177,697 research outputs found
O percurso ideológico de D. António Alves Martins: do Cabralismo à Janeirinha (1842-1868)
No full textD. António Alves Martins foi um bispo e político português do século XIX. Ao mesmo tempo que progredia na vida eclesiástica (frade da Ordem Terceira em 1825, ascendeu a Bispo de Viseu em 1862), Alves Martins empenhou-se na carreira política. Deputado várias vezes entre 1842 e 1864, foi Par entre 1864 e 1882 e Ministro do Reino três vezes entre 1868 e 1871. Fundou três partidos: o Partido de Viseu (1865), de carácter local; o Partido Reformista (1870), que agregava os apoiantes do seu governo; e o Partido Progressista (1876), uma fusão do anterior com o Partido Histórico. Esta dissertação tem como fim definir a ideologia política de Alves Martins, tendo em conta a sua leitura da realidade e o seu programa para o País, no contexto do século XIX português. Tendo apoiado a Carta Constitucional de 1826 durante muitos anos, defendeu a sua revisão para adaptação às mudanças sociais que entretanto ocorriam. Essa orientação explica a sua oposição ao radicalismo do Partido Cabralista a partir de 1842. Em 1851, aderiu à Regeneração e nos anos seguintes procurou proteger esse acordo entre partidos, inclusivamente pela sua actualização, dado que as suas ideias, moderadas mas progressistas, contemplavam a evolução social. Em economia, defendia amplas liberdades individuais e, dada a escassez de dinheiros públicos, investimentos públicos cuidadosamente escolhidos em finanças. Defendeu a separação de jurisdições da Igreja e do Estado e opôs-se ao poder temporal do Papa, o que, dada a sua personalidade algo áspera, lhe valeu a imagem de revolucionário, a admiração de progressistas e republicanos e a aversão de sectores conservadores e reaccionários. Porém, permaneceu um católico ortodoxo e respeitou os dogmas e o poder espiritual da Igreja, tendo defendido o regresso das Ordens Religiosas a Portugal. A crise financeira de 1868 colocou-o no governo, mas o seu programa (e o do seu Partido Reformista), conquanto progressista e ambicioso, ficou limitado às medidas urgentesD. António Alves Martins was a portuguese bishop and politician of the XIX century. As he progressed in his ecclesiastical vocation (he was friar of the Ordem Terceira in 1825 and ended as Bishop of Viseu), he engaged in a political career. Several times a member of the House of Deputies, between 1842-1864, he was a Peer between 1864-1882 and Realm Minister three times between 1868-1871. He founded three parties: the Partido de Viseu (1865), a local party; the Partido Reformista (1870), which joined together the supporters of his government; and the Partido Progressista (1876), which merged the latter with the Partido Histórico. This dissertation aims at defining the political ideology of Alves Martins in the context of nineteenth century Portugal, bearing in mind his interpretation of reality and his programme for the country. Having supported the 1826 Constitutional Charter for several years, he advocated a constitutional reform to meet the social changes that occurred in the meantime, which explains his opposition to the radicalism of the Partido Cabralista from 1842. In 1851, he joined the Regeneração and for the next years tried to shield the agreement established between the parties at the time, including by bringing it up to date, as his ideas, which were moderate but progressive, bore in mind social evolution. He favoured wide economic freedom for individuals and carefully chosen public expenditure, given the lack of public funding. He advocated jurisdictional separation between the Church and the State and opposed the temporal power of the Pope, which, given his somewhat harsh personality, earned him a revolutionary image, the praisal by progressive and republican personalities and rejection of conservative and reactionary sectors. He remained an orthodox catholic nonetheless and complied with the dogmas and the spiritual power of the Church, having supported the return of the religious orders to Portugal. The 1868 finantial crisis led him to the government, but his programme (and also his party’s), although progressive and ambitious, was limited to urgent measures
Medidas de produtividade: dilemas da agricultura familiar.
No full textTambém publicado em: VILELA, D.; BRESSAN, M.; FERNANDES, E. N.; ZOCCAL, R.; MARTINS, M. C.; NOGUEIRA NETTO, V. (Ed.). Gestão ambiental e políticas para o agronegócio do leite. Juiz de Fora : Embrapa Gado de Leite, 2003. 314 p. Trabalhos apresentados no 3 Congresso Internacional do Leite, Araxá, 2003. Na publicação: Eliseu Alves
Ceradocus Alves, Johnsson & Senna, 2019, sp. nov.
No full textCeradocus Costa, 1853 Genus composition. Ceradocus (Ceradocus) breweri (Kunkel, 1910); C. (C.) colei Kunkel, 1910; C. (C.) diversimanus (Miers, 1884); C. (C.) laevis Oleröd, 1970; C. (C.) natalensis Griffiths, 1974; C. (C.) orchestiipes Costa, 1853; C. (C.) parkeri Kunkel, 1910; C. (C.) shoemakeri Fox, 1973; C. (C.) spinicauda (Holmes, 1908); C. (C.) woorree Berents, 1983; C. (Denticeradocus) adangensis Wongkamhaeng & Boonyanusith, 2016; C. (D.) andamanensis Wongkamhaeng, Coleman & Pholpunthin, 2013; C. (D.) baudini Hughes, 2016; C. (D.) capensis Sheard, 1939; C. (D.) chevreuxi, Sheard, 1939; C. (D.) chiltoni Sheard, 1939; C. (D.) alama Myers & Nithyanandan, 2016; C. (D.) circe Lowry & Springthorpe, 2005; C. (D.) cotonensis Appadoo & Myers, 2006; C. (D.) crenatipalma Ledoyer, 1979; C. (D.) dooliba J.L. Barnard, 1972; C. (D.) greeni Appadoo & Myers, 2005; C. (D.) haumuri J.L. Barnard, 1972; C. (D.) hawaiensis J.L. Barnard, 1955; C. (D.) isimangaliso Milne & Griffiths, 2013; C. (D.) inermis Hirayama, 1986; C. (D.) koreanus Kim & Kim, 1989; C. (D.) mahafalensis Ledoyer, 1979; C. (D.) mizani Lim, Azman & Othman, 2010; C. (D.) nanhaiensis Ren, 2012; C. (D.) nghisonensis Thanh & Anh, 2011; C. (D.) oliveri Appadoo & Myers, 2006; C. (D.) oxyodus Berents, 1983; C. (D.) paucidentatus J.L. Barnard, 1952; C. (D.) ramsayi (Haswell, 1879); C. (D.) rubromaculatus (Stimpson, 1856); C. (D.) sellickensis Sheard, 1939; C. (D.) serratus (Bate, 1862); C. (D.) setosus Thanh & Anh, 2011; C. (D.) shoalsi Appadoo & Myers, 2006; C. (D.) sheardi Shoemaker, 1948; C. (D.) spinifera Ledoyer, 1973; C. (D.) tattersalli Ledoyer, 1983; Ceradocus (Denticeradocus) vaderi sp. nov.; C. (D.) yandala Berents, 1983.Published as part of Alves, Jessika, Johnsson, Rodrigo & Senna, André R., 2019, A new species of Ceradocus Costa, 1853 (Senticaudata: Maeridae) from Ceará State, Northeastern Brazil, pp. 127-138 in Zootaxa 4555 (1) on page 128, DOI: 10.11646/zootaxa.4555.1.11, http://zenodo.org/record/262405
A sinfonia do sagrado em Castro Alves: (Deus, Eros e mãe em Os escravos)
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Literatura.No presente trabalho realiza-se uma leitura intertextual entre a Bíblia e Os escravos, coletânea de poemas de teor abolicionista do poeta romântico Antônio Frederico de Castro Alves (1847-1871), objetivando demonstrar que os textos poéticos arquitetam-se na desconstrução e reconstrução dos textos bíblicos. A leitura dos poemas centra-se nos personagens: Deus, Eros e Mãe, os quais conformam uma trindade poética/sagrada. A pesquisa divide-se em três movimentos: Prelúdios do sagrado no Romantismo, Tríade melódica e À guisa de coda: trindade poética. No primeiro efetuam-se algumas aproximações ao conceito do sagrado e aos Romantismos francês e brasileiro. O seguinte corresponde à leitura das composições, através das linhas melódicas: A dualidade de Deus, A ambivalência de Eros e O duplo calvário da Mãe escrava. E no último movimento amalgamam-se as inter-relações entre a trindade cristã e poética e os dramas bíblico e poético
Tonnoira distincta Bravo, Alves & Chagas, sp. nov.
No full textTonnoira distincta Bravo, Alves & Chagas, sp. nov. Figs. 1–10 Type material. BRAZIL, Amazonas, Presidente Figueiredo, Gruta Refúgio do Maragua, 02°03´02.64”S 59 ° 57´47.85 ”W (Alves et al. 2008 presents some comments about this cavern), 01.IV. 2006, Alves, V. col., holotype male (INPA); 36 paratype males, same locality, date, and collector as holotype (INPA, MZUEFS); 29 paratype females, same locality, date and collector as holotype (INPA, MZUEFS); 12 paratype males and 19 paratype females, same locality, and collector as holotype, 09.II. 2006 (INPA, MZUEFS); 6 paratype females, Gruta dos Animais, 02°03´02,64”S 59 ° 57´51.47 ”W, 04.III. 2006, Alves, V. col. (INPA, MZUEFS); 1 paratype male, Gruta dos Lages, 01º 59 ’ 41.3 ”S 60 º01’ 36.5 ”W, 07.V. 2006, Alves, V. col. (INPA). Description. Male. Head (Fig. 1): eyes separated by 0.5 facet diameter (Fig. 1); interocular suture inverted Y shaped (Fig. 1). Antenna: scape cylindrical 2.0X length of pedicel (Fig. 2); pedicel spherical (Fig. 2); flagellum with 14 flagellomeres; all flagellomeres cylindrical (Figs. 2, 3); first flagellomere 1.2 X length of second (Fig. 2); apiculus present in flagellomere 14 (Fig. 3); ascoids not visible. Palpus formula = 1.0: 2.6: 2.4: 2.9; last palpomere striated (Fig. 4). Wing (Fig. 5): Sc short; base of R 2 + 3 not attached to R 4; radial fork basal; and medial fork complete; R 5 ending at wing apex. Male terminalia: hypandrium narrow dorsally with median projection, and ventrally expanded posteriorly with two lateral spines and two arms anteriorly projected (Fig. 6); gonocoxite 0.84 X length of the gonostylus with a tuff of bristles along the interior margin (Fig. 6); gonostyli convergent, with pointed apex (Fig. 6); alveoli present along all of the gonostyle surface; epandrium rectangular with one foramen near the anterior margin. Cercopod 1.1 X length of epandrium, slightly curved (Fig. 8), with 2 tenacula, one apical and the other subapical (Fig. 9); sternite 10 smaller than tergite 10 (Fig. 7); aedeagus asymmetrical (Fig. 6); with two asymmetrical parameres reaching the level of the aedeagus apex (Fig. 6); aedeagal apodeme the same length as aedeagus, longer than wide, wider anteriorly than posteriorly; gonocoxal apodeme not fused at midline (Fig. 6). Female (Fig. 10). Similar to male except as follows: apical lobes of subgenital plate of female small, rounded at apex, and separated by a shallow concavity. Cerci blade-like, 2.7 X the total length of genital plate from the anterior border at middle to the lobe apices (distance d). Genital complex as illustrated.Published as part of Bravo, Freddy, Chagas, Cinthia & Alves, Veracilda Ribeiro, 2008, Description of two new species of Tonnoira Enderlein from caves in the Brazilian Amazon and comments about the taxonomic status of Tonnoira plumaria Quate (Diptera, Psychodidae, Psychodinae), pp. 63-68 in Zootaxa 1916 on page 65, DOI: 10.5281/zenodo.18461
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Tonnoira robusta Bravo, Alves & Chagas, sp. nov.
No full textTonnoira robusta Bravo, Alves & Chagas, sp. nov. Figs. 11–20 Type material. BRAZIL, Amazonas, Presidente Figueiredo, Gruta Refúgio do Maragua, 02°03´02.64”S 59 ° 57´47.85 ”W, 01.IV. 2006, Alves, V. col., holotype male (INPA); 1 paratype male, same locality, date, and collector as holotype (MZUEFS); 2 paratype males, same locality and collector as holotype, 06.V. 2006 (INPA, MZUEFS); 2 paratype males, same locality and collector as holotype, 09.II. 2006 (INPA, MZUEFS); 1 paratype female, same locality and collector as holotype, 09.II. 2006 (INPA). Description. Male. Head (Fig. 11): eyes separated by 0.5 facet diameters (Fig. 11); interocular suture inverted Y shaped (Fig. 11). Antenna: scape cylindrical 1.7 X length of pedicel (Fig. 12); pedicel spherical (Fig. 12); flagellum with 14 flagellomeres; all flagellomeres flask-shaped (Figs. 12, 13); first flagellomere same length as second (Fig. 12); apiculus present in flagellomere 14 (Fig. 13); ascoids not visible. Palpus formula = 1.0: 2.1: 1.9: 2.2; last palpomere striated (Fig. 14). Wing (Fig. 15): Sc short; vein R 2 + 3 obsolete, radial fork free; radial fork basal; medial fork complete; R 5 ending at wing apex. Male terminalia: hypandrium narrow, diademe-like without ventral expansion (Fig. 16); gonocoxite 0.6 X length of the gonostylus (Fig. 16); gonostyli convergent, with base larger than apex (Fig. 16); alveoli present along entire surface (Fig. 16); epandrium rectangular; foramen not observed (Fig. 17); cercopod long, 2.2 X length of epandrium, slightly curved (Fig. 18), with 2 tenacula, one apical and the other subapical (Fig. 19); sternite 10 smaller than tergite 10 (Fig. 17); aedeagus asymmetrical, bipartite with left branch smaller than right, curved, pointed at apex (Fig. 16); right branch of aedeagus with rounded apex (fig. 16); with two asymmetrical parameres ending near the apex of the aedeagus apex (Fig. 16); aedeagal apodeme trapezoidal, 0.75 x length of aedeagus, wider anteriorly than posteriorly (Fig. 16); gonocoxal apodeme not fused at midline (Fig. 16). Female (Fig. 20). Similar to male except as follows: apical lobes of subgenital plate of females long, rounded, and separated by a shallow apical concavity. Cerci blade-like, 2.2 X the total length of genital plate from the anterior border at middle to the lobe apices (distance d). Genital complex small, as illustrated.Published as part of Bravo, Freddy, Chagas, Cinthia & Alves, Veracilda Ribeiro, 2008, Description of two new species of Tonnoira Enderlein from caves in the Brazilian Amazon and comments about the taxonomic status of Tonnoira plumaria Quate (Diptera, Psychodidae, Psychodinae), pp. 63-68 in Zootaxa 1916 on pages 65-67, DOI: 10.5281/zenodo.18461
Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer
No full textThe presence of lymphatic metastases is a strong indicator for poor prognosis in patients with ductal pancreatic cancer. In order to better understand the mechanisms controlling lymphatic growth and lymph node metastasis in human ductal pancreatic cancer, we analyzed the expression pattern of the vascular endothelial growth factor-D (VEGF-D), its receptor VEGF-receptor-3 (VEGFR-3) and the lymphatic endothelium-specific hyaluronan receptor LYVE-1 in a panel of 19 primary human ductal pancreatic tumors and 10 normal pancreas specimens. We further addressed the biological function of VEGF-D for induction of lymphatic metastasis in a nude mouse xenograft model using two human ductal pancreatic cancer cell lines with overexpression of VEGF-D. Compared to normal human pancreas, pancreatic cancer tissue showed overexpression of VEGF-D and VEGFR-3 in conjunction with a high lymphatic vascularization as determined by immunohistochemistry and in situ hybridization. Tumors derived from VEGF-D-overexpressing cells had a higher microvessel density compared to their mock-controls, as determined based on CD31 immunohistochemistry. Importantly, these tumors also revealed a significant induction of intra- and peritumoral lymphatics, as judged from inmunohistochemical detection of LYVE-1 expression. This was associated with a significant increase in lymphatic vessel invasion by tumor cells and an increased rate of lymphatic metastases, as indicated by pan-cytokeratin reactive cells in lymph nodes. Our results suggest that VEGF-D plays a pivotal role in stimulating lyrnphangiogenesis and lymphatic metastasis in human ductal pancreatic cancer, and therefore represents a novel therapeutic target for this devastating disease
Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer
No full textThe presence of lymphatic metastases is a strong indicator for poor prognosis in patients with ductal pancreatic cancer. In order to better understand the mechanisms controlling lymphatic growth and lymph node metastasis in human ductal pancreatic cancer, we analyzed the expression pattern of the vascular endothelial growth factor-D (VEGF-D), its receptor VEGF-receptor-3 (VEGFR-3) and the lymphatic endothelium-specific hyaluronan receptor LYVE-1 in a panel of 19 primary human ductal pancreatic tumors and 10 normal pancreas specimens. We further addressed the biological function of VEGF-D for induction of lymphatic metastasis in a nude mouse xenograft model using two human ductal pancreatic cancer cell lines with overexpression of VEGF-D. Compared to normal human pancreas, pancreatic cancer tissue showed overexpression of VEGF-D and VEGFR-3 in conjunction with a high lymphatic vascularization as determined by immunohistochemistry and in situ hybridization. Tumors derived from VEGF-D-overexpressing cells had a higher microvessel density compared to their mock-controls, as determined based on CD31 immunohistochemistry. Importantly, these tumors also revealed a significant induction of intra- and peritumoral lymphatics, as judged from inmunohistochemical detection of LYVE-1 expression. This was associated with a significant increase in lymphatic vessel invasion by tumor cells and an increased rate of lymphatic metastases, as indicated by pan-cytokeratin reactive cells in lymph nodes. Our results suggest that VEGF-D plays a pivotal role in stimulating lyrnphangiogenesis and lymphatic metastasis in human ductal pancreatic cancer, and therefore represents a novel therapeutic target for this devastating disease
SBM flow statistics over a grit-blasted surface
No full textData created and presented by F. Alves Portela and N. D. Sandham, "A DNS/URANS approach for simulating rough-wall turbulent flows". International Journal of Heat and Fluid Flow. 2020 (doi: 10.​1016/​j.​ijheatfluidflow.​2020.​108627) as well as height maps of the two surfaces considered.</span
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