1,721,058 research outputs found
Morphostructural changes in transferred fasciocutaneous free flaps: a preliminary clinical and immunohistochemical report
No full textSummary Many local factors, yet to be investigated, can promote changes in tissue transferred
by microsurgical technique into the recipient site. Several studies have attempted to
assess the nature of modifications that occur in the vascular network of such a flap after transfer.
Although these investigations have interesting conclusions, the majority of them were
based only on indirect evaluations. The aim of this study was to detect, by histological and statistical
analysis, the morphostructural changes that occurred in fasciocutaneous free flaps
transferred to the cephalic region or to the lower limb. Patients were enrolled in this study
only when neither local inflammatory reactions nor systemic diseases were observed at the
time of biopsy. Six patients consented to undergo biopsy at both the donor and the recipient
area of a previously transferred fasciocutaneous free flap. Three flaps were used for facial reconstruction,
and three others for lower limb reconstruction. Standard staining and immunohistochemical
investigations were performed. The sections were also analysed by specific
software. Statistical analysis of the data was performed using the student’s t-test and Fisher’s
test. In five out of six transferred flaps (83%), there was increased microvascularity compared
to the donor area. It was correlated to the neoangiogenesis in the dermal layer of the flaps. In
five recipient sites there were more new vessels. In particular, a higher score of angiogenesis
was observed both in the cheek (one flap) and in the non weight-bearing area of the foot (two
flaps) (P < 0.001). Some differences in microvascularity between the donor and the recipient
site in the same flap were related to the specific recipient site. This represents the first demonstration
of adaptation of fasciocutaneous free flaps to the recipient area, as well as to their
new function, at both the macroscopic and microscopic level.
a 2008 British Association of Plastic, Reconstructive and Aesthetic Surgeons
Morphostructural changes in transferred fasciocutaneous free flaps: a preliminary clinical and immunohistochemical report
No full textMany local factors, yet to be investigated, can promote changes in tissue transferred by microsurgical technique into the recipient site. Several studies have attempted to assess the nature of modifications that occur in the vascular network of such a flap after transfer. Although these investigations have interesting conclusions, the majority of them were based only on indirect evaluations. The aim of this study was to detect, by histological and statistical analysis, the morphostructural changes that occurred in fasciocutaneous free flaps transferred to the cephalic region or to the lower limb. Patients were enrolled in this study only when neither local inflammatory reactions nor systemic diseases were observed at the time of biopsy. Six patients consented to undergo biopsy at both the donor and the recipient area of a previously transferred fasciocutaneous free flap. Three flaps were used for facial reconstruction, and three others for lower limb reconstruction. Standard staining and immunohistochemical investigations were performed. The sections were also analysed by specific software. Statistical analysis of the data was performed using the student's t-test and Fisher's test. In five out of six transferred flaps (83%), there was increased microvascularity compared to the donor area. It was correlated to the neoangiogenesis in the dermal layer of the flaps. In five recipient sites there were more new vessels. In particular, a higher score of angiogenesis was observed both in the cheek (one flap) and in the non weight-bearing area of the foot (two flaps) (P < 0.001). Some differences in microvascularity between the donor and the recipient site in the same flap were related to the specific recipient site. This represents the first demonstration of adaptation of fasciocutaneous free flaps to the recipient area, as well as to their new function, at both the macroscopic and microscopic level. © 2008 British Association of Plastic, Reconstructive and Aesthetic Surgeons
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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