5,755 research outputs found

    Shape phase transition in odd nuclei in a multi-j model: The U-B(6)circle times U-F(12) case

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    The phase transition in odd nuclei when the underlying even-even core nuclei experience a transition from spherical to deformed gamma-unstable shapes is investigated. The odd particle is assumed to be moving in the three single-particle orbitals j=1/2,3/2, and 5/2 . At the critical point in the phase transition, an analytic solution to the corresponding Bohr Hamiltonian, called E(5/12), is worked out. Energy spectra and electromagnetic transitions and moments are presented. The same problem is also attacked in the framework of the interacting boson-fermion model (IBFM). Two different Hamiltonians are used. The first one is constructed ad hoc so as to mimic the situation in the E(5/12) model. The second one leads to the occurrence of the O(B)(6)circle times U(F)(12) symmetry when the boson part approaches the O(6) condition. The entire transition line is studied with this Hamiltonian and, in particular, the critical point. Both IBFM calculations at the critical point are consistent with the E(5/12) results

    One-particle spectroscopic intensities as a signature of shape phase transition: The y-unstable case

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    We investigate the evolution of one-particle spectroscopic intensities as a possible signature of shape phase transitions. The study describes the odd systems in terms of the interacting boson-fermion model. We consider the particular case of an odd j=3/2 particle coupled to an even-even boson core that undergoes a phase transition from spherical U(5) to gamma-unstable O(6) situation. At the critical point, our findings are compared with the one-particle spectroscopic intensities that can be obtained within the E(5/4) model proposed by[F. Iachello, Phys. Rev. Lett. 95, 052503 (2005); F. Iachello, in Symmetries and Low-Energy Phase Transitions in Nuclear Structure Physics, edited by G. Lo Bianco (University of Camerino Press, Camerino, Italy, in press)]

    Odd nuclei and shape phase transitions: the role of the unpaired fermion

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    Fortunato, Lorenzo/0000-0003-2137-635X; Arias, Jose M./0000-0001-7363-4328; Alonso, Clara E/0000-0001-9365-4107Shape phase transitions in even and odd systems are reviewed within the frameworks of the Interacting Boson Model(IBM) and the Interacting Boson Fermion Model(IBFM), respectively and compared with geometric models when available. We discuss, in particular, the case of an odd j = 3/2 particle coupled to an even-even boson core that undergoes a transition from the spherical limit U(5) to the gamma-unstable limit O(6). Energy spectrum and electromagnetic transitions, in correspondence of the critical point, display behaviors qualitatively similar to those of the even core and they agree qualitatively with the model based on the E(5/4) boson-fermion symmetry. We describe then the U-BF(5) to SUBF(3) transition when a fermion is allowed to occupy the orbits j = 1/2, 3/2,5/2. The additional particle characterizes the properties at the critical points in finite quantum systems

    The SSC of the Generalised Jahangir’s Graph Jm,k and its Algebraic Characterizations

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    In this article, we present important combinatorial and algebraicproperties of spanning simplicial complex (SSC) of the generalised Jahangir’sgraph Jm,k. We describe the relation to find f−vectors associatedto Δs(Jm,k) and determine the Hilbert series for the SR-ring KΔs(Jm,k).In the end, we present the associated primes of the facet ideal IF(Δs(Jm,k))and the Cohen-Macaulay characterization of the SR-ring of Δs(Jm,k).AMS (MOS) Subject Classification Codes: Primary 13-P10, Secondary 13-F20, 13-C14, 13-H10.Corresponding Author: Agha KashifKey Words: Simplicial Complexes, f-vectors, Spanning Trees, Face Ring, Hilbert Series, CohenMacaulay

    To <i>JM</i> on Its 75th Anniversary

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    This article discusses how Journal of Marketing ( JM) has influenced marketing science and practice by publishing articles on substantive topics relevant to customers, managers, organizations, markets, and society. The journal's 75th anniversary coincides with the 50th anniversary of the Marketing Science Institute (MSI). Frequently, JM and MSI have collaborated to address important substantive marketing issues identified in MSI's Research Priorities. The author highlights seminal articles on brand equity; business-to-business marketing (including sales force management); connecting marketing information, metrics, and strategy; consumer behavior; innovation, new product development. and product management; marketing orientation and capabilities; and market research, methodology and services. She also draws attention to articles that have won the Sheth Foundation/ JM Award and the H. Paul Root Award. The article describes how JM‘s knowledge dissemination is amplified by powerful social network effects. Ideas in JM articles diffuse through the business community, influencing the mind-set of managers worldwide. </jats:p

    Shape phase transitions and critical points

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    We investigate different aspects connected with shape phase transitions in nuclei and the possible occurrence of dynamical symmetries at the critical points. We discuss in particular the behaviour of the neighbour odd nuclei at the vicinity of the critical points in the even nuclei. We consider both the case of the transition from the vibrational behaviour to the gamma-unstable deformation (characterized within the collective Bohr hamiltonian by the E(5) critical point symmetry) and the case of the transition from the vibrational behaviour to the stable axial deformation (characterized by the X(5) symmetry). The odd particle is assumed to be moving in the three single particle orbitals j=1/2,3/2,5/2, a set of orbitals that is known to lead to possible supersymmetric cases. The coupling of the odd particle to the Bohr hamiltonian does lead in fact in the former case at the critical point to the E(5/12) boson-fermion dynamical symmetry. An alternative approach to the two shape transitions is based on the Interacting Boson Fermion Model. In this case suitably parametrized boson-fermion hamiltonians can describe the evolution of the odd system along the shape transitions. At the critical points both energy spectra and electromagnetic transitions were found to display characteristic patterns similar to those displayed by the even nuclei at the corresponding critical point. The behaviour of the odd nuclei can therefore be seen as necessary complementary signatures of the occurrence of the phase transitions.Ministerio de Ciencia e Innovación FIS2008-0418

    JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species

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    \ua9 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Studies showed that JM-20, a benzodiazepine-dihydropyridine hybrid molecule, protects against rotenone and 6-hydroxydopamine neurotoxicity. However, its protective effects against cytotoxicity induced by endogenous neurotoxins involved in Parkinson’s disease (PD) pathogenesis have never been investigated. In this study, we evaluated the ability of JM-20 to inhibit alpha-synuclein (aSyn) aggregation. We also evaluated the interactions of JM-20 with aSyn by molecular docking and molecular dynamics and assessed the protective effect of JM-20 against aminochrome cytotoxicity. We demonstrated that JM-20 induced the formation of heterogeneous amyloid fibrils, which were innocuous to primary cultures of mesencephalic cells. Moreover, JM-20 reduced the average size of aSyn positive inclusions in H4 cells transfected with SynT wild-type and synphilin-1-V5, but not in HEK cells transfected with synphilin-1-GFP. In silico studies showed the interaction between JM-20 and the aSyn-binding site. Additionally, we showed that JM-20 protects SH-SY5Y cells against aminochrome cytotoxicity. These results reinforce the potential of JM-20 as a neuroprotective compound for PD and suggest aSyn as a molecular target for JM-20

    Uterine transplantation: a promising surrogate to surrogacy?

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    Uterine transplantation: a promising surrogate to surrogacy? Grynberg M1, Ayoubi JM, Bulletti C, Frydman R, Fanchin R. Author information Abstract Infertility due to the inability of the uterus to carry a pregnancy ranks among the most unresolved issues in reproductive medicine. It affects millions of women worldwide who have congenital or acquired uterine affections, often requiring hysterectomy, and potentially represents a considerable fraction of the general infertile population. Patients suffering from severe uterine infertility are currently compelled to go through gestational surrogacy or adoption; both approaches, unfortunately, deprive them of the maternal experience of pregnancy and birth. Uterine transplantation represents an outstanding, yet complex, perspective to alleviating definitive uterine infertility. In the past decades, a number of scientific experiments conducted both in animals and women, focusing on uterine transplantation, have led to promising results. Collectively, these findings undoubtedly constitute a sound basis to clinically apply uterine transplantation in the near future. This paper is, however, an overview not only of the extent and limitations of accumulated scientific knowledge on uterine transplantation, but also its ethical implications, in an effort to define the actual place of such an approach among the therapeutic arsenal for alleviating infertility. © 2011 New York Academy of Sciences
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