1,721,025 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Virulence of MRSA USA300 is enhanced by sub-inhibitory concentration of two different classes of antibiotics.
No full textCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) USA300 is responsible of many kinds of infections of skin and soft-tissue. Antibiotic resistance, biofilm formation and the ability to adhere and invade are virulence factors that contribute to MRSA pathogenesis. In some cases, decreased bioavailability of antibiotics in systemic circulation could result; in these conditions sub-therapeutic levels of the antibiotics may be established, exposing bacteria to sub-inhibitory concentrations. On the basis of several published scientific data it is fair to assume that all these events could induce an increase of bacterial virulence. In the present study, we investigated this process by measuring the effects of low doses of two different classes of antibiotics on some virulence features of MRSA USA300 isolate, like the ability to adhere and invade eukaryotic cells. Results obtained strongly support the importance of the respect of a correct dosage of antibiotic in therapy to escape the insurgence of more virulent phenotypes
Candidosi delle mucose oro-faringee. Aspetti clinici ed epidemiologici in un gruppo di pazienti HIV positivi e con AIDS [Candidiasis of the oropharyngeal mucosa. The clinical and epidemiological aspects in a group of HIV-positive and AIDS patients]
No full textImmune system deficiencies, particularly cell-mediated immunity are the main events of HIV infection. The resulting syndrome is removies: AIDS. This immune deficiency encourages neoplasms such as the Kaposi sarcoma and non Hodgkin lymphoma, above all, it explains the reason why infections supported by opportunist germs, normally not pathogenic for immuno-competent people, are the main reason for morbidity and mortality in this kind of patients. Since among mycotic infections, the main one in these patients is candidiasis, particularly oro-pharyngeal candidiasis, we have carried out a research with the aim of evaluating the main mucosae oris pathologies in HIV and AIDS patients and, among them, the most directly correlated to HIV infection with reference to oro-pharyngeal candidiasis. We have based our research on the analysis of 237 patients case-histories. From January 1993 to December 1994 these patients have been examined at the Odontological Surgery by the "Centro San Luigi" for HIV-correlated pathologies researches and treatments (Istituto Scientifico Ospedale San Raffaele-Milano
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Kupffer cells and T linphocytes form coniugates within the liver of chronic hepatitis C patients that recall dendritic cell-T interactions within the peripheral lymphoid tissue
No full textHepatology 1997, 26 (suppl): 446
Problematiche clinico-diagnostiche e terapeutiche odontoiatriche e stomatologiche nei pazienti HIV positivi e con AIDS [Clinico-diagnostic and odonto-stomatologic therapeutic problems in patients with HIV infection and AIDS]
No full textDuring the last decade, scientific studies and new knowledges concerning HIV infection and AIDS, have constituted one of the main topics for discussion in the fields of biology and medicine. AIDS is a serious disease and it is unfortunately characterized by a very high death rate. In spite of all the efforts deployed by researchers and scientists, there is at present no effective therapy capable of restoring a proper immunological balance in the affected subjects. In the field of odontostomatology all diagnostic, clinical or therapeutic operation in HIV patients, is to be considered as particularly complex and characterized by some degree of real risk. It is therefore necessary to develop a whole set of health-care models which must provide a broad range of different interventions in order to assure a rational and technically profitable service. We point to the various diagnostic, clinical and therapeutic methods and approaches to be recommended in the case of HIV and AIDS patients, and we add some reference to health care activities at the "San Luigi Center" of the Scientific Istitute San Raffaele Hospital in Milan
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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