1,721,009 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Polynucleotide Analysis of Human Globin Variants

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    In a search for open reading frames in several known polynucleotide sequences of structural genes, we found that the anti-sense strand of the β and ε human, α and β rabbit globin DNA fragments contain translatable sequences even longer than the coding sequences of the globin strand. A more detailed analysis of the human β and ε sequences reveals that (a) Translatable sequences use the same frame as the globin coding strand, with the opposite polarity (b) None of the many β globin variants either introduces a termination codon or removes the putative AUG initiation codon in the anti-sense strand (c) Leader sequences identical to those found in the 5’ non-coding region of globin mRNA, are found upstream the AUG codon (d) Sequences complementary to both introns, present on both β and ε globin genes, contain termination codons in all reading frames, as in the case of the intron sequences themselves, and splicing rules are respected. We postulate the existence of protein(s) coded by the complementary strand of β and ε human globin translated strand and that these two hypothetical genes also contain untranslated intron sequences

    "Può l’elica non-senso di un gene codificare per una proteina ?"

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    Durante lo sviluppo del T4 e di altri batteriofagi, come pure in molti altri sistemi biologici, varie porzioni del genoma sono trascritte simmetricamente. La funzione biologica di questi RNA, complementari a RNA messaggero, è ancora sconosciuta : è possibile ad esempio che siano realmente tradotti in proteine. Per verificare questa ipotesi abbiamo analizzato con il calcolatore l’elica complementare all’elica senso dei molti geni strutturali di cui è conosciuta la sequenza dell’RNA messaggero, per vedere se fossero presenti sequenze di codoni di lunghezza compatibile con la presenza di eventuali geni. Abbiamo così analizzato tra le altre le sequenze...(continua

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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