1,721,053 research outputs found

    A Survey on Information and Communication Technologies for Industry 4.0: State-of-the-Art, Taxonomies, Perspectives, and Challenges

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    A new industrial revolution is undergoing, based on a number of technological paradigms. The will to foster and guide this phenomenon has been summarized in the expression “Industry 4.0” (I4.0). Initiatives under this term share the vision that many key technologies underlying Cyber-Physical Systems and Big Data Analytics are converging to a new distributed, highly automated, and highly dynamic production network, and that this process needs regulatory and cultural advancements to effectively and timely develop. In this work, we focus on the technological aspect only, highlighting the unprecedented complexity of I4.0 emerging from the scientific literature. While previous works have focused on one or up to four related enablers, we consider ten technological enablers, including besides the most cited Big Data, Internet of Things, and Cloud Computing, also others more rarely considered as Fog and Mobile Computing, Artificial Intelligence, Human-Computer Interaction, Robotics, down to the often overlooked, very recent, or taken for granted Open-Source Software, Blockchain, and the Internet. For each we explore the main characteristics in relation to I4.0 and its interdependencies with other enablers. Finally we provide a detailed analysis of challenges in leveraging each of the enablers in I4.0, evidencing possible roadblocks to be overcome and pointing at possible future directions of research. Our goal is to provide a reference for the experts in some of the technological fields involved, for a reconnaissance of integration and hybridization possibilities with other fields in the endeavor of I4.0, as well as for the laymen, for a high-level grasp of the variety (and often deep history) of the scientific research backing I4.0

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    A hierarchical hybrid intrusion detection approach in IoT scenarios

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    Internet of Things (IoT) fosters unprecedented network heterogeneity and dynamicity, thus increasing the variety and the amount of related vulnerabilities. Hence, traditional security approaches fall short, also in terms of resulting scalability and privacy. In this paper we propose H2ID, a two-stage hierarchical Network Intrusion Detection approach. H2ID performs (i) anomaly detection via a novel lightweight solution based on a MultiModal Deep AutoEncoder (M2-DAE), and (ii) attack classification, using soft-output classifiers. We validate our proposal using the recently-released Bot-IoT dataset, inferring among four relevant categories of attack (DDoS, DoS, Scan, and Theft) and unknown attacks. Results show gains of the proposed M2-DAE in the case of simple anomaly detection (up to -40% false-positive rate when compared with several baselines at same true positive rate) and for H2ID as a whole when compared to the best-performing misuse detector approach (up to ≈ +5% F1 score). Besides the performance advantages, our system is suitable for distributed and privacy-preserving deployments while limiting re-training necessities, in line with the high efficiency as well as the flexibility required in IoT scenarios

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Encrypted Multitask Traffic Classification via Multimodal Deep Learning

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    Traffic Classification (TC), i.e. the collection of procedures for inferring applications and/or services generating network traffic, represents the workhorse for service management and the enabler for valuable profiling information. Sadly, the growing trend toward encrypted protocols (e.g. TLS) and the evolving nature of network traffic make TC design solutions based on payload-inspection and machine learning, respectively, unsuitable. Conversely, Deep Learning (DL) is currently foreseen as a viable means to design traffic classifiers based on automatically-extracted features, reflecting the complex patterns distilled from the multifaceted (encrypted) traffic nature, implicitly carrying information in multimodal fashion. To this end, in this paper a novel multimodal DL approach for multitask TC is explored. The latter is able to capitalize traffic data heterogeneity (by learning both intra- and inter-modality dependencies), overcome performance limitations of existing (myopic) single-modality DL-based TC proposals, and solve different traffic categorization problems associated with different providers' desiderata. Based on a real dataset of encrypted traffic, we report performance gains of our proposal over (a) state-of-art multitask DL architectures and (b) multitask extensions of single-task DL baselines (both based on single-modality philosophy)

    The Role of Reactive Oxygen Species in Colorectal Cancer Initiation and Progression: Perspectives on Theranostic Approaches

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    Altered levels of reactive oxygen species (ROS) are recognized as one of the key factors in mediating tumor cell survival in the tissue microenvironment, where they play a role in the initiation, progression and recurrence/relapse of colorectal cancer (CRC). Tumor cells can adapt to oxidative stress (OS) using genetic or metabolic reprogramming in the long or short term. In addition, tumor cells defend themselves through positive regulation of antioxidant molecules, enhancing ROS-driven proliferation. Balanced oxidative eustress levels can influence chemotherapy resistance, allowing tumor cells to survive treatment. Secondary effects of chemotherapy include increased ROS production and redox stress, which can kill cancer cells and eliminate drug resistance. Anticancer treatments based on manipulating ROS levels could represent the gold standard in CRC therapy. Therefore, exploring the modulation of the response to OS in deregulated signaling pathways may lead to the development of new personalized CRC treatments to overcome therapy resistance. In this review, we explore the role of ROS in the initiation and progression of CRC and their diagnostic implications as biomarkers of disease. Furthermore, we focused on the involvement of ROS in different CRC therapeutic options, such as surgery, radiotherapy, theranostic imaging, chemotherapy and immunotherapy and other precision medicine approaches
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