet-derived growth factor receptor A (PDGFRA). The identification of these mutations as a key factor in the pathogenesis of GIST has substantially altered the diagnosis and treatment of GIST. Imatinib, a molecularly targeted drug that inhibits the kinase activity of KIT and PDGFRs, has been shown to be highly efficacious in patients with advanced GIST. However, early or late tumour resistance to imatinib is an increasing clinical problem. Sunitinib, a multitargeted tyrosine-kinase inhibitor with antiangiogenic activity, is an effective therapeutic option for patients with advanced disease after failure of imatinib treatment
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