3,701 research outputs found
Molecular cytogenetic characterization of a new case of patial trisomy 13 (13q11q13.2)Research letter
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Air-guided manual deep lamellar keratoplasty
No full textPURPOSE. To evaluate the efficacy of a new modified technique of deep lamellar keratoplasty (DLK). METHODS. Nine eyes of eight patients with keratoconus of moderate degree were included. All patients underwent DLK with manual dissection from a limbal side port after an air bubble injection in the anterior chamber. The patients underwent a complete ophthalmologic examination 6 months after the suture removal, evaluating best-corrected visual acuity, corneal thickness, endothelial cell count, and topographic astigmatism. RESULTS. One case (11.1%) was converted to penetrating keratoplasty because of microperforation. In the eight successful cases, 7 eyes (77.8%) achieved 20/30 or better visual acuity 6 months after suture removal. Mean postoperative pachymetry was 604.76 μm (SD 46.76). Specular microscopy 6 months after suture removal revealed average endothelial cell count of 2273/mm 2 (SD 229). CONCLUSIONS. This modified DLK technique is a safe and effective procedure and could facilitate, after a short learning curve, this kind of surgery with a low risk of conversion to penetrating keratoplasty
Impact of implementing a Choosing Wisely educational intervention into clinical practice: The CW-SIMI study (a multicenter-controlled study)
No full textObjectives: To evaluate the impact of an educational intervention based on the Italian Society of Internal Medicine Choosing Wisely (CW-SIMI) recommendations. Design: Multicenter, interventional, controlled study. Setting: Twenty-three acute-care hospital wards in Italy. Participants: 303 Physicians working in internal medicine wards. Intervention: An online educational course. Main outcomes: The rate of proton pump inhibitor (PPI) prescriptions, the number of days of central venous catheter (CVC) usage, and the duration of intravenous (IV) antibiotic prescriptions evaluated at one month (T1) and at six months (T2) after course completion. Patients admitted and discharged during a 30-day period before the educational intervention (T0, one year before T2) were considered the comparison group. Results: A total of 232 physicians completed the course, while 71 did not attend the course. Data from 608, 662, and 555 patients were analyzed at T0, T1, and T2, respectively. The rate of PPI prescriptions declined at one month (RR: 0.67, 95% CI: 0.52–0.87, p = 0.0005) and at six months (RR: 0.62, 95% CI: 0.46–0.84, p = 0.003), and the number of days of CVC usage was reduced at six months (9.13 days at T0 vs. 5.52 days at T2, p = 0.007). The duration of IV antibiotic prescriptions displayed a decreasing trend (7.94 days at T0 vs. 7.42 days at T2, p = 0.081). Conclusions: A simple online educational intervention based on the CW-SIMI recommendations was associated with a clinically relevant reduction in the usage of PPIs and CVCs. Further studies are needed to confirm these findings and a possible benefit on patients’ outcomes
Spring Meeting of the Young Researchers of SID, SIIA, SIMI, SIPREC, SISA
No full textThe VIII Spring Meeting of Young Researchers of the Italian Society of Diabetology (SID), the Italian Society of Arterial Hypertension (SIIA), the Italian Society of Internal Medicine (SIMI), the Italian Society of Cardiovascular Prevention (SIPREC) and the Italian Society for the Study of Atherosclerosis (SISA) “Basic and clinical research: Until grant let us apart” was held in Rimini on April 16-18, 2023. As is customary, the Congress was organized by the young members of the aforementioned scientific societies operating in the cardiometabolic field. The Congress featured five sessions dedicated to the discussion of the recent evidence from both basic and clinical researchers in cardiometabolic treatment and prevention. Many young researchers had the opportunity to present their scientific works in dedicated oral and poster sessions. In this report, we provided a summary of the main issues discussed during the Meeting lectures
A note on algebras of languages
No full textWe study the Boolean algebras R, CS, D of regular languages, context-sensitive languages and decidable languages, respectively, over any alphabet. It is well known that R ⊂ CS ⊂ D,
with proper inclusions. After observing that these Boolean algebras are all isomorphic, we study some immunity properties: for instance we prove that for every coinfinite decidable
language L there exists a decidable language L′ such that L ⊆ L′ , L′ −L is infinite, and there is no context-sensitive language L′′ , with L′′ ⊆ L′ unless L′′ − L is finite; similarly, for every
coinfinite regular language L there exists a context-sensitive language L′ such that L ⊆ L′ , L′−L is infinite, and there is no regular language L′′ such that L′′ ⊆ L′ , unless L′′−L is finite
Underdiagnosis and undertreatment of osteoporotic patients admitted in internal medicine wards in Italy (the REPOSI registry)
No full textNovel treatment options in IBS: butyric acid supplementation in predominant constipation (IBS-CP) versus predominant diarrhea (IBS-DP) IBS patients
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