1,090 research outputs found
Enicospilus pseudoculator Gadallah & Soliman 2017
No full textEnicospilus pseudoculator Gadallah & Soliman 2017 Enicospilus pseudoculator Gadallah & Soliman 2017:39,44; Figs 4G, 8C, 12C, 16C, 20C, 26C, 31C holotype ♀ from Saudi Arabia. Type material studied through illustrations in Gadallah et al. (2017). Material examined: IRAN: 2♂♂, Hormozgan Province, Sirik 70 km North of Minab, 19 Apr. 1992, 170 m. a. s., Mirz. / Badii leg. (HMIM); 1 unsexed specimen, Hormozgan Province, Jazireh-e Larak, 6 Mar. 1999, Gh. / Manz. leg. (HMIM); 1♀, Kerman Province, 25 km E. of Jiroft (Mijan), 28˚42"N, 57˚57"E, 27 May 2014, Mi. Halada leg. (OÖLM). Remarks: Recently described based on material collected in Saudi Arabia (Gadallah et al. 2017). Very closely related to Enicospilus affinis Hedwig, 1957 stat. rev. with minor differences in coloration. The two species may be conspecific (see remarks under E. affinis). Enicospilus pseudoculator has also previously been recorded from Iran under the erroneous name Enicospilus monostigma (Vollenhoven, 1879) in Ameri et al. (2016, Figs 5A–F).Published as part of Johansson, Niklas, Ameri, Ali, Riedel, Matthias, Talebi, Ali Asghar & Ebrahimi, Ebrahim, 2021, Contribution to the Ophioninae (Hymenoptera: Ichneumonidae) of Iran with the description of 16 new species and an illustrated key to the Eremotylus of the Western Palaearctic, pp. 151-206 in Zootaxa 5023 (2) on page 166, DOI: 10.11646/zootaxa.5023.2.1, http://zenodo.org/record/522565
Designing experiments to develop measurements for species catalytic recombination using actinometry and optical emission spectroscopy on silicon carbide
No full textSubmission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-08-01The student, Ali Soliman, accepted the attached license on 2023-07-17 at 11:16.The student, Ali Soliman, submitted this Thesis for approval on 2023-07-17 at 11:28.This Thesis was approved for publication on 2023-07-21 at 14:03.DSpace SAF Submission Ingestion Package generated from Vireo submission #19711 on 2023-12-04 at 17:18:51This thesis aims to present a study of surface catalytic recombination using optical emission actinometry. The focus of the aforementioned experimental approach is to determine the intensity ratios from specific Argon and atomic Oxygen spectral lines at various distances above the sample. Figuring the previously mentioned ratios will enable the accurate estimation of the recombination layer thickness as well as the recombination coefficient or efficiency of the sample material. The material of interest in this study is a ceramic, specifically Silicon Carbide. This ceramic is commonly applied as a coating on top of Reinforced Carbon-Carbon TPS, which is placed on locations that experience the highest temperatures during re-entry. Focus of the study shifted temporarily towards material science, specifically to create Silicon Carbide samples that could be resistively heated. SOL-GEL, a wet chemical procedure that was investigated and attempted as a method to produce a ceramic coating, was established as the most viable method via X-Ray diffraction
Unravelling Tinengotinib’s Mechanistic Landscape in Triple-Negative Breast Cancer Via Network Pharmacology and in Silico Simulation Techniques
No full textTriple-negative breast cancer (TNBC) is a highly aggressive and heterogeneous subtype with limited treatment options and poor clinical outcomes. Tinengotinib (TT-00420), a spectrum-selective multi-kinase inhibitor, has emerged as a promising candidate for targeting multiple dysregulated pathways in TNBC. This study employed an integrative in silico strategy—combining network pharmacology, molecular docking, molecular dynamics (MD) simulations, and binding free energy (MMGBSA) calculations—to investigate the therapeutic potential of tinengotinib. Network pharmacology revealed that tinengotinib modulates key TNBC-associated pathways, including PI3K-Akt, ErbB, and focal adhesion, which are central to proliferation, apoptosis, and therapy resistance. Molecular docking demonstrated strong binding affinities with hub proteins, particularly PTK2 (-10.7 kcal/mol), MAPK8 (-10.6 kcal/mol), EGFR (-9.5 kcal/mol), and ESR1 (-9.4 kcal/mol). MD simulations confirmed stable binding and favorable conformational dynamics across all complexes, with EGFR and PTK2 showing reduced solvent accessibility indicative of structural compaction, while ESR1, SRC, and MAPK8 displayed increased solvent exposure. MMGBSA analysis further validated the thermodynamic stability of these interactions, with PTK2 and MAPK8 exhibiting the most favorable binding free energies. Collectively, these results highlight tinengotinib’s multitarget mechanism through stable interactions with key oncogenic proteins, providing a strong molecular rationale for its continued clinical development in TNBC management
Thalassemia minor presenting with vitamin B12 deficiency, paraparesis, and microcytosis
No full textArwa Lardhi,1 Rania Alhaj Ali,1 Rola Ali,2 Tarek Mohammed1 1Internal Medicine Department, Doctor Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 2Umm al-Qura University, Mecca, Saudi Arabia Abstract: Vitamin B12 is essential for proper neurological functioning, and its deficiency may cause a wide range of neuropsychiatric and hematological manifestations. We report a case of a previously healthy 32-year-old female who was admitted to our hospital with sudden onset of bilateral lower limb paraparesis and loss of sensation. The serum level of vitamin B12 was mildly decreased with high methylmalonic acid and homocysteine levels. However, her complete blood count showed no evidence of anemia or macrocytosis; instead, her mean corpuscular volume was low. Hemoglobin electrophoresis showed thalassemia trait, and that probably masked the megaloblastic features of vitamin B12 deficiency. She responded fully to vitamin B12 replacement therapy. Keywords: thalassemia trait, microcytosis, pernicious anemia, paraparesis, cobalamin deficienc
From Islamic Fundamentalism to a New Life in the West: Ali Eteraz and the Muslim Comedy Memoir
No full textThis chapter analyses the Muslim memoir as a hybrid text that both authenticates and satirises the subjectivity of the narrator. Given the social capital of the memoir form, I argue that its trustworthiness is inverted by the author Ali Eteraz to question the premise of social trust. The memoir delineates social trust through the expression of piety and Muslim modernity articulated by the narrator in his different avatars. Eteraz’s satirical representations of himself invite the reader to read against the grain of the by now familiar Muslim fundamentalist-turned-Sufi story. He reverses the contexts of Islamist violence with the performativity of humour and it is in that humour that we can see traces of a multicultural coexistence and a rebuilding of social trust
sj-docx-1-urj-10.1177_03915603231222083 – Supplemental material for Risk factors of stone residual after retrograde intrarenal surgery: A prospective cohort study
No full textSupplemental material, sj-docx-1-urj-10.1177_03915603231222083 for Risk factors of stone residual after retrograde intrarenal surgery: A prospective cohort study by Mohamed Mahmoud Abdelfatah Zaza, Ahmed Mohamed Tawfeek, Tarek Abd El-Mageed Salem, Muhammad Ibrahim Salim Soliman and Mohammed Hassan Ali in Urologia Journal</p
Study of Ag nanoparticles in a polyacrylamide hydrogel dosimeters by optical technique
No full textThe dosimetric characteristics of hydrogel dosimeters based on polyacrylamide (PAC) as a capping agent incorporating silver nitrate as a radiation-sensitive material are investigated using UV-Vis spectrophotometry within the dose range 0–100 Gy. Glycerol was used in the hydrogel matrix to promote the dosimetric response and increase the radiation sensitivity. Upon exposing the PAC hydrogel to γ-ray, it exhibits a Surface Plasmon Resonance (SPR) band at 453 nm, and its intensity increases linearly with absorbed doses up to 100 Gy. The results are compared with the silver nitrate gel dosimeter. Glycerol of 15% in the hydrogel matrix enhances the radiation sensitivity by about 30%. PAC hydrogel dosimeter can be considered a near water equivalent material in the 400 keV–20 MeV photon energy range. At doses less than 15 Gy, the PAC hydrogel dosimeter retains higher radiation sensitivity than the gel dosimeter. The total uncertainty (2σ) of the dose estimated using this hydrogel is about 4%. These results may support the validity of using this hydrogel as a dosimeter to verify radiotherapy techniques and dose monitoring during blood irradiation
Enicospilus stenopsis Kohl 1905
No full textEnicospilus stenopsis Kohl, 1905 Fig. 8A–F Henicospilus stenopsis Kohl, 1905:225. Lectotype ♀ from Turkey in NHMW, examined Enicospilus abnormis Meyer, 1929:19. Type lost. Henicospilus crassus Morley, 1912. Holotype ♀ from India in OUMNH, not examined Enicospilus variegatorius (Morley, 1912) replacement name for E. variegatus Szépligeti, 1905:1430–1431. Holotype ♀ in HNHM, not examined. Henicospilus przewalskii Kokujev, 1909: 2–3. Lectotype ♀ from China in ZIN, not examined. Enicospilus splendidus Rousse, Soliman & Gadallah, 2017: 55–56. Figs. 5C, 9A, 13A, 17A, 21A, 28A, 32A, 33B, 33C. syn. nov. Holotype ♂ from Saudi Arabia studied through photos in Gadallah et al. (2017). Remarks: The type of Enicospilus stenopsis Kohl was collected in Repetek in present day Turkmenistan. The first record from Iran seems to be referred to by Hedwig (1957) as E. variegatus Szépligeti. The species has been recently recorded from Iran by Barhoei et al (2012), but we have not been able to find any specimen in the material examined in this study. Enicospilus stenopsis is distinguished from similar pale marked species by the weakly sclerotised proximal sclerite (Fig. 8E), the very narrow temples and in having the tarsal claws with only a few teeth (Fig. 8A–F). The pictures of the single type male of Enicospilus splendidus Rousse, Soliman & Gadallah, 2017 syn. nov. show that this is a male specimen of E. stenopsis and the two species are synonymous.Published as part of Johansson, Niklas, Ameri, Ali, Riedel, Matthias, Talebi, Ali Asghar & Ebrahimi, Ebrahim, 2021, Contribution to the Ophioninae (Hymenoptera: Ichneumonidae) of Iran with the description of 16 new species and an illustrated key to the Eremotylus of the Western Palaearctic, pp. 151-206 in Zootaxa 5023 (2) on page 167, DOI: 10.11646/zootaxa.5023.2.1, http://zenodo.org/record/522565
Poroelastic Solutions of Hydraulic Fracturing Problems Using Fast Multipole Boundary Element Method
No full textHydraulic fracturing (HF) of horizontal wells is an essential part of any unconventional field development activity. Hence, understanding the behavior of this process in horizontal wells is extremely important. A comprehensive study on the behavior of hydraulic fractures is highly dependent on the mathematical formulation of the problem, assumptions that are made to make the problem tractable, and numerical method that is utilized to solve the corresponding equations. Although the host medium of hydraulic fractures is porous and saturated, often this problem is solved using elasticity equations and adding a leak-off, or other parameters in an un-coupled fashion to the model. This approach ignores the fully-coupled essence of the problem and often gives inaccurate results. On the other hand, adding the necessary details makes the model inefficient when degree of freedom (DOF) increases. Another complexity that exists in the hydraulic fracturing problem is movement of the boundary, which makes it difficult to re-mesh the domain that is required by most of the domain-based numerical methods after each propagation event. The objective of this study is to develop a comprehensive yet efficient model to investigate the behavior of hydraulic fractures in poroelastic media. The theory of poroelasticity together with the displacement discontinuity method, and an efficient fast multipole algorithm are utilized to develop an efficient hydraulic fracture model.
Displacement Discontinuity Method (DDM) is a numerical method that is used in this study to solve the field equations of poroelasticity. This method belongs to a class of boundary element methods (BEM), which are suitable when the ratio of volume to surface is high. DDM is a special formulation of BEM for a medium containing discontinuities (e.g., fractures). It is based on considering the fracture as a line in 2D (or a surface in 3D) along which one defines quantities that take into account the discontinuity in displacements from one side of the fracture to the other. Despite the great advantages of this method over the domain methods, it suffers from dense coefficients matrices. These dense matrices are multiplied by a vector in several places, and make the method computationally inefficient in circumstances that time and/or space are discretized with so many elements. This may happen in hydraulic fracturing problems where multiple fractures propagating from one or more wells. It would also occur in three-dimensional problems where typically the number of elements exceeds a few thousands.
Additionally, including poroelasticity makes this method even more computationally intensive because of the necessity to build a time-marching procedure. The Fast Multipole Method (FMM) is a computational method to efficiently compute matrix-vector products with a controllable error. Unlike the conventional BEM, in FMM the interaction between far-field sources and influenced points are calculated by initially concentrating a cluster of far-field sources into a separate point, then the effect of these concentrated forces on each influenced point is calculated. A technique known as black-box fast multipole method (bbFMM) is used in a part of this study to improve the computational efficiency of the conventional fully-coupled poroelastic displacement discontinuity model while keeping its accuracy. This method uses the conventional hierarchical tree structure in FMM to separate the influencing (source) and influenced (target) points. It also uses the Chebyshev polynomials for kernel expansion instead of the analytical expansion used in a conventional FMM formulation.
In this study, the fully-coupled formulation of displacement discontinuity method with a fast multipole algorithm are used to develop an efficient poroelastic hydraulic fracture simulator. The simulator is used to study several problems such as refracturing of a horizontal well and fracturing of an infill well in a partially depleted reservoir. It is also used to examine the computational effectiveness and the accuracy of the new approach against the conventional displacement discontinuity approach in calculating stresses, displacements and pore pressure. A comparison between efficiencies and precisions of the developed fast multipole model and the conventional displacement discontinuity model is presented. The main contribution of this research can be categorized in two parts, namely modifications of the DDM algorithm and applications of the model. In the first part, a new algorithm is presented for the fully-coupled fast multipole displacement discontinuity method. Also, a new procedure is suggested for analyzing problems such as refracturing horizontal wells that requires coupling between pore pressure and stresses. The new approach, unlike the conventional approach, can handle pore pressure and stress changes, and refracture propagation in one simulator run. Moreover, solutions that are obtained by the fast multipole algorithm is compared with the conventional fully-poroelastic displacement discontinuity method. Also, the applicability of this algorithm in the fully-coupled displacement discontinuity method is established. On the application side, several applications such as refracturing a single well, infill drilling, and problems involving N-fractures are studied using the suggested algorithm and approaches.Petroleum Engineering, Department o
The Effect of a Computerized Program on Developing 9th Graders' Reading Comprehension Skills and their Attitudes towards Reading in Palestine
No full textThis study aimed at investigating the effect of a computerized program on developing ninth graders' reading comprehension skills and students' attitudes towards reading. The targeted reading comprehension skills were prediction, skimming, scanning, recognizing synonyms and antonyms, deducing meaning from context and relating the text to personal experience, opinion or evaluation. The researcher purposively chose a representative sample of (60) ninth graders from Deir Al Balah Preparatory "B" Boys' school which is run by UNRWA in the Gaza Strip. The participants were divided into two equivalent groups: each group had (30) students. The researcher used four tools: 1) a questionnaire for teachers to determine the most important reading comprehension skills for ninth graders, 2) an achievement test (Pre & Post), 3) the suggested computerized program for the reading texts included in the second-term of English for Palestine 9, and 4) an attitude scale (pre & post) to determine the students' attitudes towards reading. The results of the study revealed that the computerized program was effective to develop the reading comprehension skills for ninth graders. In addition, the study findings confirmed that the technological environment develops and enhances the students' attitudes towards learning in general and towards reading via computers in particular. In the light of these results, the researcher recommends that EFL Palestinian teachers should use computers as a tool of enhancing students' reading comprehension and developing their attitudes towards not only reading but also learning
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