1,720,995 research outputs found
Baldoni Franco, Giannotti Michele, Facondini Elisa, Cena Loredana, Dilorenzo Margherita, Ancora Gina, Chirico Gaetano L’influenza del padre sullo sviluppo psicomotorio del bambino nato pretermine
No full textLa nascita prematura di un bambino rappresenta un evento pericoloso,
stressante e potenzialmente traumatico non solo per il neonato, ma per tutta la famiglia. Nonostante il progresso scientifico abbia comportato una riduzione significativa dei tassi di mortalità, la prematurità rimane infatti la seconda causa di morte nei bambini al di sotto dei 5 anni ed è associata al
rischio di ulteriori complicazioni neonatali e future disabilità del bambino. La ricerca, però, ha evidenziato come gli esiti evolutivi dei bambini prematuri dipendano non solo dai fattori somatici e medici, ma anche da quelli ambientali, in particolare dalla qualità delle
relazioni con i genitori. Il ricovero e la permanenza nel reparto di terapia intensiva neonatale (TIN) mettono a dura prova l’equilibrio psicologico e le relazioni dell’intera famiglia, influenzando la salute mentale dei genitori, con conseguenze significative sul loro modo di relazionarsi come coppia e di accudire il piccolo. Nel caso specifico di una nascita prematura, il padre viene coinvolto
attivamente sin dalle primissime fasi ed è chiamato a svolgere diversi compiti (interfacciarsi con i medici, prendere decisioni, comunicare con i familiari, avere i primi contatti con il bambino), dato che la madre è spesso
costretta a letto per riprendersi dal parto .
Studi recenti hanno evidenziato nei padri di bambini pretermine la
frequente manifestazione di alterazioni emotive che comportano effetti diretti e indiretti sulla qualità dell’interazione diadica. Alcuni dati clinici ed
empirici hanno rivelato che i padri si sentono spesso alienati, disorientati
e impreparati a gestire le difficoltà connesse alla prematurità, esprimendo
un forte bisogno di condividere i propri vissuti .
Gli stati emotivi dei genitori durante il periodo perinatale, però, si
influenzino reciprocamente e questo aumenta il rischio di sviluppare un
disturbo psicologico quando il partner riporta una sintomatologia clinicamente significativa .Come nel caso delle madri, infatti, anche i padri possono presentare un rischio maggiore di disturbi affettivi depressivi e ansiosi, e il rischio aumenta nel caso di una nascita pretermine
Quando l’acqua cheta... rode i timpani [When the still waters... gnaws the eardrums]
No full textL’otomastoidite va tenuta in considerazione nella diagnosi differenziale della paralisi del nervo facciale, che ne costituisce una rara complicanza, la cui incidenza stimata è dello 0,005% e la cui prognosi è eccellente con atteggiamento terapeutico conservativo
Dexmedetomidine as a Promising Neuroprotective Sedoanalgesic in Neonatal Therapeutic Hypothermia: A Systematic Review and Meta-Analysis
Get PDFBackground: Hypoxic-ischemic encephalopathy (HIE) is a leading cause of neonatal mortality and neurodevelopmental disabilities. Therapeutic hypothermia (TH) is the standard of care, but optimized sedoanalgesic strategies remain critical. Dexmedetomidine shows promise as an alternative to traditional sedatives, but its role in this context remains systematically underexplored. Objective: This meta-analysis evaluates the safety and efficacy of dexmedetomidine in neonates undergoing TH for HIE. Methods: A systematic search of Medline, Scopus, EMBASE, WOS, ClinicalTrials, and Cochrane Library identified studies published from January 2014 to October 2024. Studies focusing on dexmedetomidine in neonatal TH with relevant outcomes were included. Selection followed PRISMA guidelines, with independent quality assessments. The protocol was registered in PROSPERO (CRD42024605817). Results are presented as meta-analyses or evidence-based discussions when pooling was unfeasible. Results: Seven studies involving 609 neonates were included: four cohort studies (n = 486) and three case series (n = 123). Dexmedetomidine provided comparable sedation to traditional agents (MD = -0.01 [-0.68 - 0.66], p = 0.99) and significantly reduced seizure risk (OR 0.31 [0.10 - 0.98], p < 0.05) with a non-inferior safety profile. Trends suggested shorter duration of mechanical ventilation and time to full enteral feeding. Substantial heterogeneity in dosing protocols highlights the need for standardization. Conclusions: Dexmedetomidine appears to be a safe and promising sedative in neonatal TH for HIE, with potential neuroprotective, respiratory, and gastrointestinal benefits. Despite limited evidence and the absence of randomized clinical trials, its non-inferior efficacy and safety warrant further exploration and urges the development of standardized dosing protocols
Amplitude-integrated EEG recorded at 32 weeks postconceptional age. Correlation with MRI at term
No full textObjective The study aims to establish the role of late aEEG (scored by Burdjalov) in predicting brain maturation as well as abnormalities evaluated at term equivalent age (TEA) by brain MRI. Methods 91 infants born before 30 wks gestation underwent an aEEG monitoring at 32 wks postconceptional age (PCA). aEEG, was correlated with TEA MRI, scored by Kidokoro. Results A significant correlation between the aEEG score and the MRI scores was found. The same results were obtained for the aEEG continuity score; cyclicity and bandwidth scores were associated with grey matter and cerebellar MRI items. Moreover, a correlation between aEEG and cEEG recorded both at 32 and 40 wks PCA, was found. Conclusions aEEG monitoring can be predictive of MRI findings at TEA, suggesting that it could be implemented as a useful tool to support ultrasound to help identify neonates who will benefit from early intervention services
Parechovirus infection causing sepsis-like illness in newborns: a NICU approach
No full textHuman parechovirus (HpeV) is an important emerging infection in young infants, able to cause sepsis-like disease and meningoencephalitis, especially in newborns. Among the 19 identified genotypes, HPeV1, 3 and 6 are the most common types involved in human infections; HPeV3 is the type mainly responsible for neonatal infections and for infections involving the central nervous system. Signs and symptoms overlap with those of a bacterial infection and patients are usually treated with broad spectrum antibiotics. In the majority of cases lumbar puncture shows absence of pleocytosis, even in the presence of signs of meningitis. In these cases, cerebrospinal fluid cultures are negative for bacteria but, in the absence of diagnosis of viral infection, a full and unnecessary antibiotic cycle is often continued. Moreover, high sensitivity neuroimaging, i.e., magnetic resonance, and follow-up are often missed, thus resulting in substandard care. Availability of a real time PCR assay for HPeV RNA allows rapid and sensitive diagnosis as long as the disease is suspected. In this case study, we present cases of HPeV infections in newborns requiring neonatal intensive care admission, discuss their optimal management, and highlight the most relevant findings in the literature
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
