170,320 research outputs found
Le competenze interculturali nella comunicazione mediale: interpretare per comprendere la Primavera Araba
No full textIl capitolo analizza e descrive alcune nuove competenze per l'educazione degli adulti, in particolare per i giornalisti che necessitano di una formazione specifica al fine di comunicare, con i mass media, le informazioni corrette a favore dell'inclusione. Si riflette soprattutto su un caso specifico: la comunicazione della Primavera Arab
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Ensemble
No full textEnsemble of green/ grey viscose rayon and silk;
A) Jacket with dark grey squares covering same light green/grey color of shirt and pants. Covered with sewn plastic sequins. Long length. Curved seams. 2 enclosed buttons. Open banded collar. Fastened at front with two plastic buttons, which when fastened, are hidden from view by a front placket. Light gray soft collar. Shoulder pads. Fully lined.
Designer's label at inside center back neckline; "Giorgio Armani / Le Collezioni / Made in Italy"
Size label below designer's label; "40 / 6"
B) Pants. Light green/grey rayon. Small waistband with two buttons at zipper to close. Zipper on left side seam. Two pockets at side seams. Pleats in front. Wide legs.
Designer's label at inside center back waistband; "Giorgio Armani / Le Collezioni / Made in Italy"
Size label beside designer's label; "46 / 12"
C) Sheer shirt of rayon. Short sleeves with shoulder pads. 3 iridescent buttons at center back. Round neckline
Epidemiology of motor neuron disease in north-east Veneto region: Venice, Padua, and Belluno Provinces (1972-1981)
No full text
Incidence and risk factors of motor neuron disease in the venice and padua districts of italy, 1972-1979
No full text105 patients with motor neuron disease (MND) from the Provinces of Padua and Venice were evaluated over an 8-year period (1972-1979). Average annual age-adjusted incidence rates rose from 0.49/100,000/year in 1972-1973 to 0.82/100,000/year in 1978-1979. Our epidemiologic survey showed a higher incidence in sparsely populated areas (1.7/100,000/year). A case-control study of 25 patients with MND revealed a statistically significant association with previous fractures (p < 0.01). © 1983 S. Karger AG, Basel
Species identification in surimibased products using Next Generation Sequencing technologies
No full textThe Next Generation Sequencing (NGS) technologies represent the new frontier of the DNA-based analytical methods and they are nowadays largely applied in many research fields. In the food inspection, NGS are especially suitable for species identification in highly processed products composed by a mixture of different species. The lack of the species morphological key features particularly exposes such products at risk for mislabelling and may compromise consumer’s safety if toxic or allergic species are involved. Surimi typically represents a multispecies seafood commodity and it can be described as a myofibrillar protein concentrate, essentially represented by minced fish and cephalopod flesh that has been washed repeatedly with water and strained to remove sarcoplasmatic proteins, lipids and other undesirable components. Following straining, it is usually mixed with cryoprotectants and frozen. Surimi is basically an intermediate product used for the preparation of typical ready-to- eat products such as fish sausages, crabsticks and imitation shrimp products, highly marketed and consumed in almost all countries of the world. In this study, a metabarcoding approach based on the Ion Torrent NGS technologies was applied to detect and identify species within surimi-based products. Sixteen commercial products of both EU and non-EU origin were collected. DNA was extracted from all the products. Libraries were prepared by ligating Ion-compatible adapters to amplicons obtained by amplifying each DNA sample using a 16SrRNA universal primer tested on a wide range of fish and cephalopod species. In particular, the used primer pair was proved in a previous study as able to amplify a fragment of ⁓250-260 (depending on the species) from fish and of 190-200 bp (depending on the species) from cephalopods, both with high inter-species variability. Three equimolar pools of barcoded libraries were prepared: barcoded libraries from samples 1 -6 (Pool 1), samples 7-12 (Pool 2) and samples 13 -16 (Pool 3) were pooled together. Massive DNA clonal parallel amplification and sequencing phases were performed on Ion ChefTM System and Ion PGMTMSystem (Thermo Fisher Scientific), respectively, following the manufacturer protocol. Three Ion 314 v2 BC sequencing chips were loaded (Chip 1 for Pool 1, Chip 2 for Pool 2and Chip 3 for Pool 3). A bioinformatic analysis was performed to evaluate the data quality in term of final number of usable sequences and to obtain the reads taxonomic profile through metabarcoding approach. Overall, 674.983 sequences (78% of total analysed) and 674.826 raw sequences (73% of total analysed) were obtained from Chip 1 and Chip 2, respectively, while Chip 3 was less performant as the 668.081 raw sequences evaluated as usable represented the 58% of all the sequences analysed. Fish DNA was the most represented in all the samples (always greater than 75% and in 75% of the samples greater than 90%); Molluscs DNA was also found in 100% of the samples, in different percentages. In particular, 25% of the samples contained less than 1% of molluscs' DNA, 50% between 1% and 10%, 12.5% between 10% and 20%, and 12.5% more than 20%. DNA from 13 families, 19 genera and 16 species of fish, and from 3 families, 3 genera and 3 species of cephalopods was found. DNA belonging to the Gadidae family was found in 100% of the samples. The percentage was rather high in most of the cases, exceeding 90% in 50% of the samples, ranging from 70 to 90% in 31.2% of the samples and from 40 to 70% in 12.5% of the samples. Gadidae were poorly represented (<2%) only in one Asian sample of non-EU origin. DNA from Gadus genus was found in 100% of the samples, with the species Gadus chalcogrammus identified in 93.75% of the samples, whereas DNA from Gadus morhua was detected in two samples. Also, DNA from Arctogadus genus/Arctogadus glacialis species, Melanogrammus genus/Melanogrammus aeglefinus species and Merlangius genus/Merlangius merlangus species was detected in 6.25%, 43.75% and 6.25% of the samples, respectively. DNA belonging to Merluccidae family was found in 25% of the samples, in variable percentages (from ' 1% to over 36%). and only Merluccius genus/Merluccius merluccius species was present in that samples. 12.3% of DNA from Nemipteridae family/Nemipterus genus (species identification was not reached) was found in one sample. Variable percentage of DNA of species belonging to other ten families was found in some samples. Overall, the most part of the fish species found in the samples were reported in literature as used for surimi production or they were found in studies aimed at identifying species in such type of products. Unconventional species were instead found in three samples of non-EU origin. Regarding molluscs, DNA from Ommastrephidae family/Todarodes genus/Todarodes pacificus species was found in 75% of the samples. DNA belonging to Loliginidae family/Doryteuthis genus/ Doryteuthis opalescens species and Architeuthidae family/Architeuthis genus/Architeuthis dux species was also found in one sample. Differently from fish, the molluscs species found in the analysed samples did not correspond to those listed as the most used in surimi manufacture. Overall, 37.5% of the samples were found as mislabelled. Among them, 25% voluntary declared a species different from those detected in the analysis and 25% (all of non-EU origin) did not report the presence of molluscs on the label, posing a potential health threat for allergic consumers. The presence of vulnerable species was also proved, such in the case of Paretroplus maculatus (Cichlidae family) and Trichopodus leeri (Osphoronemidae family). Although further studies are needed to optimize the analytical protocol and larger number of samples are required, the metabarcoding approach based on the Ion Torrent NGS technologies was proved to be suitable for species identification of processed multispecies seafood products. The great and diversified range of species found in the samples, also including vulnerable ones, as well as the often-undeclared presence of potentially allergic risks, strongly remarks the still too weak control system and poorly eco-friendly management around the global seafood sector, highlighting the necessity to further strengthen the tools aimed at ensuring both consumers and environmental protection
Impact of adrenal steroids on regulation of adipose tissue
No full textCorticosteroids are secreted by the adrenal glands and control the functions of adipose tissue via the activation of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR). In turn, adipocytes release a large variety of adipokines into the bloodstream, regulating the function of several organs and tissues, including the adrenal glands, hereby controlling corticosteroid production. In adipose tissue, the activation of the MR by glucocorticoids (GC) and aldosterone affects important processes such as adipocyte differentiation, oxidative stress, autophagic flux, adipokine expression as well as local production of GC through upregulation of the enzyme 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1). Notably, the proinflammatory responses induced by the MR are counteracted by activation of the GR, whose activity inhibits the expression of inflammatory adipokines. Both GR and MR are deeply involved in adipogenesis and adipose expansion; hence pharmacological blockade of these two receptors has proven effective against adipose tissue dysfunction in experimental models of obesity and metabolic syndrome (MetS), suggesting a potential use for MR and GR antagonists in these clinical settings. Importantly, obesity and Cushing's syndrome (CS) share metabolic similarities and are characterized by high levels of circulating corticosteroids, which in turn are able to deeply affect adipose tissue. In addition, pharmacological approaches aimed at reducing aldosterone and GC levels, by means of the inhibition of CYP11B2 (aldosterone synthase) or 11 beta-HSD1, represent alternative strategies to counter the detrimental effects of excessive levels of corticosteroids, which are often observed in obesity and, more general, in MetS. (C) 2017 American Physiological Society
Linen suit
No full textEnsemble of green and tan linen;
A) Blazer of green check linen. Herring bone weave. Two welted pockets at front. Notched collar. Mid-thigh length. Matching rayon lining. Button hole at lapel. Breast pocket on left hand side still sewn shut from fabrication. One plastic button and buttonhole at center front for closure. Each sleeve has three non-functioning tan plastic buttons. Extra button in plastic bag at right inside lining attached to care information.
Designer's label at inside center back neckline; "Giorgio Armani / Classico / A Milano Borgonuovo 21"
Origin label underneath designer's label; "Made in Italy"
Size label behind designer's label; "46"
Care and content label at inside right side seam.
(b) Straight skirt. Green linen flax. Knee length. Two pockets at sides. Zipper at left hand side seam. Waistband. Two buttons at either side seam along waistband, each fixed with a tab closure. The button closure by the zipper also has stabilizing inner button for the closure. Price tag from Neiman Marcus attached at left hand side seam. Originally priced at 177.
Designer's label at inside center back waistline; "Giorgio Armani / Le Collezioni / Made in Italy"
Size label below designer's label; "14"
Care and content label underneath designer's label.
(c) Tank top. Tan cotton with button and loop fastening at center back. Small tear drop opening below button. Matching nylon lining.
Designer's label at inside back neckline; "Giorgio Armani / A Milano - Borgonuovo 21"
Size label next to designer's label; "I USA F GB D / 48 14 44 18 44"
Origin label below designer's label; "Made in Italy"
Care and content label at inside left side seam
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