1,721,058 research outputs found

    A flexible transaction framework for dynamic collaboration of agents-with an online travel application

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    The advancement of Internet-based commerce has created a turbulent market environment by allowing easier introduction of new products, services, and suppliers. For this dynamic environment, information systems need to be designed in a flexible way to meet the changing requirements. This paper proposes a flexible transaction framework for multi-agent systems so that agent systems can adapt to various types of changes in the dynamic electronic market environment. The flexible transaction framework consists of a flexible conversation model (FCM) for agents and an ontology meta-model called TOO (Task-Oriented Ontology) for the specific requirements of FCM. FCM permits agents to use newly acquired conversation policies that are induced by the frequent changes in transaction methods. Since FCM requires agents to be aware of a broader set of ontology entities, TOO is used to reduce the complexity of the ontology design and implementation for FCM. The flexible transaction framework is illustrated with an online traveling system developed for Korean domestic transportation services. The prospective synergy between the present work and Web services is discussed in the discussion section

    Agent-based adaptive travel planning system in peak seasons

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    With the wide spread of Internet, intelligent systems to support travel planning have been progressed during last decade. The current on-line travel support systems, however, have limits in their capabilities to adapt to the changes in travel plans. When the preferred travel plan is not available, especially during peak seasons, a traveler needs to re-plan by compromising his or her preferences, which requires time consuming and cumbersome efforts. This paper introduces an adaptive travel planning system with intelligent agent that can adapt to the dynamics of travel plans. This system consists of an adaptive travel-planning model, which is served as knowledge for agent to find alternatives and choose the best one, and a collaboration mechanism between the agents. This system provides more acceptable travel plans to travelers while reducing the risk of having no ticket in hand. The usefulness of the system is illustrated using a specific travel planning scenario. (C) 2004 Elsevier Ltd. All rights reserved

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Crystallization and preliminary X-ray crystallographic analysis of tRNA(m(1)G37)methyltransferase from Haemophilus influenzae

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    The enzyme tRNA(m(1)G37)methyltransferase (TrmD) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) specifically to guanosine at position 37 within a subset of tRNA species in bacteria. The modified guanosine is next to the anticodon and is important for the maintenance of the correct reading frame during translation. TrmD from Haemophilus influenzae with both Nand C-terminal tags was overexpressed in Escherichia coli and crystallized at 297 K using sodium acetate as a precipitant. Native X-ray diffraction data were collected to 1.85 Angstrom resolution. The crystals are rhombohedral, belonging to the space group R32, with unit-cell parameters a = b = 98.05, c = 176.79 Angstrom, alpha = beta = 90, gamma = 120degrees. The presence of one monomer of recombinant TrmD in the crystallographic asymmetric unit gives a V-M of 3.07 Angstrom(3) Da(-1) and a solvent content of 59.9%.

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Attentional bias induced by viewing actual or illusory movements

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    Objective: To learn to which portions of a line normal subjects would attend when watching this line actually moving or when perceiving movement even in the absence of actual movement, an illusory movement. Methods: Twenty normal subjects watched a computer monitor on which either lines or dots moved to the right or left. They also watched stationary lines, which appeared to be moving to the left or right because the background was moving in the opposite direction. While watching these lines or dots, their eye movements were monitored to determine the position of fixation. Results: Overall, subjects fixated on the side of the line that was in the direction of real or illusory movement. In the actual movement condition, leftward motion induced more of an attentional bias than rightward motion. In the illusory movement condition, however, rightward illusory movement condition induced more of an attentional bias than leftward movement. Conclusions: Objects moving leftward or rightward primarily activate the contralateral hemisphere. This hemispheric activation may induce a contralateral overt orienting response that is reflected by eccentric eye fixation. Treatments of neglect, such as caloric vestibular stimulation, may alter an attentional bias by inducing the illusion of movement

    Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition

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    tRNA(m(1)G37)methyltransferase (TrmD) catalyzes the transfer of a methyl group from S-adenosyl-l- methionine (AdoMet) to G(37) within a subset of bacterial tRNA species, which have a G residue at the 36th position. The modified guanosine is adjacent to and 3' of the anticodon and is essential for the maintenance of the correct reading frame during translation. Here we report four crystal structures of TrmD from Haemophilus influenzae, as binary complexes with either AdoMet or S-adenosyl-l-homocysteine (AdoHcy), as a ternary complex with AdoHcy and phosphate, and as an apo form. This first structure of TrmD indicates that it functions as a dimer. It also suggests the binding mode of G(36)G(37) in the active site of TrmD and the catalytic mechanism. The N-terminal domain has a trefoil knot, in which AdoMet or AdoHcy is bound in a novel, bent conformation. The C-terminal domain shows structural similarity to trp repressor. We propose a plausible model for the TrmD(2)-tRNA(2) complex, which provides insights into recognition of the general tRNA structure by TrmD.
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