1,720,990 research outputs found
Tinea Incognita following the Use of an Antipsoriatic Gel
Tinea incognita is a dermatophyte infection of the skin whose clinical presentation has been modified by the misuse of steroids or, as has been described recently, calcineurin inhibitors. We report a case of pustular psoriasis treated with an antipsoriatic cream, composed of topical steroids and a vitamin D3 derivative, which gave rise to a tinea incognita. Our case underlines that clinical features of fungal infection can be modified by the increasing use of self-prescribed topical therapies, usually applied to treat incorrectly 'self-diagnosed' diseases. Moreover, we suggest that a mycological examination should be performed in every atypical presentation of skin lesion, and to rule out tinea pedis, in any disease of the feet that requires topical application of steroids
Reflectance confocal microscopy and dermoscopic features of acrodermatitis continua of Hallopeau
eflectance confocal microscopy and dermoscopic features of acrodermatitis continua of Hallopea
Evaluation of efficacy and tolerability of four weeks bifonazole treatment after nail ablation with 40% urea in mild to moderate distal subungual onychomycosis
The aim of this study was to verify efficacy and tolerability of sequential therapy with 40% urea paste followed by 1% bifonazole urea in mild to moderate distal subungual onychomycosis of the toenails
Le unghie dei piedi. Manuale pratico per la gestione delle onicopatie. Ediz. ampliata
Le malattie delle unghie rappresentano un settore specialistico della dermatologia e sono spesso poco conosciute. In particolare, le onicopatie dei piedi rappresentano oggi un campo in cui dermatologo e podologo collaborano al fine di garantire un’ottimale gestione del paziente, che può così beneficiare di diagnosi e terapia di competenza specialistica, ma anche di trattamenti periodici da parte del podologo.
L’intento di questo libro è fornire una visione schematica e immediata delle patologie ungueali, facilitata dalla presenza di numerose fotografie, per rendere il lettore in grado di effettuare una pronta diagnosi e gestire il paziente nel modo più opportuno.
In questa seconda edizione è stato aggiunto un focus sulle unghie delle mani, che possono presentare patologie esclusive e diverse da quelle dei piedi
Squamous cell carcinoma of the nail unit
Squamous cell carcinoma (SCC) of the nail apparatus is a rare malignant tumor that usually originates underneath the nail plate and grows slowly with possible bone invasion. The etiology remains unknown, although a strong association with different conditions, such as high-risk human papillomavirus (HPVs), trauma, or radiation exposure has been demonstrated. Nail SCC is called "the great mimicker nail tumor" because different clinical presentations may coexist, resembling benign or malignant nail lesions. For this reason, there is often a significant delay between the onset of nail SCC and the diagnosis. Clinical manifestation includes onycholysis and erythema, while in the advanced stages nail ulceration can be observed. The association with pain, swelling, and inflammation usually indicates an invasive SCC with involvement of the underlying bone. Metastasis is rare but possible with involvement of lymph nodes. A multidisciplinary approach to assessment, management, and follow-up is advised. Using careful examination and modern diagnostic methods, including onychoscopy, biopsy, and histopathology, will help identify SCC and prevent the invasive progression. X-ray is important to investigate the bone invasion to determine the best surgical approach that will have satisfying cosmetic and functional outcomes. Nevertheless, local excision with sufficient surgical margins, best if using Mohs surgery, is usually sufficient and superior to amputation of the distal phalanx. This review aims to highlight the correct approach in suspected SCC of the nail unit
Short anagen syndrome: A case series and algorithm for diagnosis.
Background: The short anagen syndrome (SAS) is a rare idiopathic pediatric disorder
characterized by the short duration of the anagen phase. SAS mainly affects
Caucasian children. Parents complain of their child's inability to grow long hair.
Topical minoxidil may be an effective treatment for SAS; however, a slow spontaneous
improvement is typical.
Objective: Our aim was to collect data on out cases of SAS and create an algorithm
to facilitate diagnosis of SAS.
Methods: A retrospective review of 25 patients with SAS was performed within the
Dermatology Department of the University of Bologna. We collected data regarding
symptoms, pull test, hair card test, trichoscopy, trichogram, treatments, including
biotin and minoxidil, and clinical outcome.
Results: Characteristic findings included parental reporting that the hair had not required
a haircut, hair card test showing hairs with conical-shaped
tips, and hair shafts
of different diameters, with more 10%-20%
of hair shafts less than 60 μm thick on trichoscopy.
Trichogram revealed an increased percentage of telogen hair with normal
hair shafts and tapering ends. The mean anagen-to-
telogen
ratio was 66:34 (normal
ratio 90:10).
Conclusion: We developed an algorithm to facilitate the diagnosis of this rare hair
disease using clinical examination and invasive and non-invasive
testing to differentiate
SAS from other forms of pediatric alopecia. In conclusion, the collected data of
the therapy showed that biotin alone or in combination with topical minoxidil is an
effective treatment for SAS
The importance of reflectance confocal microscopy for the diagnosis and the follow-up of tinea capitis
[No abstract available
la dermatite da contatto: frequente complicanza delle ulcere croniche degli arti inferiori
dermatite da contatto nelle ulcer
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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