1,721,052 research outputs found
Clearance of Salmonella typhi studied experimentally on the isolated and perfused rat liver: preliminary results
Effect of diphtheria toxin on isolated perfused liver in vitro: preliminary observations
The effect of diphtheria toxin on liver cell cytoplasm and mitochondria was evaluated by studying the release of malic dehydrogenase (MDH), glutamic pyruvic transaminase (GTP), and glutamic dehydrogenase (GLDH) enzyme activities from the isolated rat or guinea pig liver treated with toxin. Perfusions were prolonged for 6 hours after the addition of the toxin to the medium: 500 guinea pig MLD for rat liver perfusion, 1 guinea pig MLD for guinea pig liver perfusion. For both animal species MDH, GPT and GLDH values in perfusate samples of toxin experiments did not differ significantly from their control experiments. (25 references.
Clearance of viable Salmonella strains by the isolated, perfused rat liver: a study of serum and cellular factors involved and of the effect of treatments with carbon tetrachloride or Salmonella enteritidis lipopolysaccharide
Hepatic clearance of Salmonella paratyphi B studied experimentally on the isolated and perfused rat liver
Rat serum bactericidal activity on S. aureus grown in presence of cefamandole and gentamicin at sub-MICs concentrations
Visceral leishmaniasis during pregnancy treated with meglumine antimoniate.
Data on the efficacy and safety of pentavalent antimony in the treatment of
visceral leishmaniasis during pregnancy are scanty. A case of visceral
leishmaniasis in a 39-year-old woman in the second trimester of pregnancy is
reported here. The patient was hospitalized in poor condition with high fever and
pancytopenia which had lasted for 6 weeks. A bone marrow aspirate revealed
numerous amastigotes and serodiagnosis for Leishmania was positive at a high
titer. The patient was successfully treated with meglumine antimoniate at a daily
dose of 850 mg of antimony for 20 days. She delivered at term a healthy female
baby who remains in good condition at 18 months of age. Thus a dose of 850 mg of
antimony, which is lower than that presently recommended, seems to be effective
and non toxic to the fetus when administered at the second trimester of
pregnancy
Visceral leishmaniasis during pregnancy treated with meglumine antimoniate
Data on the efficacy and safety of pentavalent antimony in the treatment of visceral leishmaniasis during pregnancy are scanty. A case of visceral leishmaniasis in a 39-year-old woman in the second trimester of pregnancy is reported here. The patient was hospitalized in poor condition with high fever and pancytopenia which had lasted for 6 weeks. A bone marrow aspirate revealed numerous amastigotes and serodiagnosis for Leishmania was positive at a high titer. The patient was successfully treated with meglumine anti-moniate at a daily dose of 850 mg of antimony for 20 days. She delivered at term a healthy female baby who remains in good condition at 18 months of age. Thus a dose of 850 mg of antimony, which is lower than that presently recommended, seems to be effective and non toxic to the fetus when administered at the second trimester of pregnancy. © 1995 MMV Medizin Verlag GmbH
Sensitivity of bacteria exposed to subinhibitory concentration of antibiotics, serum and liver macrophages activity of rats
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