1,721,044 research outputs found
On the physiological role of 5'-nucleotidase II (cN-II): Pathological and therapeutical implications
No full textEnzymatic synthesis of purine 2'-deoxyriboside and its properties as an inhibitor of adenosine deaminases from calf intestinal mucosa and Bacillus cereus
No full textEnzymatic synthesis of purine 2'-deoxyriboside was obtained by reacting purine with excess 2-deoxy-alpha-D-ribose-1-phosphate in the presence of commercial bovine nucleoside phosphorylase; the product was isolated by semipreparative reverse phase HPLC with an overall 62% yield. Purine 2'-deoxyriboside was shown to behave as a competitive inhibitor of adenosine deaminase from calf intestinal mucosa and Bacillus cereus, with apparent Ki values of 4.5 and 8.5 microM, respectively
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Expression and characterisation of recombinant bovine cytosolic 5'-nucleotidase IMP-GMP specific
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Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Oocyte retrieval in superstimulated buffalo heifers.
No full textEmbryo production following oocytes in vitro fertilization is related on number of oocytes collected by Ovum pick-up. The objective of this study was to compare stimulated peripuberal buffaloes and to assess ovarian response and oocyte recovery. On day 0, 12 heifers undergone clinical examination of genital tract by ultrasound and a progesterone releasing intravaginal device was inserted into the animals. On day 3 buffaloes were divided into two treatment groups , according to their age, body weight and follicular population on day 0 and 3. On day 7 all buffaloes undergone ultrasound examination and number and size of the follicles was recorded. Heifers in Group A (n=6) received a 4-day decreasing dosage of an equal mixture of 500 I.U. of Follicle Simulating Hormone and 500 I.U. of Luteinizing hormone; Group B (n=6) received a single i.m. injection of Pregnant Mare Serum Gonadotrophin and a 2-day decreasing dosage of an equal mixture of 175 I.U. of FSH and 175 I.U. of LH, starting on day 5. Group B resulted in a significantly higher (P<0.05) number of large-very large follicles compared to group A (13.2 vs 8.3). Although no significant differences, in group A and B, were found on the number of observed follicles (14.2 vs 18.2), aspirated follicles (11.5 vs 14.0), recovered oocytes (6.33 vs 6.5) and percentage of recovered oocytes/aspirated follicles (60,0 vs 44.8), all the parameters tended to be higher in group A. The percentage of viable oocytes (3.2 vs 3.2) was similar. Protocol B stimulated the recruitment and the growth of a higher number of small follicles. It is possible to hypothise that the higher size of the follicles in group B, caused the lost of follicular fluid affecting oocyte recovery
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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