1,722,746 research outputs found
Registration of ILC 8262, a Cold-Tolerant Germplasm Line of Chickpea
No full textRegistration of ILC 8262, a Cold-Tolerant Germplasm Line of Chickpe
Plan of Lots 8697, 8696, 8262 & 8263 G.1
No full textPlan of lots 8697, 8696, 8262 & 8263 G.I. of Bonanza City. Includes Bonanza Creek and the Nakusp and Sandon Railway. Accession no: 2019.2.090Title note: An expressive alternative title was developed by SSHS, which has been retained as the primary label for this map. Title proper has been recorded as an alternative title within the context of BCRDH
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
RRS James Clark Ross Cruise 194, 12-23 Dec 2008. Drake Passage repeat hydrography: WOCE Southern Repeat Section 1b – Burdwood Bank to Elephant Island.
Get PDFA repeat hydrographic section (WOCE section SR1b) across Drake Passage was occupiedduring December 2008 aboard the RRS James Clark Ross (JR194). This is a section across theAntarctic Circumpolar Current at its narrowest point, with the primary objective of this cruisebeing to determine the currents, characteristics and transports of the various water masses.A total of 32 CTD/LADCP stations were sampled across Drake Passage and down to Rothera,of which 30 comprised the SR1b repeat hydrographic section between Burdwood Bank andElephant Island, and the first two were test stations. In addition to temperature, salinity andoxygen profiles from the sensors on the CTD package, water samples from the 24-bottle rosettewere analysed for salinity at each station, in order to calibrate the CTD salinity profiles. Also,samples were collected from the shipís underway system to calibrate and complement the datacontinually collected by the OceanLogger. Full depth velocity measurements were made atevery station by an LADCP (lowered acoustic Doppler current profiler) mounted on the frameof the rosette. Throughout the cruise, velocity data in the upper few hundred metres of thewater column were collected by the shipsí VMADCP (vessel mounted acoustic Doppler currentprofiler) mounted on the hull. Meteorological variables were monitored using the onboardsurface water and meteorological sampling system. Bathymetry data were also collected usinga Simrad EA600 echo-sounder, and 7 Argo floats were deployed. A new addition to thescientific complement was the study of microbial abundance and dynamics within the DrakePassage section. Flow cytometry was used to compare the abundance of dominant microbialplankton groups, and a scintillation counter to assess the productivity rates of thebacterioplankton.The work is a component of the "Sustained Observations" supported by NERC's Oceans 2025programme. This report describes the methods used to acquire and process the data on boardthe ship during cruise JR194
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties
No full textCholesteryl
ester transfer protein (CETP) represents one of the
key regulators of the homeostasis of lipid particles, including high-density
lipoprotein (HDL) and low-density lipoprotein (LDL) particles. Epidemiological
evidence correlates increased HDL and decreased LDL to coronary heart
disease (CHD) risk reduction. This relationship is consistent with
a clinical outcomes trial of a CETP inhibitor (anacetrapib) combined
with standard of care (statin), which led to a 9% additional risk
reduction compared to standard of care alone. We discuss here the
discovery of MK-8262, a CETP inhibitor with the potential for being
the best-in-class molecule. Novel in vitro and in vivo paradigms were
integrated to drug discovery to guide optimization informed by a critical
understanding of key clinical adverse effect profiles. We present
preclinical and clinical evidence of MK-8262 safety and efficacy by
means of HDL increase and LDL reduction as biomarkers for reduced
CHD risk
- …
