1,354,256 research outputs found

    Biotransformación de Cr(VI) mediada por bacterias y su aplicación en sistemas de tratamiento de aguas residuales industriales

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    Las aguas residuales provenientes de galvanoplastias, de la industria metalúrgica y la industria química presentan concentraciones de Cr(VI) por encima de los niveles permitidos por ley para su descarga en cuerpos de agua receptores o en plantas de tratamiento cloacal. Por lo tanto, estas industrias deben tratar sus aguas previamente a la descarga. Sin embargo, los tratamientos convencionales del tipo químico son muchas veces ineficientes y costosos. En el presente trabajo se desarrolla un sistema de tratamiento biológico que es más económico, eficiente y ambientalmente amigable. El tratamiento consiste en la utilización de un biocatalizador inmovilizado en una matriz inerte para la reducción de Cr(VI) a Cr(III). Los parámetros óptimos de funcionamiento del tratamiento fueron determinados y los costos fueron optimizados. Se demostró la viabilidad del tratamiento para aguas con bajo contenido de Cr(VI).Fil: Alessandrello, Mauricio Javier. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Platelet function tests: a comparative review

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    Rita Paniccia,1,2 Raffaella Priora,1,2 Agatina Alessandrello Liotta,2 Rosanna Abbate1,2 1Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Florence, Italy; 2Department of Heart and Vessels, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy Abstract: In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet defects promote bleeding, whereas the high residual reactivity of platelets in patients on antiplatelet therapies moves forward thromboembolic complications. The biochemical mechanisms of the different phases of platelet activation – adhesion, shape change, release reaction, and aggregation – have been well delineated, whereas their complete translation into laboratory assays has not been so fulfilled. Laboratory tests of platelet function, such as bleeding time, light transmission platelet aggregation, lumiaggregometry, impedance aggregometry on whole blood, and platelet activation investigated by flow cytometry, are traditionally utilized for diagnosing hemostatic disorders and managing patients with platelet and hemostatic defects, but their use is still limited to specialized laboratories. To date, a point-of-care testing (POCT) dedicated to platelet function, using pertinent devices much simpler to use, has now become available (ie, PFA-100, VerifyNow System, Multiplate Electrode Aggregometry [MEA]). POCT includes new methodologies which may be used in critical clinical settings and also in general laboratories because they are rapid and easy to use, employing whole blood without the necessity of sample processing. Actually, these different platelet methodologies for the evaluation of inherited and acquired bleeding disorders and/or for monitoring antiplatelet therapies are spreading and the study of platelet function is strengthening. In this review, well-tried and innovative platelet function tests and their methodological features and clinical applications are considered. Keywords: platelets, method, point-of-care testing, laboratory assessment, bleeding, thrombosi
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