561 research outputs found
A novel penicillin-binding protein(PBP-D) is involved in amoxicillin resistance in Helicobacter pylori
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Factors Associated to Purchase of Quality-Labelled Beef
Get PDFThe aim of the present study is to identify the factors associated to purchase of quality-labelled beef. For this purpose a total of 364 surveys were carried out on buyers of beef in three Spanish cities. The sample was divided into three groups of buyers according to the beef purchasing habits with a quality label. A logistic regression analysis was used to estimate the differences between groups. The results show the importance of the production region as a quality aspect. Income level, association of quality-labelled beef with “guarantee and tradition” aspects, purchasing frequency, place of purchase, production systems and lifestyles are all variables that enabled us to establish differences between groups.beef quality, quality label, consumer perception, Demand and Price Analysis,
Cryoglobulinemia related to hepatitis C virus infection.
No full textAbstract A causal link among hepatitis C virus (HCV)
infection and essential mixed cryoglobulinemia, cryoglobulinemic
glomerulonephritis, and vasculitis is strongly supported.
HCV triggers autoimmune response in predisposed
individuals that manifests as organ-specific and non–
organ-specific autoantibodies and as polyclonal/monoclonal
rheumatoid factor, which has a central role in causing damaging
cryoglobulin and immune complex tissue levels. Immunologic
events are mainly induced by HCV infection
persistence, with excessive immune stimulation. Humoral
immune dysfunction leads to autoantibodies and rheumatoid
factor production with cryoglobulinemia, glomerulonephritis,
vasculitis, neuropathy, and probably thyroiditis, and
arthritis in rare cases. Cellular immune dysfunction leads
to lymphocytic infiltration, proliferation, and cytokine production.
Pegylated (or not) interferon-alpha in combination
with ribavirin appears to be the treatment of choice for patients
with symptomatic essential mixed cryoglobulinemia with or without glomerulonephritis. Novel treatment with
rituximab is promising
Helicobacter pylori infection in shepherds, sheep and sheep-dogs
No full textObjectives: Previous studies demonstrated a high prevalence of Helicobacter pylori infection
among shepherds, sheep, sheep raw milk and children having contact with sheep, suggesting a model of transmission
of infection at elevated frequency. The aim of this study was to examine whether H. pylori infection might
be present in sheep-dogs.
Material and Methods: Stool, serum, and wool were collected from sheep and sheep-dogs belonging to different
flocks chosen because the shepherds had documented (13C-UBT) H. pylori infection. H. pylori status in
the animals was evaluated using a homemade anti-H. pylori IgG enzyme-linked immunosorbent assay (ELISA)
for sheep and sheep-dogs. Stool samples from sheep and sheep-dogs were also analyzed using the stool antigen
test (HpSA) developed for humans. Results were expressed as optical density (OD450). PCR amplification was
performed using primers specific for H. pylori [cagA, vacA (s and m region), iceA, babA2] as well as primers
specific for Helicobacter species (16S rRNA) from the DNA extracted from sheep wool wash surrounding the
mammalian glands.
Results: 58 animals were studied (44 sheep, 8 lambs and 6 sheep-dogs). The H. pylori antigen test was positive in
82% (36/44) and in 100% of sheep and sheep-dogs stool samples, respectively. Lamb stool samples were weakly
positive. High anti H. pylori IgG serum levels were detected in all 6 sheep-dogs and in 42 of 44 sheep. Genomic
H. pylori and Helicobacter species DNA was not detected from any of the sheep wool samples collected.
Conclusions: Although cross-reactivity cannot be excluded, the presence of the H. pylori antigen in stools obtained
from sheep and from sheep-dogs, and the strong positivity for anti H. pylori IgG in both coupled with the
ability to isolate H. pylori from sheep milk and stomachs, suggest that interaction between species may enhance
the spread of bacteria in heavily contaminated settings
A meta-analytical approach to understanding the effect of metronidazole resistance on outcome of H-pylori therapy.
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Detection of genomic Helicobacter pylori DNA in the blood of patients positive for the infection.
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