63 research outputs found
STUDIO OSSERVAZIONALE DELLE LESIONI SOPRARENALI DIAGNOSTICATE IN ETA PRE O PERINATALE: RISULTATI PRELIMINARI
No full textProsperi Fagnani Jus canonicum, sive, Commentaria absolutissima in V. libros decretales : cum indice copiosissimo rerum ac verborum alphabetica serie digesto, & iuxta materiarum varietatem distincto : tomus primus[-quintus] complectens primam[-secundam] partem primi libri Decretalium.
No full textPaging, v. 1, pt. 1: [12], 284 p. -- v. 1, pt. 2: [4], 616 [i.e. 630] p. -- v. 2: [4], 264 p. -- v. 3, pt. 1: [4], 406 p. -- v. 3, pt. 2: [4], 438 [i.e. 440] p. -- v. 4: [4], 110 [i.e. 116] p. -- v. 5, pt. 1: [4], 111-350 p. -- v. 5, pt 2: [4], 216 p. -- Index: [344] p.Two different engraved t.p. vignettes appear respectively in vols. published by Haeredes Widenfelt and by Friessem, the former signed "St." Head- and tail-pieces, initials.Vols. 1, 3 & 5 in two pts. Vols. 2-5, the second pts., and index have special added t.p.'s. Starting with pt. 2 of v. 3, publisher is Johann Wilhelm Friessem Jr., save for index, again published by Haeredes Widenfelt.VD17Mode of access: Internet.Ownership inscriptions of Christophor Ferdinand von Nagell zu Ittlingen, abbot of Kloster Varlar, 1699. Ownership inscriptions of J. Wiesert, pastor in Velen, 1816. Signature of H.W. Westhott. Property stamps of Sankt Georgen, Frankfurt/M, with "I.H.S."Getty copy bound in 4 v. in vellum. Lapped foredges. Author & title written at head of spine, printed label of St. Georgen with shelfmark at foot. Edges red
PRE/PERINATALLY DIAGNOSED SUPRARENAL LESIONS: PRELIMINARY DATA FROM AN OBSERVATIONAL ULTICENTRIC STUDY.
No full textManagement and follow-up of urothelial neoplasms of the bladder in children: A report from the TREP project.
No full textBACKGROUND: Urothelial neoplasms of the bladder (UNB) are rare in patients under 20 years of age, and even rarer in the first decade of life. The present series was investigated to provide recommendations on patient management in terms of therapeutic strategy and follow-up.
PROCEDURE: This is a retrospective analysis on 12 patients with UNB under 18 years of age. Data were extracted from the national database of the TREP (Tumori Rari in Età Pediatrica) Project.
RESULTS: Ten of the 12 patients presented with a single episode of hematuria, while the discovery of the lesion was incidental in two. Eleven of the 12 lesions were G1 and one was G2/G3; none of the lesions invaded the lamina propria. All lesions were removed completely by transurethral resection. No further treatment was administered in nine children but three received a single dose of intravesical chemotherapy (epirubicin in 2, mitomycin in 1). Only one patient experienced a recurrence and all patients are alive in complete remission with a median follow-up of 30 months (range 4-112). Follow-up investigations varied at the different centers and included abdominal ultrasound in nine patients, cystoscopy in seven, and additional radiological investigations in a few cases.
CONCLUSIONS: UNB in children seems to be a low-grade, scarcely aggressive disease with an excellent prognosis. The role of intravesical chemotherapy is debatable. Follow-up can be based on ultrasound. The adoption of shared recommendations should enable unnecessary treatment and invasive investigations to be avoided. Pediatr Blood Cancer © 2014 Wiley Periodicals, Inc
"The nights here are wonderful; and I am never weary of observing the loveliness of the skies". Tourists with Disabilities in Italy in the Nineteenth and Early Twentieth Centuries
No full text«The nights here are wonderful; and I am never weary of observing the loveliness of the skies». Tourists with disabilities in Italy in the nineteenth and early twentieth centuries
No full textManagement and follow-up of urothelial neoplasms of the bladder in children: a report from the TREP project
No full textBACKGROUND:
Urothelial neoplasms of the bladder (UNB) are rare in patients under 20 years of age, and even rarer in the first decade of life. The present series was investigated to provide recommendations on patient management in terms of therapeutic strategy and follow-up.
PROCEDURE:
This is a retrospective analysis on 12 patients with UNB under 18 years of age. Data were extracted from the national database of the TREP (Tumori Rari in Età Pediatrica) Project.
RESULTS:
Ten of the 12 patients presented with a single episode of hematuria, while the discovery of the lesion was incidental in two. Eleven of the 12 lesions were G1 and one was G2/G3; none of the lesions invaded the lamina propria. All lesions were removed completely by transurethral resection. No further treatment was administered in nine children but three received a single dose of intravesical chemotherapy (epirubicin in 2, mitomycin in 1). Only one patient experienced a recurrence and all patients are alive in complete remission with a median follow-up of 30 months (range 4-112). Follow-up investigations varied at the different centers and included abdominal ultrasound in nine patients, cystoscopy in seven, and additional radiological investigations in a few cases.
CONCLUSIONS:
UNB in children seems to be a low-grade, scarcely aggressive disease with an excellent prognosis. The role of intravesical chemotherapy is debatable. Follow-up can be based on ultrasound. The adoption of shared recommendations should enable unnecessary treatment and invasive investigations to be avoided
Appendiceal Neuroendocrine Tumors (Carcinoid of the Appendix) in Childhood: A Clinical Report From the Italian Trep Project.
No full textBACKGROUND:: Neuroendocrine tumors (NETs) of the appendix are slow-growing tumors and, although rare, they are the most common G-I epithelial tumors in childhood and adolescence. The treatment and the follow-up screenings have not been standardized. Above all, though tumor size is considered the main prognostic variable to define the aggressiveness of approach, it remains to be established a precise cut-off.
METHODS:: 113 patients under 18 years of age with a diagnosis of appendiceal NETs were registered as of 1 January 2000 until 30 May 2013 within the TREP Project (Rare Tumors in Pediatric Age), an Italian multi-institutional network dedicated to very rare tumors in children and adolescents. The recommendations of the TREP study included imaging and laboratory investigations. The treatment after appendectomy was decided on the basis of histology, tumor size and imaging: primary re-excision (PRE) was not recommended in completely excised tumors, regardless of tumor size and invasiveness.
RESULTS:: 113/113 had a diagnosis of well differentiated NETs: in 108/113 the tumor was smaller than 2 cm and in 5 larger than 2. Excision margins were free in 111/113 patients. In 3/113 a PRE was performed: in 1 residual tumor was detected. 113/113 patients are alive in complete remission (median follow-up of 41 months).
CONCLUSIONS:: Reported data and our experience showed that no relapse or death occurred in children and adolescents affected by appendiceal NETs. Appendectomy alone should be considered curative for most patients and a more aggressive surgical approach is deserved in those cases with incompletely excised tumors
Des assistantes maternelles mieux formées et plus qualifiées. Les parents consentiraient-ils à augmenter la rémunération ?
No full textNational audienceLe métier d'assistant maternel (AM) a récemment bénéficié de mesures qui se sont traduites par une relative amélioration de leur statut et conditions de travail. Dans un contexte de forte demande pour ce mode d'accueil, afin de valoriser ce métier et de le rendre plus attractif, l'enjeu de l'approfondissement de la formation a aussi été mis en exergue par les pouvoirs publics. Cependant, cette préoccupation ne peut avoir de sens que si la perspective d'une augmentation de la rémunération existe. Or, dans un contexte de limitation, voire de restrictions des dépenses publiques, cette augmentation n'est envisageable que si les parents consentent à payer davantage. Des entretiens avec des AM témoignent de leur scepticisme à cet égard. Une enquête statistique, menée dans le département du Val-de- Marne auprès de parents qui recourent à ce mode d'accueil, montre qu'un tiers seulement d'entre eux seraient disposés à augmenter la rémunération pour bénéficier des services d'une AM plus qualifiée. Le niveau de revenus des parents, la durée de travail hebdomadaire de la mère et l'opinion des parents sur le métier d'AM sont les facteurs qui différencient les parents en la matière
Opinion fluctuations and disagreement in social networks
No full textWe study a tractable opinion dynamics model that generates long-run disagreements and persistent opinion fluctuations. Our model involves an inhomogeneous stochastic gossip process of continuous opinion dynamics in a society consisting of two types of agents: regular agents, who update their beliefs according to information that they receive from their social neighbors; and stubborn agents, who never update their opinions and might represent leaders, political parties or media sources attempting to influence the beliefs in the rest of the society. When the society contains stubborn agents with different opinions, the belief dynamics never lead to a consensus (among the regular agents). Instead, beliefs in the society fail to converge almost surely, the belief profile keeps on fluctuating in an ergodic fashion, and it converges in law to a non-degenerate random vector. The structure of the graph describing the social network and the location of the stubborn agents within it shape the opinion dynamics. The expected belief vector is proved to evolve according to an ordinary differential equation coinciding with the Kolmogorov backward equation of a continuous-time Markov chain on the graph with absorbing states corresponding to the stubborn agents, and hence to converge to a harmonic vector, with every regular agent's value being the weighted average of its neighbors' values, and boundary conditions corresponding to the stubborn agents' beliefs. Expected cross-products of the agents' beliefs allow for a similar characterization in terms of coupled Markov chains on the graph describing the social network. We prove that, in large-scale societies which are highly fluid, meaning that the product of the mixing time of the Markov chain on the graph describing the social network and the relative size of the linkages to stubborn agents vanishes as the population size grows large, a condition of homogeneous influence emerges, whereby the stationary beliefs' marginal distributions of most of the regular agents have approximately equal first and second moment
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