5 research outputs found

    Uma análise da construção dicotômica das personagens de Cecília e Isabel em O Guarani, de José de Alencar

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    Trabalho de Conclusão de Curso (graduação)—Universidade de Brasília, Instituto de Letras, Departamento de Teoria Literária e Literaturas, 2020.Este trabalho tem por objetivo fazer uma breve análise da construção das personagens femininas de Isabel e Cecília da obra O Guarani, de José de Alencar, publicada pela primeira vez em 1857. Procura-se evidenciar a dicotomia das personagens em análise em relação aos estereótipos difundidos na sociedade do séc. XIX, que estabeleciam a mulher branca, loira e frágil como imagem de pureza e santidade e a mulher morena, de cabelos negros e olhos escuros como a imagem do pecado e da sedução. Com o intuito de traçar uma característica comum desse autor, foram utilizadas análises de personagens femininas de outras obras de Alencar, usando como base também textos de críticos literários brasileiros, como Antonio Candido.This work aims to make a brief analysis of the constructions of the female characters of Isabel and Cecilia from the book O Guarani, by José de Alencar, published for the first time in 1857. It seeks to highlight the dichotomy of the characters under analysis in relation to the widespread streotypes in the society of the century XIX, witch established the white, blonde and fragile woman as an image of purity and holiness and the brunette woman, with black hair and dark eyes as the image of sin and. In order to trace a common characteristic of this author, analyzes of female characters from others books by Alencar were used, also based on texts by Brazilian literary critics, such as Antonio Candido

    High levels of polypharmacy in rheumatoid arthritis—a challenge not covered by current management recommendations : data from a large real-life study

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    Rheumatoid arthritis (RA) is associated with high frequency of comorbidities and increased risk of polypharmacy. Although there is a great potential for complications, there is a gap in literature on polypharmacy in patients with rheumatic arthritis. To evaluate the prevalence and factors associated with polypharmacy in a population in a real-life setting. Methods: A cross-sectional multicenter study was conducted in Brazil. Patients underwent clinical evaluation and medical records analysis. Polypharmacy was considered as a dependent variable. To test independent variables, we used Poisson regression. We evaluated 792 patients (89% female, median age 56.6 years). Median duration of disease was 12.7 years, 78.73% had a positive rheumatoid factor. The median of disease activity score-28 was 3.5 (disease with mild activity), median of the clinical disease activity index score was 9, and median of health assessment questionnaire-disability index was 0.875; 47% used corticosteroids, 9.1% used nonsteroidal anti-inflammatory drugs, 90.9% used synthetic disease-modifying antirheumatic drugs, 35.7% used biologic disease-modifying antirheumatic drugs (DMARDs). In total, 537 (67.9%) patients used 5 or more drugs. Polypharmacy showed a relationship with a number of comorbidities and use of specific drugs (corticosteroids, methotrexate, and biological DMARDs). We found a high prevalence of polypharmacy (67.9%) in RA. Solutions to management this problem should be stimulatedThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Brazilian Society of Rheumatology (BSR). For this project, BSR received specific grant support from the following companies: Bristol-Myers Squibb Farmacêutica Ltda; Eli Lilly do Brasil Ltda; Janssen-Cilag Farmacêuticos Ltda; Laboratórios Pfizer Ltda; Produtos Roche Químicos e Farmacêuticos S.A.; and UCB Biopharma Ltda. The funding body or the companies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscrip

    Cranial nerve VI palsy as a rare initial presentation of systemic lupus erythematosus: Case report and review of the literature

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    A 48-year-old woman presented with isolated sixth cranial nerve palsy. She subsequently developed systemic lupus erythematosus (SLE) based on clinical and laboratory parameters. Three years later, she presented again with sixth cranial nerve palsy affecting the contralateral eye. Within 2 weeks of steroid initiation, complete recovery occurred. The unusual rare presentation of SLE in the current patient, as well as the pathogenesis and treatment of cranial neuropathy in SLE are discussed. Lupus (2010) 19, 201-205.Arbuckle MR, 2003, NEW ENGL J MED, V349, P1526, DOI 10.1056-NEJMoa021933; ASHERSON RA, 1985, J RHEUMATOL, V12, P1029; ASHERSON RA, 1990, J RHEUMATOL, V17, P1292; ASHERSON RA, 1986, J RHEUMATOL, V13, P416; ASHERSON RA, 1983, BRIT MED J, V287, P1024; ASZKENASY OM, 1987, ANN RHEUM DIS, V46, P246, DOI 10.1136-ard.46.3.246; Balestrieri G, 1996, CLIN EXP RHEUMATOL, V14, pS3; BOWMAN CA, 1986, OTOLARYNG HEAD NECK, V94, P197; Bruns A, 2006, JOINT BONE SPINE, V73, P639, DOI 10.1016-j.jbspin.2006.05.006; CALDARELLI DD, 1986, AM J OTOL, V7, P210; Compadretti GC, 2005, ANN OTO RHINOL LARYN, V114, P214; ESPANA A, 1990, NEUROLOGY, V40, P1143; EVANS OB, 1978, ANN NEUROL, V4, P584, DOI 10.1002-ana.410040630; FRIEDMAN AS, 1995, CLIN NEPHROL, V44, P338; Galindo-Rodriguez G, 1999, AM J MED, V106, P65, DOI 10.1016-S0002-9343(98)00372-6; Genevay S, 2002, LUPUS, V11, P313, DOI 10.1191-0961203302lu205oa; Gomides APM, 2007, LUPUS, V16, P987, DOI 10.1177-0961203307084160; GORDON T, 1990, BRIT J RHEUMATOL, V29, P308; Green L, 2001, CLIN RHEUMATOL, V20, P220, DOI 10.1007-s100670170069; HAMBLIN TJ, 1982, BRIT MED J, V284, P1374; Hochberg MC, 1997, ARTHRITIS RHEUM, V40, P1725, DOI 10.1002-art.1780400928; Imauchi Y, 2001, ORL J OTO-RHINO-LARY, V63, P53, DOI 10.1159-000055706; JOHNSON RT, 1968, MEDICINE, V47, P337, DOI 10.1097-00005792-196807000-00002; Karatas E, 2007, OTOLARYNG HEAD NECK, V136, P82, DOI 10.1016-j.otohns.2006.06.1255; Kastanioudakis I, 2002, J LARYNGOL OTOL, V116, P103; Kataoka Hideyuki, 1995, Auris Nasus Larynx, V22, P53; KEANE JR, 1995, ARCH NEUROL-CHICAGO, V52, P1145; Khalidi NA, 2008, J LARYNGOL OTOL, V122, P1371, DOI 10.1017-S0022215108001783; KOBAYASHI S, 1992, INTERNAL MED, V31, P778, DOI 10.2169-internalmedicine.31.778; KRAUS A, 1990, ANN RHEUM DIS, V4, P421; Kwok SK, 2008, J KOREAN MED SCI, V23, P153, DOI 10.3346-jkms.2008.23.1.153; LANHAM JG, 1982, POSTGRAD MED J, V58, P688; Lee JH, 2008, AM J PHYS MED REHAB, V87, P68, DOI 10.1097-PHM.0b013e31815b669e; Lee JS, 2000, J PEDIAT OPHTH STRAB, V37, P241; MCDONALD E, 1992, HOSP PRACT, V27, P41; Miyakis S, 2006, J THROMB HAEMOST, V4, P295, DOI 10.1111-j.1538-7836.2006.01753.x; Naarendorp M, 1998, J RHEUMATOL, V25, P589; Peeva E, 2001, SCAND J RHEUMATOL, V30, P45; Peters GB, 2002, OPHTHALMOLOGY, V109, P1925, DOI 10.1016-S0161-6420(02)01226-5; ROSENSTEIN ED, 1989, J CLIN NEURO OPHTALM, V4, P285; Roverano S, 2006, JCR-J CLIN RHEUMATOL, V12, P217, DOI 10.1097-01.rhu.0000242777.71604.69; SALUJA S, 1989, CLIN EXP RHEUMATOL, V7, P81; Sanna G, 2003, J RHEUMATOL, V30, P985; SEDWICK L, 1987, J CLIN NEURO OPHTALM, V7, P69; Sharma A, 1988, J Assoc Physicians India, V36, P674; Sivaraj RR, 2007, RHEUMATOLOGY, V46, P1757, DOI 10.1093-rheumatology-kem173; Teoh SCB, 2001, CLIN EXP OPHTHALMOL, V29, P213, DOI 10.1046-j.1442-9071.2001.00424.x; Toubi E, 2000, ISRAEL MED ASSOC J, V2, P243; Vaile JH, 1998, J RHEUMATOL, V25, P2287; VYSE T, 1994, J LARYNGOL OTOL, V108, P57; Yu KH, 2007, LUPUS, V16, P746, DOI 10.1177-0961203307080632; 1999, ARTH RHEUM, V42, P59955
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