1,720,974 research outputs found
Giambattista Vico, «Principij di Scienza Nuova»
No full textIl saggio chiarisce la genesi del frontespizio della "Scienza nuova" e del capitolo introduttivo ("Idea dell'opera"), aggiunto in un secondo tempo, quando ormai il resto del volume era stato stampato. La "dipintura" risulta cosi' una tavola sinottica che riassume con tutta la simbologia dei geroglifici il contenuto dell'intera opera
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Increased free testosterone but normal 5 alpha-reduced testosterone metabolites in obese premenopausal women.
No full textSomatostatina: Effetti sulla secrezione insulinica e sulla tolleranza glicidica in soggetti obesi.
No full textIncreased free testosterone but normal 5α-reduced testosterone metabolites in obese premenopausal women
No full textOBJECTIVE:
The aim of the study was to investigate whether the absence of increased 5 alpha-reductase activity explained the absence of hirsutism in premenopausal obese women with increased free testosterone (FT) levels.
DESIGN:
As in hyperandrogenicity there generally exists evidence for increased 5 alpha-reductase activity, we measured, as parameters of 5 alpha-reductase activity, plasma levels of 5 alpha-androstane-3 alpha,17 beta-diol glucuronide (ADG) and androsterone glucuronide (ADTG) as well as their precursor levels in obese women without hirsutism, obese hirsute women, non-obese hirsute women, and non-obese, non-hirsute women.
PATIENTS:
Eighty-two premenopausal women (20-45 years old) were studied, in four age matched groups: 39 controls, 18 obese without hirsutism, 11 non-obese hirsute and 14 obese hirsute women.
MEASUREMENTS:
Blood samples were taken between days 5 and 7 of the menstrual cycle. Steroid hormone levels were measured by radioimmunoassay. Free testosterone levels were measured by equilibrium dialysis.
RESULTS:
Compared to controls, mean free testosterone levels were increased (P less than 0.01) in obese, obese hirsute and hirsute patients, whereas mean DHEAS levels were increased in hirsute and obese hirsute (P less than 0.01), but not in obese, women. Mean androstanediol glucuronide levels were markedly increased in hirsute and obese hirsute patients (P less than 0.01), but not in obese women. Plasma androsterone glucuronide levels were increased in hirsute (P less than 0.01), in the normal range in obese hirsute, and decreased in obese women (P less than 0.01).
CONCLUSIONS:
These results show that, despite the presence of higher free testosterone levels, neither 5 alpha-reductase activity (as suggested by normal androstanediol glucuronide levels) nor adrenal androgen precursor levels (DHEAS) are increased in obese women without hirsutism
Increased free testosterone but normal 5 alpha-reduced testosterone metabolites in obese premenopausal women
No full textThe aim of the study was to investigate whether the absence of increased 5 alpha-reductase activity explained the absence of hirsutism in premenopausal obese women with increased free testosterone (FT) levels
Steroidogenesi surrenalica dopo stimolazione ripetuta con ACTH in donne con ipertricosi cotituzionale, ovarica e surrenalica.
No full text
- …
