1,721,041 research outputs found
Towards an observer-oriented theory of shape comparison
Full text linkIn this position paper we suggest a possible metric approach to shape comparison that is based on a mathematical formalization of the concept of observer, seen as a collection of suitable operators acting on a metric space of functions. These functions represent the set of data that are accessible to the observer, while the operators describe the way the observer elaborates the data and enclose the invariance that he/she associates with them. We expose this model and illustrate some theoretical reasons that justify its possible use for shape comparison
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Angiosuppressive and angiostimulatory effects exerted by synthetic partial sequences of endostatin
No full textPurpose: Endostatin, a peptide derived from proteolysis
of collagen XVIII, is an endogenous inhibitor of angiogenesis
and tumor growth. We have synthesized five peptide fragments
designed to cover the whole length of the endostatin
molecule (containing 40–50 amino acids each) with the aim
of exploring the possibility that a specific sequence within
the molecule might be responsible for its antiangiogenic
effects.
Experimental Design: The five peptide sequences,
termed fragments I, II, III, IV, and IVox, the latter bearing
the original disulfide bond Cys135-Cys165, were investigated
for their effects on cultured endothelial cells, on enzyme
activities related to angiogenesis, on tube formation in threedimensional
gel matrices, in vivo in the avascular rabbit
cornea assay, and in an experimental tumor burden paradigm.
Results: Both the fragment covering the COOH-terminal
endostatin region, fragment IV, and particularly fragment
IVox, retained the angioinhibitory effects of endostatin.
Fragment IVox strongly inhibited endothelial cell
migration and proliferation, in vitro tube formation, and in
vivo angiogenesis, displaying a potency comparable with
that of endostatin. When tested in vivo on tumor growth,
fragment IVox demonstrated to be more effective than fulllength
endostatin. Unexpectedly, fragment III exhibited
proangiogenic activity, increasing endothelial cell migration,
producing neovascularization to an extent similar to that of
vascular endothelial growth factor, and enhancing the angiogenic
response to vascular endothelial growth factor in
the cornea assay. Peptides encompassing the NH2-terminal
region of endostatin (fragments I and II) had negligible
effects on angiogenesis.
Conclusions: In view of these results, which show strikingly
distinct profiles of endostatin fragments, we propose
that the amino acid sequence of endostatin contains both
angiosuppressive and angiostimulatory domains
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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