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Artri King-induced Hypothalamic-pituitary-adrenal Axis Disruption: A Report of 3 Cases.
Full text linkWe present a case series of 3 patients who developed iatrogenic hypothalamic-pituitary-adrenal axis disruption while taking Artri King, an over-the-counter supplement marketed for joint pain that is reported to contain dexamethasone not listed on the supplements label. Patient 1, a 58-year-old woman, presented with persistent hyponatremia, weight gain, proximal muscle weakness, dorsocervical fat pad, and new, red striae on her breast and abdomen in the setting of Artri King use. Her dexamethasone level was elevated (Table 1), confirming the suspicion of dexamethasone content in this supplement. Patient 2, a 55-year old woman, had presented with cushingoid features and a low morning cortisol level (Table 1) in the setting of Artri King use. Patient 3, a 59-year-old man, presented with poorly controlled diabetes in the setting of Artri King use and an elevated serum dexamethasone level. Supplements containing hidden glucocorticoids can cause not only iatrogenic Cushing syndrome, but also adrenal suppression, providing a diagnostic challenge for providers
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
PENGARUH HARGA, PROMOSI PENJUALAN DAN KUALITAS PRODUK TAHU PUTRA MANDIRI JOMBANG TERHADAP KEPUASAN PELANGGAN
Full text linkSkripsi dengan judul “Pengaruh Harga, Promosi Penjualan dan Kualitas Tahu
Putra Mandiri Jombang Terhadap Kepuasan Pelanggan” ini ditulis oleh Findi Artri
Andini, NIM. 126405201054 Program Studi Manajemen Bisnis Syariah, Dosen
Pembimbing Nur Aziz Muslim, M.H.I.
Penelitian ini bertujuan untuk menganalisis pengaruh harga dan promosi
penjualan terhadap kepuasan pelanggan pada industri tahu di Jombang. Metode yang
digunakan adalah kuantitatif dengan pendekatan asosiatif, melibatkan 80 responden yang
dipilih melalui teknik quota sampling. Data primer dikumpulkan melalui kuesioner yang
disebarkan kepada pelanggan Tahu Putra Mandiri. Analisis data dilakukan menggunakan
regresi linier berganda dengan bantuan IBM SPSS 25, yang mencakup uji validitas,
reliabilitas, dan asumsi klasik seperti normalitas dan multikolinieritas. Hasil penelitian
menunjukkan bahwa Harga dan kualitas produk Tahu Putra Mandiri Jombang tidak
berpengaruh signifikan terhadap kepuasan pelanggan, dengan nilai regresi 0,125, t hitung
0,922 (lebih kecil dari t tabel 1,665), dan signifikansi 0,359 (lebih besar dari 0,05).
Demikian juga, kualitas produk tidak berpengaruh signifikan dengan nilai regresi 0,225,
t hitung -1,659 (lebih kecil dari t tabel 1,665), dan signifikansi 0,101 (lebih besar dari
0,05). Sebaliknya, promosi penjualan berpengaruh signifikan terhadap kepuasan
pelanggan, dengan nilai regresi 0,501, t hitung 6,544 (lebih besar dari t tabel 1,665), dan
signifikansi 0,00 (lebih kecil dari 0,05). Secara keseluruhan, harga, promosi, dan kualitas
produk berpengaruh signifikan terhadap kepuasan pelanggan dengan nilai F 27,780 dan
signifikansi 0,000. Nilai R Square sebesar 0,523 menunjukkan bahwa 52,3% pengaruh
terhadap kepuasan pelanggan berasal dari ketiga variabel tersebut, sementara 47,7%
dipengaruhi oleh faktor lain. Kesimpulannya, promosi efektif untuk meningkatkan
kepuasan, sementara harga dan kualitas produk bukan faktor utama untuk loyalitas.
Temuan ini menekankan perlunya strategi harga yang sesuai dengan kualitas produk serta
pemanfaatan media sosial untuk promosi guna meningkatkan kepuasan dan loyalitas
pelanggan. Penelitian ini memberikan wawasan bagi pelaku usaha dalam merumuskan
strategi pemasaran yang lebih efektif untuk mempertahankan pelanggan di tengah
persaingan yang ketat.
Kata Kunci: Harga, Promosi, Kualitas Produk Kepuasan Pelangga
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Endocrinologic Abnormalities Observed Among Total Joint Arthroplasty Patients Using “Artri King” and Related Over-the-Counter Supplements: A Cautionary Tale from a Safety Net Hospital
No full textBackground/Objectives: Artri King is an over-the-counter supplement previously marketed to treat joint pain and arthritis. In 2022, the Food and Drug Administration (FDA) issued a product warning after it discovered Artri King contained hidden ingredients including dexamethasone, diclofenac, and methocarbamol. Given the risk of adrenal insufficiency in the context of long-term dexamethasone use, we sought to report on adverse endocrinologic outcomes observed among patients endorsing the use of these supplements who presented to an orthopedic surgery clinic at a county safety net hospital. Methods: Preoperative patients presenting from November 2023 to June 2024 were screened for supplement use. Data were collected including patient demographics and comorbidities. Serum cortisol, adrenocorticotropic hormone (ACTH), and C-reactive protein (CRP) were obtained to assess adrenal function. Recommendations from Endocrinology regarding perioperative stress dose corticosteroids were also recorded. Standard descriptive statistics were employed to report our results. Results: In total, 13 patients (6 female and 7 male) were identified with a mean age of 62.8 years (range of 47–79 years) and an average BMI of 32.03 kg/m2 (range of 22.93–45.81 kg/m2). The average duration of use was 10.2 months (range of 1–36 months). One patient developed new-onset diabetes mellitus while taking supplements. Nine patients had low cortisol levels (<6.7 mcg/dL), necessitating referral to Endocrinology, and two were found to have concomitantly low ACTH levels (<5 pg/mL). Endocrinology recommended perioperative stress dose corticosteroids for all nine patients with low cortisol. Conclusions: Artri King and similar supplements may lead to severe endocrinological consequences. We recommend routine screening and continued management of patients who endorse supplement use
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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Artri King induced Cushing syndrome in an 82-year-old man
Full text linkAn 82-year-old man with a history of hypertension, thyroid nodule, and parkinsonism on carbidopa/levodopa was referred for a sudden eruption of scattered purpuric macules. He noted fatigue, weakness, ankle swelling, abdominal fullness, headaches, lapses in memory, and dysphasia. On physical examination, he had thin and atrophied upper extremities and central obesity, as well as nonblanching red to purple macules on the lower abdomen and ecchymosis on bilateral arms. The patient denied the use of any corticosteroids. Lab workup showed an abnormally high post-dexamethasone cortisol level, which raised suspicion for Cushing syndrome. Further inquiry into the patient's medication and supplement history revealed that he was consuming Artri King, a supplement marketed for the treatment of joint pain and arthritis. Artri King can lead to numerous dermatological manifestations akin to endogenous Cushing syndrome such as thin skin, easy bruising, and purple striae. This case illustrates the potential risks of over-the-counter dietary supplements, which often circumvent the strict Food and Drug Administration regulations applied to prescription medications, posing significant health hazards to users. There is critical need for transparency and regulation of supplements
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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