181,944 research outputs found
Wits Architecture Student Works 1922-1980; Calderwood, DM 1942 5th year B Arch.
No full textWits Architecture Student Works 1922-1980; Calderwood, DM 1941, 1942; Latin Club - (undated); Preliminary drawing for a Proposed new Seafront Maritime Hotel, Muizenberg, Cape, Perspective, 4th year; Victory Exposition to be held at Zoo-lake, Johannesburg, 1942, B Arch V.Wits Architecture Student Works 1922-1980; Calderwood, DM 1941, 1942; Latin Club - (undated); Preliminary drawing for a Proposed new Seafront Maritime Hotel, Muizenberg, Cape, Perspective, 4th year; Victory Exposition to be held at Zoo-lake, Johannesburg, 1942, B Arch V
HMM-DM
No full text<p><strong>HMM-DM: Identifying Differentially Methylated Regions using a Hidden Markov Model</strong></p>
Does diabetes mellitus play a role in restenosis and patency rates following lower extremity peripheral arterial revascularization? A critical overview
No full textPatients with diabetes mellitus (DM) are at increased risk of developing lower extremity peripheral arterial disease (PAD). The effect of DM on restenosis and patency rates in patients with PAD undergoing surgical revascularization or percutaneous interventions has not been fully clarified. We therefore critically reviewed the role of DM in restenosis, as well as primary and secondary patency rates in these patients. We searched Medline for studies investigating the effect of DM on restenosis (primary and secondary patency) rates in patients undergoing surgical/percutaneous interventions for the treatment of lower extremity PAD. Search terms used were "diabetes and peripheral arterial disease," "angioplasty," "restenosis," "revascularization," "patency rates," and "in-stent restenosis." Diabetic patients with PAD have similar restenosis, primary patency, and secondary patency rates compared with nondiabetic patients. However, mortality and amputation rates are increased in patients with DM. This increased risk of mortality and amputation may distort the estimation of restenosis and patency rates. Strict glucose control should be implemented in diabetic patients. Additionally, the use of antiplatelet agents and statins may have a beneficial effect on restenosis and patency rates. The role of radiation therapy in preventing restenosis remains to be determined. Patients with PAD and DM should receive optimal medical therapy to improve cardiovascular outcome and decrease functional decline. The direct involvement of vascular surgeons in the management of PAD patients is essential to reduce the incidence of cardiovascular events and mortality rates
KDD, SEMMA and CRISP-DM: a parallel overview
No full textIn the last years there has been a huge growth and consolidation of the Data Mining field. Some efforts are being done that seek the establishment of standards in the area. Included on these efforts there can be enumerated SEMMA and CRISP-DM. Both grow as industrial standards and define a set of sequential steps that pretends to guide the
implementation of data mining applications. The question of the existence of substantial differences between them and the traditional KDD process arose. In this paper, is pretended to establish a parallel between these and the KDD process as well as an understanding of the similarities between them
DM In-Depth: Level 1
No full textA look at the current status of the LSST Level 1 Nightly Alert Processing pipeline.Presented on behalf of LSST-DM at the 2016 LSST Project and Community Workshop DM plenary
PROV-DM : the PROV Data Model
No full textProcedencia es la información sobre entidades, actividades y personas involucradas en la producción de un grupo de datos, que puede ser usada para formar evaluaciones sobre su calidad, fiabilidad o veracidad. PROV-DM es el modelo conceptual de datos que sirve de base para la familia de especificaciones PROV de W3C. PROV-DM distingue estructuras fundamentales, que forman la esencia de la información sobre la procedencia, desde estructuras expandidas que atienden a usos más específicos sobre procedencia. PROV-DM se organiza en seis componentes, que se relacionan respectivamente con: entidades y actividades, y el momento en el que fueron creadas, utilizadas, o finalizadas; derivaciones de entidades a partir de entidades; agentes que tienen la responsabilidad de entidades que se generaron y actividades que ocurrieron; una noción de conjunto, un mecanismo de apoyo a la procedencia de la procedencia; propiedades para vincular las entidades que se refieren a una misma cosa; y colecciones que forman una estructura lógica para sus miembros.W3
How DM Communicates
No full textLSST Data Management (DM) is a large, distributed organization. Most of our communications happen through online platforms. Rather than shoehorn all of our communications onto one online platform, DM uses the best platform for each format of communication. This presentation describes each of these communication channels, and how they are used. Platforms include Slack, community.lsst.org, Confluence, Requests for Comments, Requests for Discussion, and technical notes.</p
tanner-trickle/EXCEED-DM: EXCEED-DM-v0.3.0
No full textNew Physics
Support for spin dependent wave functions for all valence to conduction transitions in scattering and absorption calculations.
Added many more examples with individual documentation.
Compute the dielectric from first principles in the scattering regime.
Compute more general self-energies for DM absorption calculations.
Under the hood
Major code factor, utilizing type structures for a much more modular code base, changed some parallelization schemes to better utilize O(1000) processors.
Updated build system from FoBiS to CMake.
See the CHANGELOG for more granular details
Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules
No full textMajor histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii). After removal of the invariant chain, peptides can be loaded onto class II molecules, a process catalyzed by human leukocyte antigen-DM (HLA-DM) molecules. Here we show that MHC class II compartments consist of two physically and functionally distinct organelles. Newly synthesized MHC class II/Ii complexes were targeted to endocytic organelles lacking HLA-DM molecules, where Ii degradation occurred. From these organelles, class II molecules were transported to a distinct organelle containing HLADM, in which peptides were loaded onto class II molecules. This latter organelle was not directly accessible via fluid phase endocytosis, suggesting that it is not part of the endosomal pathway. Uptake via antigen-specific membrane immunoglobulin resulted however in small amounts of antigen in the HLA-DM positive organelles. From this peptide-loading compartment, class II–peptide complexes were transported to the plasma membrane, in part after transit through endocytic organelles. The existence of two separate compartments, one involved in Ii removal and the other functioning in HLA-DM–dependent peptide loading of class II molecules, may contribute to the efficiency of antigen presentation by the selective recruitment of peptide-receptive MHC class II molecules and HLA-DM to the same subcellular location
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