946 research outputs found
Thomas Percival. Etica medica, ovvero un Codice di istituzioni e precetti adattati alla condotta professionale dei medici e dei chirurghi
No full textA cura di Sara Patuzzo. Traduzione italiana di Giada Goracci. Con il contributo scientifico di Sebastiano Castellan
Castel di Pietra (Gavorrano – GR): relazione preliminare della campagna 2001 e revisione dei dati delle precedenti
No full textcura dell'articolo con testi di M. Belli, C. Cicali, C. Citter, M. Goracci, A. Magazzini, M. Pistolesi, H. SAlvadori, A. Sebastiani, E. Vaccar
The effects of undertreated chronic medical illnesses in patients with severe mental disorders
No full textSevere mental disorders such as bipolar disorder and schizophrenia often co-occur with chronic medical illnesses, especially cardiovascular disease and diabetes. These comorbidities are associated with a more severe course of mental illness, reduced quality of life, and premature mortality. Although the association between mental disorders and physical health complications has long been recognized, medical conditions remain undertreated in clinical psychiatric practice, and the life expectancy for individuals with serious psychiatric disorders is approximately 30% shorter than that of the general US population. Factors that are related to the mental illness (eg, cognitive impairment, reduced ability to function, and a lack of communication skills) as well as factors such as the high cost of medical care may make accessing general health care a difficult task for patients. Even when medical care is received by patients, the quality is often poor, and dangerous illnesses may be undiagnosed and untreated. In addition, harmful side effects of medications used to treat psychiatric disorders, unhealthy habits and lifestyles, and a possible genetic susceptibility to medical conditions increase the likelihood of comorbid physical conditions in patients with severe mental illness. Implementing behavioral interventions into clinical practice may help patients improve their overall health and prevent chronic medical conditions
Aripiprazole use during pregnancy, peripartum and lactation. A systematic literature search and review to inform clinical practice
No full textBackground Aripiprazole is used relatively frequently in women with bipolar disorder or schizophrenia in childbearing years, owing to its efficacy and relatively favorable side effect profile. As is the case for other psychotropic medications, for ethical reasons, no prospective randomized placebo controlled trial to assess aripiprazole safety during pregnancy has ever been conducted. However, animal data are available and the amount of exposure and outcome data for human fetuses and infants has recently increased, providing published prospective safety data in relatively large numbers of pregnant women treated with aripiprazole. The aim of this study was to perform a systematic literature search and review to critically evaluate the available data on the use of aripiprazole during pregnancy, peripartum and lactation. Methods PubMed, PsychInfo, and Cochrane Library were searched using the following search builder: (pregnancy OR pregnant OR gestation OR malformations OR perinatal OR reproduction OR organogenesis OR delivery OR breast-feeding OR lactation or peripartum or obstetric) AND aripiprazole. Reports that met the following pre-defined criteria were included in the present review: (1) published in English language in a peer-reviewed journal; (2) clearly defined use of aripiprazole during pregnancy and/or lactation and/or postpartum; (3) case report, case series, prospective, retrospective or cross-sectional studies. United States and European Medicine Agency prescribing information for aripiprazole were consulted as well and all the references of selected papers were cross checked for information pertaining to the use of aripiprazole during pregnancy, peripartum and lactation. Results A total of 549 items published in a period ranging from 1995 to 2017, were retrieved from the search databases and reference cross check. One-hundred-fifty-three duplicate items were removed, 176 titles were deemed as not pertinent, 220 abstracts and 122 full-text articles were assessed for eligibility and 93 titles were included for qualitative synthesis. United States and European Medicine Agency prescribing information for aripiprazole were consulted and the selected manuscript references were cross checked. No randomized placebo controlled trial was found but relatively large prospective studies, large database studies, and several case reports and case studies were identified and summarized. Conclusions As is the case for other antipsychotics, definitive evidence on aripiprazole reproductive safety is lacking, but newer safety data are relatively reassuring. In many cases, the potential benefits of aripiprazole for patients with bipolar disorder or schizophrenia outweigh the potential risks. © 2017 Elsevier B.V
Playing it fashionably queer: Mae West's performing sexuality
No full text“Marriage is a fine institution, but I’m not ready for an institution”. With this challenging innuendo, the American actress and author Mae West offers an insight into gender performativity and heteronormativity through marriage in a period, the “Roaring Twenties”, in which sexual and gender politics could not be put into scrutiny. Her vamp persona and the elaborated iconography that she crafted on her character gave birth to a meticulous semiotics of the body that eventually undermined the American social context of the time fostering on the one hand, an image of heterosexual desire, and on the other hand an appealing icon to a gay market. This article ventures a queer-oriented perspective on West’s charismatic character and on the intertwined effects that tie semiotics to body language, especially focussing on the plays Sex (1926) and The Drag (1927)
Revisiting the Canadian Lynx Time Series Analysis Through TARMA Models
No full textThe class of threshold autoregressive models has been proven to be a powerful and appropriate tool to describe many dynamical phenomena in different fields. In this work, we deploy the threshold autoregressive moving-average framework to revisit the analysis of the benchmark Canadian lynx time series. This data set has attracted great attention among non-linear time series analysts due to its asymmetric cycle that makes the investigation very challenging. We compare some of the best threshold autoregressive models (TAR) proposed in literature with a selection of thresholdautoregressive moving-average models (TARMA). The models are compared under different prospectives: (i) goodness-of-fit through information criteria, (ii) their ability to reproduce characteristic cycles, (iv) their capability to capture multimodality and (iii) forecasting performance. We found TARMAmodels that perform better than TAR models with respect to all these aspects
Mood stabilisers and pregnancy outcomes - a review
No full textThe purpose of this review is to give useful information to guide clinicians when treating pregnant women affected by bipolar disorder. This review focuses on mood stabilizers including lithium, sodium valproate, carbamazepine, oxcarbazepine, gabapentin, lamotrigine and topiramate. Data have been extracted from a MEDLINE search. Data from prospective, retrospective and case-control studies as well as systematic reviews, meta-analysis and data from Pregnancy Registry were included. Major congenital malformations as well as specific malformations were reported for each drug. Preliminary findings seem to identify lamotrigine as one ofthe safest antiepileptic drugs to be used in pregnancy. Teratogenity risk oftopiramate is still largely unknown and there are not enough studies to draw even preliminary conclusions. Preliminary studies failed to report an increased risk for major congenital malformations among gabapentin or.oxcarbazepine exposed pregnancies. Even if raising less concern when compared to valproate, carbamazepine should be avoided for its documented teratogenity risk. Valproate seems to be the worst considering major congenital malformations, specific malformations as,well as its detrimental effects on neurodevelopment. On the other hand, lithium might be considered a good option when treating pregnant women affected by bipolar disorder. Given the limited research on mood stabilizers in pregnancy, clinicians need to be very careful when treating child bearing age women. Clinicians have to balance the potential teratogenityrisk against that of untreated mental illness considering individual circumstances such as severity of illness and risk of relapse
Le diverse espressioni dell'ansia e della paura: per iniziare a comprendere il mondo di coloro che soffrono di disturbi d'ansia
No full textRecensione a Allyna E. Ward, Women and Tudor Tragedy, Feminizing Counsel and Representing Gender (Madison, Fairleigh Dickinson, 2013)
No full textDurante il periodo Tudor lo sviluppo delle idee riguardanti il genere ed il ruolo della donna all’interno della società, nello specifico la donna come scrittrice o personaggio letterario e politico, rappresenta il punto centrale della revisione sul gender che caratterizzò la nascente Europa moderna. L’opera di Ward descrive il processo attraverso il quale, durante il regno dei Tudor, l’attenzione verso la cultura e la politica passa da una male-oriented structure tanto agognata da Enrico VIII a una che, paradossalmente, viene governata da donne: prima da Maria Tudor e poi da Elisabetta Tudor
- …
