1,721,077 research outputs found

    Studio della relazione tra alimenti senza glutine e microbiota nei soggetti celiaci

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    La malattia celiaca (CeD) è una patologia autoimmune cronica scatenata dall'ingestione di glutine, che porta a infiammazione e danni alla mucosa intestinale. La gestione della CeD si basa su una dieta rigorosa priva di glutine (gluten-free, GFD), che spesso include alimenti processati. Tuttavia, gli studi recenti suggeriscono che l'inclusione di sottoprodotti alimentari ricchi di componenti bioattivi, come la buccia d'arancia e le foglie di carciofo, potrebbe arricchire tali diete, fornendo ulteriori benefici per la salute. Questi sottoprodotti, spesso scartati, sono ricchi di composti bioattivi con proprietà antiossidanti, antimicrobiche e antitumorali, che possono contribuire a migliorare la salute intestinale e generale dei pazienti celiaci. I polifenoli e i flavonoidi presenti nelle bucce d'arancia e nelle foglie di carciofo svolgono un ruolo cruciale nella riduzione dello stress ossidativo, nel miglioramento della risposta immunitaria e nella protezione delle cellule dai danni provocati dai radicali liberi. Inoltre, la loro azione antimicrobica può contribuire al mantenimento di un equilibrio sano del microbiota intestinale, riducendo il rischio di infezioni e infiammazioni, mentre le proprietà antitumorali potrebbero fornire una protezione contro lo sviluppo di malattie croniche associate. L'integrazione di questi sottoprodotti alimentari nella dieta gluten-free potrebbe quindi rappresentare una strategia innovativa per migliorare la qualità nutrizionale e il benessere complessivo dei pazienti celiaci, andando oltre la semplice eliminazione del glutine.Celiac disease (CeD) is a chronic autoimmune condition triggered by the ingestion of gluten, leading to inflammation and damage to the intestinal mucosa. The management of CeD relies on a strict gluten-free diet (GFD), which often includes processed foods. However, recent studies suggest that the inclusion of food by-products rich in bioactive components, such as orange peel and artichoke leaves, could enrich these diets, providing additional health benefits. These by-products, often discarded, are rich in bioactive compounds with antioxidant, antimicrobial, and antitumor properties, which can contribute to improving the intestinal and overall health of celiac patients. The polyphenols and flavonoids found in orange peels and artichoke leaves play a crucial role in reducing oxidative stress, enhancing immune response, and protecting cells from damage caused by free radicals. Additionally, their antimicrobial action can help maintain a healthy balance of gut microbiota, reducing the risk of infections and inflammation, while their antitumor properties could provide protection against the development of associated chronic diseases. The integration of these food by-products into the gluten-free diet could, therefore, represent an innovative strategy to improve the nutritional quality and overall well-being of celiac patients, going beyond the mere elimination of gluten

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    Tsunami Modeling and Satellite-Based Emergency Mapping: Workflow Integration Opportunities

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    Satellite-based Emergency Mapping (SEM) mechanisms provide information for emergency response in relation to dierent types of disasters, including tsunamis, based on the analysis of satellite imagery acquired in the aftermath of an event. One of the main critical aspects of a SEM service is the timeliness in providing relevant information in the hours following the event. The availability of a relevant post-event image is crucial; therefore, satellite sensors need to be programmed as soon as possible. The integration of a tsunami alerting system, like the one oered by the Global Disaster Alert and Coordination System (GDACS), can be highly beneficial in a SEM mechanism for streamlining and accelerating the satellite programming task and for generating first damage estimates. The GDACS tsunami model is validated using tidal gauge data and a post-event field survey. Tsunami model outputs are then exploited to automatically identify areas of interest to be used for immediate satellite acquisition triggering. Three alternative operational integration approaches are proposed, described and discussed, taking as use case the tsunami that struck the central Chilean coast after the 8.3 magnitude earthquake on 16 September 2015

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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