16 research outputs found
Prevalence of skin tears in the extremities among elderly residents at a nursing home in Denmark
Objective: The aim of the study was to determine the prevalence of skin tears in the extremities and explore factors in relation to skin tears in elderly residents at a Danish nursing home. Method: The study was designed as a point prevalence survey and conducted at a nursing home with 140 residents >65 years of age. The residents were assessed for presence, number and location of skin tears. Data were collected using a data collection sheet developed for this study. The survey team consisted of four expert nurses from a university hospital (two dermatology and two wound care nurses). Data were collected over a period of 10 hours spread over two days. Results: Of the 128 participating residents six had skin tears, yielding a prevalence of 4.6 %. In total, 10 skin tears were observed in the 6 residents. The frequency of previous skin tears was 19.5 %. This frequency was significantly higher in residents with skin tears than in those without skin tears (83.3 % versus 16.4 %, p<0.001). Analysis of the relation between skin tears or previous skin tears versus without skin tears or previous skin tears showed significant differences related to the presence of ecchymosis (76.9 %versus 14.7 %, p<0.0001). There were no other significant factors observed. Conclusion: The low prevalence found in this study may reflect the focus on prevention of skin tears that the nursing home has maintained over the past year. Nevertheless, the appropriate prevention and management of residents with skin tears is an ongoing challenge for health professionals. </jats:sec
Combined external and intracavitary irradiation in treatment of advanced cervical carcinomas : predictive factors for local tumor control and early recurrences
In a series of 131 primary cervical carcinomas in FIGO stages I-IV suitable for combined external pelvic and intraluminal cervical-vaginal brachytherapy predictive and prognostic factors were analyzed with regard to locoregional tumor control, recurrences and survival data. Patients with prior surgery or patients treated with external beam therapy alone were excluded from this series. Concomitant chemotherapy was given to 47 patients (36%). The external beam therapy was given with a four-field technique (50-60 Gy) and brachytherapy with high dose-rate (Ir-192) using a ring applicator set. The dose (18-30 Gy) was specified according to the rules in ICRU 38 (a minimum dose to the surface of the target volume). Three or five fractions were given once a week in parallel with external beam irradiation. A CT-based 3-D dose-planning system (TMS) was used for the external beam therapy and for the brachytherapy planning (PLATO). The mean age of the patients was 65 years. One hundred and seven tumors were squamous cell carcinomas (82%) and 24 adenocarcinomas or adenosquamous carcinomas. One hundred and eight tumors were in FIGO stages I-II and 23 tumors in stages III-IV. The mean tumor diameter was 44 mm. Most tumors (92%) were moderately well or poorly differentiated. The primary cure rate of the complete series was 92% and 98% after chemoradiotherapy. Squamous cell carcinomas had complete remission in 96% and adenocarcinomas in 81% (Pearson Chi-square; P=0.00002). Tumor size was also highly significantly associated with local tumor control. The brachytherapy dose, the combined external and brachytherapy dose and the number of days of interruption (delay) of external irradiation were all significant predictive factors of local tumor control. In the complete series 39 recurrences (30%) were recorded. A lower FIGO stage, chemoradiotherapy, squamous cell histology, diploid DNA-profile, a higher brachytherapy dose, more brachytherapy fractions and a higher total combined irradiation dose were favorable factors with regard to the risk of tumor recurrences. The overall survival rate was 50% and the cancer-specific survival rate 65%. Tumor size was the strongest individual prognostic factor in multivariate analysis. Chemoradiotherapy therapy versus radiotherapy alone and squamous cell carcinomas versus adenocarcinomas were associated with improved survival rates. Early radiation reactions were recorded in 58% (mostly grade 1) and serious late radiation reactions (grade 3-4) in 11%.</p
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LIMPRINT: prevalence of chronic edema in health services in Copenhagen, Denmark
Background: The International Lymphedema Framework developed an international study, Lymphedema Impact and Prevalence International (LIMPRINT) to estimate the prevalence and impact of chronic edema in heterogeneous populations.
Methods and results: A validation study using the LIMPRINT methodology was undertaken in Denmark. Participants with CO were identified from in-patient services and compared to those identified within a specialist lymphoedema service and 3 primary care settings. Of 452 inpatients available for screening CO was present in 177(39%) and absent in 275(61%). In addition, 723 participants were found from specialist and primary care services (LPCS). In-patients were significantly older and more likely to be underweight or normal weight. They were more likely to suffer from heart failure/IHD (44.6% vs 23.4%, p<0.001) and have neurological problems (18.1% vs 10.9% p=0.009). The inpatient group were nearly all suffering from secondary Lymphoedema and were less likely to have a cancer or venous diagnosis, but more likely to have immobility as the cause of CO (44.0% vs 17.7%, p<0.001). No in-patients had midline CO compared to 30 within LPCS. Fewer in the in-patient group had standard CO treatment (17.1% vs 73.5%, p<0.001) and subjective control of swelling was worse (19.9% vs 66.7%, p<0.001). Whilst the in-patient group experienced fewer acute infections, when they did so, they were more likely to be admitted to hospital for this (78.6% vs 51.0%, p=0.049).
Conclusion: The prevalence of CO in inpatient facilities is high and those with CO have multiple comorbidities that vary according to setting. The feasibility study showed the methodology could be adapted for use in different health systems
Human peripheral B cell development
Since the middle of the nineties, our understanding of human peripheral B cell development has gradually increased. Today, the B cell compartment has been divided into three main populations; transitional, naive and memory B cells. In Mats Bermark's laboratorium, a cell surface marker identifying a novel peripheral B cell population has been found. The work performed during this thesis aimed to characterize the novel B cell population by comparing it with the major already described peripheral B cell populations. Novel B cells were found to be smaller than memory B cells. The antibody genes were found to contain less mutations than those of memory B cells. Furthermore, novel B cells were found to be less prone to enter apoptosis than transitional B cells. A screening experiment using flow cytometry added support to the hypothesis that the novel B cells are different from the already described populations. The results suggests that the novel B cell population is a distinct subpopulation post- or parallel to the naive population. Novel B cells might be able to differentiate into IgM+ memory B cells. In order to verify this, new experiments are neede
JAWABAN SOAL UTS HAKI
A. STUDI KASUS ( SK )
Pertanyaan Type C :
paparkan dan jelaskan product knowledge (KS)/ produk tim anda (KP)
Jawaban :
Produk yang akan saya jelaskan produk prangkat komputer yang bermark AMBATIK”
Yang terdiri dari dua kata “amba” dan “tik”, amba (luas), tik (titik), jadi Ambatik berarti titik luas dan dipatenkan oleh Penemuan AMBATIK ini dibuat oleh 5 pemuda pemudi Defsy. Dibuat dinegara indonesia pada provinsi Lampung tahun 2018.
Produk ini memiliki rahasia dagang Memiliki sistem operasi yang berbeda dengan komputer lainnya namanya adalah Max OS atau yang bisa disebut Maksimal Operating System.
Selain itu memiliki desain industri Komputer ini memiliki warna casing hitam yang dilapisi list warna biru, dibalut dengan desain batik batik dibagian atas dan samping CPU, dan memiliki khas tersendiri. Komputer ini berbentuk kotak memanjang, monitor serta CPU menyatu dengan PC. Monitor bisa dipisahkan dengan CPU. Jika dipisahkan bisa berfungsi sebagai tablet. Selain itu memiliki Spesifikasi komputerPC Processor : Intel Core i7 3770 K
Motherbord : AMBATIK Sabertooth Defsy 887
VGA : Gigabyte BTX690
Ram : 32 Gb
Hardisk : Western digital 1 Tb Caviar
SSD : OCZ Vector 256 Gb
DVD Room : Bluray Combo SE-406 B
Cooler/kipas : Corsair H100i
PSU : SeaSonic P860
. Spesifikasi Monitor
Size : 30’ TN Panel
Resolution : 1920x1080/Full HD
Connectivity : D-Sub/Dvi/HDMI/Headphone Jack
Cable Included : HDMI
Response Time : 1 Ms
Dan memiliki tata letak sircuitly Monitor didesain menempel dengan CPU.
OS (Operating System) Defsy yang bawaan dari PC AMBATIK
JAWABAN SOAL UTS HAKI
A. STUDI KASUS ( SK )
Pertanyaan Type C :
paparkan dan jelaskan product knowledge (KS)/ produk tim anda (KP)
Jawaban :
Produk yang akan saya jelaskan produk prangkat komputer yang bermark AMBATIK”
Yang terdiri dari dua kata “amba” dan “tik”, amba (luas), tik (titik), jadi Ambatik berarti titik luas dan dipatenkan oleh Penemuan AMBATIK ini dibuat oleh 5 pemuda pemudi Defsy. Dibuat dinegara indonesia pada provinsi Lampung tahun 2018.
Produk ini memiliki rahasia dagang Memiliki sistem operasi yang berbeda dengan komputer lainnya namanya adalah Max OS atau yang bisa disebut Maksimal Operating System.
Selain itu memiliki desain industri Komputer ini memiliki warna casing hitam yang dilapisi list warna biru, dibalut dengan desain batik batik dibagian atas dan samping CPU, dan memiliki khas tersendiri. Komputer ini berbentuk kotak memanjang, monitor serta CPU menyatu dengan PC. Monitor bisa dipisahkan dengan CPU. Jika dipisahkan bisa berfungsi sebagai tablet. Selain itu memiliki Spesifikasi komputerPC Processor : Intel Core i7 3770 K
Motherbord : AMBATIK Sabertooth Defsy 887
VGA : Gigabyte BTX690
Ram : 32 Gb
Hardisk : Western digital 1 Tb Caviar
SSD : OCZ Vector 256 Gb
DVD Room : Bluray Combo SE-406 B
Cooler/kipas : Corsair H100i
PSU : SeaSonic P860
. Spesifikasi Monitor
Size : 30’ TN Panel
Resolution : 1920x1080/Full HD
Connectivity : D-Sub/Dvi/HDMI/Headphone Jack
Cable Included : HDMI
Response Time : 1 Ms
Dan memiliki tata letak sircuitly Monitor didesain menempel dengan CPU.
OS (Operating System) Defsy yang bawaan dari PC AMBATIK
