1,720,958 research outputs found
Role of diet in absorption and toxicity of oral cadmium- A review of literature
The role of diet or its components in the absorption, distribution and toxicity of cadmium (Cd) has received attention in recent times. Experimental evidence in literature strongly suggests that theabsorption of Cd is dependent on factors such as age, pH, diet and intestinal metallothionein (MT) production. The chemical forms of Cd such as Cd-MT in foods or inorganic Cd administered directly in foods or drinking water have also been considered in literature. The bioavailability or absorption of Cd as Cd-MT in foods has been shown in many reports to have decreased in relation to Cd administered directly as inorganic Cd in drinking water or foods. However, some other studies have reportedcontrary findings. Although research evidence has indicated that the type or components of a diet may also influence the absorption or toxicity of Cd irrespective of the chemical form involved. Diets low in proteins, minerals and certain vitamins have been reported to increase Cd absorption and toxicity. Conversely, diets rich in fibres have the reverse effect. The lack of conclusive information on the availability of Cd in Cd-MT for intestinal uptake in relation to that of ionic Cd is noticeable, and as a result there is a great need for further studies in this area. Also, since humans are usually exposed to Cd-MT in foods and rarely to inorganic Cd, the toxicity of food-incorporated Cd deserves further investigation, in view of the observed differences in tissue accumulation from these forms of Cd
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A comparative study on the biochemical effect of ocular and oral cadmium administration in rabbits
The objective of the present study was to compare the effect of oral and ocular exposure to cadmium for one and three months on some biochemical parameters using rabbits as animal model. The results obtained show that the kidney, femoral muscle, femur and brain of rabbits ocularly exposed to Cd had a significantly higher concentration of Cd relative to that of those administered the metal orally after both periods, except for the liver which was significantly lower. There was a significantly higher membrane lipid peroxidation (LPO) in the kidney of the one and three months exposed rabbits after both oral and ocular exposure to Cd relative to control with a corresponding decrease in the activities of superoxide dismutase (SOD) and catalase (CAT). Irrespective of theroute and time of exposure to the metal, the activity of SOD and CAT were significantly higher in the brain relative to the control, but the level of LPO was not significantly altered. Liver damage induced by oral cadmium after one and three months exposure was clearly shown by the increased activities of plasma hepatic marker enzymes namely, L-aspartate aminotransferase activity (L-AST), L-alanine aminotransferase activity (L-ALT), alkaline phosphatase activity (ALP) along with increased level of LPO indices and a corresponding decrease in the activities of SOD and CAT in the liver. Similarly, liver damage induced by ocular exposure to Cd for one month was manifested as increased plasma L-AST, L-ALT and ALP activities with an increased LPO and a corresponding decrease in the activities of SOD and CAT in the liver. However, the plasma parameters did not significantly change after three months of exposure to ocular Cd, except plasma ALP activity which remained significantly higher. The liver LPO was also not significantly different from the control after three monthsexposure to ocular Cd, although the SOD and CAT activities significantly decreased. Thus the major finding of the present study was that in relation to ocular exposure, oral exposure to Cd was more toxic to the liver at theend of three months of exposure
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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