1,721,028 research outputs found

    Fundraising strategies for early internationalizing startups. The dual model approach

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    Employing qualitative case study methods, this chapter investigates the influence of financing strategies on the international approach of a specific subset of early internationalizing European new ventures. Results show how the limited access to financial resources in the home country could be a triggering factor for startups to adopt an early internationalization approach. Investigated startups typically move their headquarters to countries that have a more developed financial market with the goal of having access to capital, while maintaining a strong operational presence in the country of origin (dual model approach). Despite some limitations, the study sheds new light on the issues that European startups, aiming at internationalizing their business since inception, confront regarding scaling-up in their home countries due to the lack of adequate domestic funding. It also identifies a novel international development path that European startups follow to address the obstacles preventing them from growing rapidly in their home country

    Startups and the hurdles of scaling-up

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    The start-up world is obsessed by the concept of scalability and exponential growth. That’s why scholars and practitioners started making a distinction between early-stage initiatives (start-ups) and real companies able to produce revenue and employment (the so-called scale-ups). A recently published article by Shepherd et al. (2021) points out how “too often the start-up and the scaling stages are merged (and the difference ignored), [this] has obstructed knowledge creation”. Moreover, in this field of research “wisdom of practice” is often more advanced than theory. Therefore, in an attempt of providing a clear-cut picture of the topic under investigation, we adopt the double-side perspective of practitioners and academics, who have been focusing their research efforts on this field for decades. In the end, the chapter also provides an overview of the main hurdles characterizing the scale-up proces

    Acute cholestatic hepatitis induced by bupropion prescribed as pharmacological support to stop smoking. A case report

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    We report the first case of acute cholestatic hepatitis induced by bupropion. This antidepressant was taken by a 49-year-old female as adjuvant treatment to stop smoking. After 20 days of bupropion, the patient presented a symptomatology characterized by asthenia, nausea and scleral icterus and biochemical analyses showed a dramatic increase in direct bilirubin [up to 28 mg/dl] and transaminases [up to 68-fold normal limits]. Antinuclear antibodies were positive [title = 1:80,- speckled pattern]. Biochemical analyses and antinuclear antibodies were normal two years earlier. The histology showed a pattern of acute hepatitis with involvement of bile ducts and with features of centrolobular cholestasis, Treatment with methylprednisolone was commenced and continued for 20 days. Liver enzymes and bilirubin returned to normal within two months of withdrawal of bupropion and remained normal during the 4-month follow-up, Antinuclear antibodies also became negative. Other causes of liver damage were excluded. Considering the clinical diagnostic scale for hepatotoxic adverse drug reaction, our patient showed a score compatible with the final diagnosis of bupropion-related cholestatic hepatitis

    Onetti fuera de sí. «Jamás leí a Onetti»

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    This collection published by Editorial Katatay, «Onetti out of his mind», carried out by the researchers Teresa Basile and Enrique Foffani, gathers a group of essays that aims to represent the work of the Uruguayan writer taking into account its relationship with other artistic expressions: music, painting, cinema, similarities with other poetic works from Rio de la Plata or unaddressed issues such as old age or gender paradigms. An unlikely Onetti that exceeds the sphere of previous studies and delivers unexpected new readings. This article about Onetti out of his mind deals with all the aspects taking as a thread the different traditions that use of the expression ‘out of his mind’ throughout time

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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