1,721,069 research outputs found
Infliximab treatment in Psoriatic Arthritis: our experience
No full textThe aim of this work was to give clinical practice recommendations on the use of tumour necrosis factor blocking agents in psoriatic arthritis, underlining the pathogenetic mechanism of this condition and its articular and dermatologic manifestations. We retrace the stages leading to the therapeutic indications of biological agents that are presently used in the treatment of psoriatic arthritis: Entanercept, Adalimumab, Infliximab. We also report our personal experience describing an emblematic case of a patient with psoriatic arthritis in which a decisive regression of joint/skin involvement was obtained with Infliximab treatment
Optimization of the Parameters of Aa Formant Speech Synthesizer Using Genetic Algorithms
No full text
A formal instructional model based on Concept Maps
No full textThe aim of this paper is to show a new model (under development by the E-Learning & Knowledge Management Laboratory at the University of Genoa) for designing and developing units of learning. The idea behind this model comes from the analysis of the difficulties and problems that teachers have in their work during the instructional design of courses and training aids, and from a study on the latest semantic web technologies in order to support the sharing and the retrieval of web learning resources. The authors will also present the draft version of CADDIE (Content Automated Design & Development Integrated Editor), a software tool under development at the E-Learning & Knowledge Management Laboratory of the University of Genoa, whose core is based on the model described here and whose aim is to provide an innovative solution to the learning content of the instructional design process, based on an ontological structure
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