1,720,984 research outputs found

    Synchrotron radiation microtomography for the ex-vivo and in-vivo evaluation of nanoparticle-labeled stem cell homing in muscular tissue

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    In the perspective of clinical translation of stem cell research, the possibility to detect donor cells after transplantation and to track their fate is fundamental for a better understanding of their role in the regeneration of damaged tissues. In this article we summarize the results of ex-vivo and in-vivo X-ray computed microtomography experiments for 3D visualization of stem cells labeled with iron oxide nanoparticles and transplanted via intra-arterial infusion. We show that X-ray computed microtomography offers the possibility to detect with high definition and resolution human cells after transplantation, and opens new possibilities for experimental stem cell research

    Analysis of neutron diffraction profiles in bronze archaeological statuettes produced by solid lost wax casting.

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    In the framework of a research aiming to assess the suitability of neutron/x-ray non-destructive techniques for the characterization of archaeological objects, two bronze items were studied by neutron diffraction. The origins of two small statues are, respectively, Egyptian (XXI–XXX Dynasties, c1070–343 B.C.) and Etruscan (IV–III centuries B.C.), belonging to a private collection. By hard x-ray diffraction we previously verified that both statuettes have a coarse microstructure (big grains). From historical considerations we believe that both items were produced by solid lost wax processes of casting. This processing technique does not completely justify the presence of microstrains; as a consequence, due to unexpected neutron diffraction peak broadening, a non-uniform Sn wt% is suspected. In the present work we discuss this deduction by means of Rietveld analysis of the neutron diffraction profiles

    Relaxation of residual stress in MMC after combined plastic deformation and heat treatment

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    Neutron Diffraction shows that plastic pre-deformation and heat treatments have opposite effects on the residual stress in Al– SiCp composites. The thermal micro residual stress is relaxed or even reversed by pre-strains above 0.2%, but restored by heat treatments. The sense of relaxation changes above 400 C (the mixing temperature)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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